Researchers Produce Smallest Data Recorder Made of Microbes

A sample bottle containing Escherichia coli bacteria is seen at the Health Protection Agency in north London. (Reuters)
A sample bottle containing Escherichia coli bacteria is seen at the Health Protection Agency in north London. (Reuters)
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Researchers Produce Smallest Data Recorder Made of Microbes

A sample bottle containing Escherichia coli bacteria is seen at the Health Protection Agency in north London. (Reuters)
A sample bottle containing Escherichia coli bacteria is seen at the Health Protection Agency in north London. (Reuters)

Researchers at Columbia University Medical Center (CUMC) have converted a natural bacterial immune system into a microscopic data recorder, laying the groundwork for a new class of technologies that use bacterial cells for everything from disease diagnosis to environmental monitoring.

According to the German news agency (dpa), the researchers modified an ordinary laboratory strain of the ubiquitous human gut microbe Escherichia coli, enabling the bacteria to not only record their interactions with the environment, but also time-stamp the events.

Harris Wang, assistant professor in the Department of Pathology and Cell Biology and Systems Biology at CUMC said that such bacteria, swallowed by a patient, might be able to record the changes they experience through the whole digestive tract, yielding an unprecedented view of previously inaccessible phenomena.

Wang said this system is a natural biological memory device, reported phys.org website.

From an engineering perspective that is actually quite nice, because it is already a system that has been honed through evolution to be really great at storing information, he added.

To build their microscopic recorder, the research team modified a piece of DNA called a plasmid, giving it the ability to create more copies of itself in the bacterial cell in response to an external signal.



Cutting Off Rhinos' Horns is a Contentious Last Resort to Stop Poaching. New Study Found it Works

A de-horned rhino grazes in South Africa's Pilanesberg National Park, Feb. 25, 2025. (AP Photo/Jerome Delay)
A de-horned rhino grazes in South Africa's Pilanesberg National Park, Feb. 25, 2025. (AP Photo/Jerome Delay)
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Cutting Off Rhinos' Horns is a Contentious Last Resort to Stop Poaching. New Study Found it Works

A de-horned rhino grazes in South Africa's Pilanesberg National Park, Feb. 25, 2025. (AP Photo/Jerome Delay)
A de-horned rhino grazes in South Africa's Pilanesberg National Park, Feb. 25, 2025. (AP Photo/Jerome Delay)

Cutting off the horns of sedated rhinos with a chainsaw has been viewed by wildlife conservationists in Africa for more than 30 years as a necessary evil to save the iconic endangered species from poaching.

They hoped the drastic action was working, but evidence was scarce.

Now, a study published Thursday in the academic journal Science has found that dehorning rhinos has led to a large reduction in poaching in game reserves in and around the Kruger National Park in northern South Africa — an area that's home to 25% of the world's rhinos and is especially vulnerable to poaching.

The results of the seven-year study that ended in 2023 are seen as long-awaited evidence that removing rhinos' horns — which needs to be done every one to two years because they grow back — helps them survive, even if the animals lose part of their makeup.

Consistently reduced poaching The conclusions seem obvious. Lucrative illegal markets in parts of southeast Asia and China crave rhino horns for use in traditional medicines, and removing the rhinos' horns take away what poachers are after.

But Tim Kuiper, a biodiversity scientist at South Africa's Nelson Mandela University and the lead author of the study, said it was new to have long-term data from multiple sites on dehorning rhinos. He said the study, conducted between January 2017 and December 2023, focused on 11 reserves in the Kruger area and compared data from eight that dehorned their rhinos against the three that didn't.

It also analyzed data from the reserves before and after they dehorned their rhinos.

The study showed that dehorning consistently reduced poaching, Kuiper said. It found that the dehorning of more than 2,000 rhinos resulted in a 78% reduction in poaching in those eight reserves, providing some confirmation that such an invasive intervention was worth it.

“It is a big part of what a rhino is, having a horn,” The Associated Press quoted Kuiper as saying. “So having to remove it is kind of a necessary evil, if I can put it that way. But it’s very effective. There’s no doubt it saved hundreds of rhinos' lives.”

South Africa has the largest numbers of black and white rhinos. Namibia, Zimbabwe and Kenya also have significant populations. There are around 17,500 white rhinos and 6,500 black rhinos left in the world, with black rhino numbers reduced from 70,000 in 1970 to less than 2,500 by the time poaching reached a crisis point in the mid-1990s, according to the Save the Rhino organization.

Dehorning was not always accepted Dehorning rhinos started in southern Africa as early as 1989. It has not been accepted without question.

There has been opposition from animal rights activists but also questions from conservationists over what impact it has on a rhino's wellbeing, and what a future might look like with more hornless rhinos.

Vanessa Duthe, a rhino researcher in South Africa not involved in the study, said rhinos use their horns to defend themselves against predators, to compete for territory and, in the case of black rhinos, to look for food. There is also evidence that dehorned rhinos adjust their movements to live in smaller ranges, she said.

She said conservationists don't know the full impacts of dehorning, but research had found it had no adverse effect on rhinos' breeding rates or mortality rates.

“What we do know is that the benefits of dehorning by far outweigh any ecological cost that we’re aware of today,” Duthe said. She said dehorning a rhino now takes around 10 minutes and the process causes minimum distress.

Blindfolds and earmuffs are put on sedated rhinos during dehorning, which also provides an opportunity to microchip rhinos and collect samples that aid research.

Only one part of the battle Conservationists agree that dehorning alone will not end rhino poaching and Kuiper said he saw it as a short-to-mid-term solution.

Other efforts like more effective law enforcement and better support for game rangers on the frontline are key.

While South Africa has helped pull rhinos back from the threat of extinction, more than 400 rhinos a year are still killed by poachers in the country.

The dehorning study was a collaboration between scientists from three South African universities, Oxford University in England and game reserve managers and rangers. It also involved the South African National Parks department, the World Wildlife Fund and the Rhino Recovery Fund.