Stopping Aspirin Intake Raises Risks of Heart Attack

Doctors commonly prescribe daily low-dose aspirin after a heart attack to reduce the risk of having a second cardiovascular event. (Reuters)
Doctors commonly prescribe daily low-dose aspirin after a heart attack to reduce the risk of having a second cardiovascular event. (Reuters)
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Stopping Aspirin Intake Raises Risks of Heart Attack

Doctors commonly prescribe daily low-dose aspirin after a heart attack to reduce the risk of having a second cardiovascular event. (Reuters)
Doctors commonly prescribe daily low-dose aspirin after a heart attack to reduce the risk of having a second cardiovascular event. (Reuters)

Doctors commonly prescribe daily low-dose aspirin after a heart attack to reduce the risk of having a second cardiovascular event.

About one in six patients however stop taking their aspirin within three years, a Swedish study found. It warned against stopping the low dose of aspirin, because it raises the risk of heart attack or stroke by nearly 40 percent.

Lead author of the study Dr. Johan Sundstrom told Reuters Health that low-dose aspirin makes the platelets in the blood less likely to form clots. This is especially useful in the coronary or carotid arteries, where blood clots may lead to myocardial infarctions and strokes.

Sundstrom, an epidemiologist at Uppsala University added that millions of patients worldwide take aspirin on a daily basis and might consider stopping at some time during their life.

“We performed this study to help physicians and patients to make an informed decision whether or not to stop aspirin use,” he explained.

To see if risk rises after a patient stops aspirin therapy, Sundstrom’s team used nationwide medical and death registries to identify patients over age 40 taking low-dose aspirin. In Sweden, low-dose aspirin is available only by prescription, so the researchers were also able to see who continued filling their prescriptions between 2005 and 2009.

The researchers analyzed records for 601,527 patients, who were cancer-free and had taken at least 80 percent of their prescribed aspirin doses during the first year of treatment. After excluding a small proportion of patients whose medical records showed a reason for stopping aspirin, such as surgery or a case of severe bleeding, they found that about 15 percent of the full group had stopped taking their aspirin after about three years.

At the end of the study period, there were a total of 62,690 cardiovascular events, defined as hospitalization for a heart attack or stroke, or cardiovascular death.

The study lead author said patients who discontinued aspirin had a 37 percent higher rate of cardiovascular events than those who continued. That translates to one extra cardiovascular event each year among every 74 patients who stopped taking aspirin.

The risk increased shortly after discontinuation, and did not appear to diminish over time, he added.

“Adherence to low-dose aspirin treatment in the absence of major surgery or bleeding is likely an important treatment goal,” stressed Sundstrom.



Biggest Piece of Mars on Earth is Going Up for Auction in New York

A Martian meteorite, weighing 54.388 lbs. (24.67 kg), said to be the largest piece of Mars on Earth, estimated at $2 - 4 million, is displayed at Sotheby's, in New York, Wednesday, July 9, 2025, part of their Geek Week auction, July 16, 2025. (AP Photo/Richard Drew)
A Martian meteorite, weighing 54.388 lbs. (24.67 kg), said to be the largest piece of Mars on Earth, estimated at $2 - 4 million, is displayed at Sotheby's, in New York, Wednesday, July 9, 2025, part of their Geek Week auction, July 16, 2025. (AP Photo/Richard Drew)
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Biggest Piece of Mars on Earth is Going Up for Auction in New York

A Martian meteorite, weighing 54.388 lbs. (24.67 kg), said to be the largest piece of Mars on Earth, estimated at $2 - 4 million, is displayed at Sotheby's, in New York, Wednesday, July 9, 2025, part of their Geek Week auction, July 16, 2025. (AP Photo/Richard Drew)
A Martian meteorite, weighing 54.388 lbs. (24.67 kg), said to be the largest piece of Mars on Earth, estimated at $2 - 4 million, is displayed at Sotheby's, in New York, Wednesday, July 9, 2025, part of their Geek Week auction, July 16, 2025. (AP Photo/Richard Drew)

For sale: A 54-pound (25-kilogram) rock. Estimated auction price: $2 million to $4 million. Why so expensive? It's the largest piece of Mars ever found on Earth.

Sotheby's in New York will be auctioning what's known as NWA 16788 on Wednesday as part of a natural history-themed sale that also includes a juvenile Ceratosaurus dinosaur skeleton that's more than 6 feet (2 meters) tall and nearly 11 feet (3 meters) long, The Associated Press reported.

According to the auction house, the meteorite is believed to have been blown off the surface of Mars by a massive asteroid strike before traveling 140 million miles (225 million kilometers) to Earth, where it crashed into the Sahara. A meteorite hunter found it in Niger in November 2023, Sotheby's says.

The red, brown and gray hunk is about 70% larger than the next largest piece of Mars found on Earth and represents nearly 7% of all the Martian material currently on this planet, Sotheby's says. It measures nearly 15 inches by 11 inches by 6 inches (375 millimeters by 279 millimeters by 152 millimeters).

"This Martian meteorite is the largest piece of Mars we have ever found by a long shot," Cassandra Hatton, vice chairman for science and natural history at Sotheby's, said in an interview. "So it´s more than double the size of what we previously thought was the largest piece of Mars."

It is also a rare find. There are only 400 Martian meteorites out of the more than 77,000 officially recognized meteorites found on Earth, Sotheby's says.

Hatton said a small piece of the red planet remnant was removed and sent to a specialized lab that confirmed it is from Mars. It was compared with the distinct chemical composition of Martian meteorites discovered during the Viking space probe that landed on Mars in 1976, she said.

The examination found that it is an "olivine-microgabbroic shergottite," a type of Martian rock formed from the slow cooling of Martian magma. It has a course-grained texture and contains the minerals pyroxene and olivine, Sotheby's says.

It also has a glassy surface, likely due to the high heat that burned it when it fell through Earth's atmosphere, Hatton said. "So that was their first clue that this wasn't just some big rock on the ground," she said.

The meteorite previously was on exhibit at the Italian Space Agency in Rome. Sotheby's did not disclose the owner.

It's not clear exactly when the meteorite hit Earth, but testing shows it probably happened in recent years, Sotheby's said.

The juvenile Ceratosaurus nasicornis skeleton was found in 1996 near Laramie, Wyoming, at Bone Cabin Quarry, a gold mine for dinosaur bones. Specialists assembled nearly 140 fossil bones with some sculpted materials to recreate the skeleton and mounted it so it's ready to exhibit, Sotheby's says.

The skeleton is believed to be from the late Jurassic period, about 150 million years ago, Sotheby's says. It's auction estimate is $4 million to $6 million.

Ceratosaurus dinosaurs were bipeds with short arms that appear similar to the Tyrannosaurus rex, but smaller. Ceratosaurus dinosaurs could grow up to 25 feet (7.6 meters) long, while the Tyrannosaurs rex could be 40 feet (12 meters) long.

The skeleton was acquired last year by Fossilogic, a Utah-based fossil preparation and mounting company.

Wednesday's auction is part of Sotheby's Geek Week 2025 and features 122 items, including other meteorites, fossils and gem-quality minerals.