Nine people were killed, including six protesters and a member of the Iranian Revolutionary Guards, during demonstrations took place in the Isfahan region on Monday, said official state television.
A pedestrian and a member of the police were among the victims of the fifth day of protests that have been raging in Iran since Thursday.
State TV reported that six people were killed during an attack on a police station in the town of Qahdarijan.
It also added an 11-year-old boy and a 20-year-old man were killed in the town of Khomeinishahr, while a member of the Revolutionary Guards was killed in the town of Najafabad.
It said all three were shot by hunting rifles, which are common in the Iranian countryside.
Meanwhile, in Tehran alone, 450 protesters have been arrested in the last three days, the semi-official ILNA news agency reported Tuesday.
ILNA quoted Ali Asghar Nasserbakht, a security deputy governor of Tehran, as saying security forces arrested 200 protesters Saturday, 150 Sunday and 100 Monday.
The government said it was temporarily restricting access to the Telegram messaging app and Instagram. There were reports that internet mobile access was blocked in some areas.