Russian Scientists Revive Frog’s Heart after 45 Days of Freezing

A research scientist for the Washington Department of Fish and Wildlife pushes a Passive Integrated Transponder (PIT) tag under the skin of an Oregon spotted frog that will help in tracking the juvenile frog raised at the Woodland Park Zoo. AP file photo
A research scientist for the Washington Department of Fish and Wildlife pushes a Passive Integrated Transponder (PIT) tag under the skin of an Oregon spotted frog that will help in tracking the juvenile frog raised at the Woodland Park Zoo. AP file photo
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Russian Scientists Revive Frog’s Heart after 45 Days of Freezing

A research scientist for the Washington Department of Fish and Wildlife pushes a Passive Integrated Transponder (PIT) tag under the skin of an Oregon spotted frog that will help in tracking the juvenile frog raised at the Woodland Park Zoo. AP file photo
A research scientist for the Washington Department of Fish and Wildlife pushes a Passive Integrated Transponder (PIT) tag under the skin of an Oregon spotted frog that will help in tracking the juvenile frog raised at the Woodland Park Zoo. AP file photo

Russian scientists have managed to revive the heart of a frog after freezing it for 45 days as part of experiments aiming to prolong the period during which an organ is able to function normally and vitally.

This achievement is a significant development in the organ transplant field that would contribute in saving people’s lives.

Organ transplants such as kidneys and heart had long been a fictional idea. However, such transplants are currently practiced in hospitals in many countries.

But transplant scientists and surgeons now face a challenge in the ability of maintaining a specific organ functional after removing it from the donor. For instance, the period during which the heart muscle can be preserved before transferring it to the patient is not more than 6 hours, and this timeframe may not be sufficient for the transfer.

Studies indicate that doctors spoil about 60 percent of the organs that were preserved to be used later to treat patients, because of the time factor. Cells begin to lose capacity to carry out their vital functions, turning the organs useless.

The Russian Advanced Research Foundation has launched a scientific project aimed at developing a modern method to preserve human organs for an unlimited period of time without affecting their vital functions.

In the course of the experiments, scientists froze the heart of a frog and kept it at a temperature of -196 degrees Celsius for a month and a half, and then revived it. The post-revival tests showed that the heart was able to function vitally.

The head of the design team working on this project, Anatoly Kovtun, said that the success of these experiments would revolutionize the transfer of organs and transplant.

Finding a solution to the time challenge may help establish a "bank of frozen organs", which may save the lives of thousands of patients, he added in a press statement.



Latest Tests Show Seine Water Quality Was Substandard When Paris Mayor Took a Dip

 Boats carrying members of delegations sail along the Seine during the opening ceremony of the Paris 2024 Olympic Games on July 26, 2024. (AFP)
Boats carrying members of delegations sail along the Seine during the opening ceremony of the Paris 2024 Olympic Games on July 26, 2024. (AFP)
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Latest Tests Show Seine Water Quality Was Substandard When Paris Mayor Took a Dip

 Boats carrying members of delegations sail along the Seine during the opening ceremony of the Paris 2024 Olympic Games on July 26, 2024. (AFP)
Boats carrying members of delegations sail along the Seine during the opening ceremony of the Paris 2024 Olympic Games on July 26, 2024. (AFP)

Tests results released Friday showed the water quality in the River Seine was slightly below the standards needed to authorize swimming — just as the Paris Olympics start.

Heavy rain during the opening ceremony revived concerns over whether the long-polluted waterway will be clean enough to host swimming competitions, since water quality is deeply linked with the weather in the French capital.

Paris Mayor Anne Hidalgo took a highly publicized dip last week in a bid to ease fears. The Seine will be used for marathon swimming and triathlon.

Daily water quality tests measure levels of fecal bacteria known as E. coli.

Tests by monitoring group Eau de Paris show that at the Bras Marie, E. coli levels were then above the safe limit of 900 colony-forming units per 100 milliliters determined by European rules on June 17, when the mayor took a dip.

The site reached a value of 985 on the day the mayor swam with Paris 2024 chief Tony Estanguet and the top government official for the Paris region, Marc Guillaume, joined her, along with swimmers from local swimming clubs.

At two other measuring points further downstream, the results were below the threshold.

The statement by Paris City Hall and the prefecture of the Paris region noted that water quality last week was in line with European rules six days out of seven on the site which is to host the Olympic swimming competitions.

It noted that "the flow of the Seine is highly unstable due to regular rainfall episodes and remains more than twice the usual flow in summer," explaining fluctuating test results.

Swimming in the Seine has been banned for over a century. Since 2015, organizers have invested $1.5 billion to prepare the Seine for the Olympics and to ensure Parisians have a cleaner river after the Games. The plan included constructing a giant underground water storage basin in central Paris, renovating sewer infrastructure, and upgrading wastewater treatment plants.