Syria Labs Churn Out Anti-Malarial Drug

Rashid al-Faysal (R), the owner of a Syrian pharmaceutical factory, supervises the manufacturing process of the hydroxychloroquine drug, used in Syria to prevent or cure COVID-19, on April 28,2020 in the government controlled central city of Homs. (Photo by LOUAI BESHARA / AFP)
Rashid al-Faysal (R), the owner of a Syrian pharmaceutical factory, supervises the manufacturing process of the hydroxychloroquine drug, used in Syria to prevent or cure COVID-19, on April 28,2020 in the government controlled central city of Homs. (Photo by LOUAI BESHARA / AFP)
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Syria Labs Churn Out Anti-Malarial Drug

Rashid al-Faysal (R), the owner of a Syrian pharmaceutical factory, supervises the manufacturing process of the hydroxychloroquine drug, used in Syria to prevent or cure COVID-19, on April 28,2020 in the government controlled central city of Homs. (Photo by LOUAI BESHARA / AFP)
Rashid al-Faysal (R), the owner of a Syrian pharmaceutical factory, supervises the manufacturing process of the hydroxychloroquine drug, used in Syria to prevent or cure COVID-19, on April 28,2020 in the government controlled central city of Homs. (Photo by LOUAI BESHARA / AFP)

In central Syria, factory owner Rashid al-Faysal watches his staff working tirelessly to churn out a controversial antimalarial drug that Damascus hopes can help treat the novel coronavirus.

There is no proof yet hydroxychloroquine works to prevent or cure COVID-19, but Syrian doctors have been told to join others around the world in prescribing it for the time being.

Faysal's factory is one of several the regime has authorized to manufacture the drug, in a country with 45 official cases of COVID-19 illness, including three deaths.

On the outskirts of the central city of Homs, the pharmaceutical expert watches as a machine spurts out endless sheets of round red pills.

"We've had a permit to produce this medicine since 2016. Back then we used to produce it in really small quantities according to demand to treat illnesses such as lupus," he said, as workers busy themselves behind him.

But "demand increased hugely after the coronavirus crisis, so we imported the primary components and started to prepare it," he told Agence France Presse.

Wearing a long white lab coat, turquoise hair net, blue face mask and gloves, Faysal examines the newly produced pills.

In another room, employees in face masks sit round a table, stuffing rows of pills into small rectangular boxes.

In the past week, they have produced 12,000 boxes -- each containing 30 pills -- and plan to manufacture 40,000 more boxes in the coming days.

"That quantity covers market demand and more" if each patient is prescribed one packet, Faysal says.

There has been controversy over the drug's use to treat COVID-19, which has killed a quarter of a million people worldwide and for which no vaccine has yet been developed.

Hydroxychloroquine showed early promise against COVID-19 in small-scale studies in France and China to reduce virus levels in badly infected patients.

US President Donald Trump hailed it as a possible "gift from God" against the pandemic.

But the World Health Organization insists there is no proof hydroxychloroquine or any other drug can cure or prevent COVID-19, and that its misuse can cause serious side effects and even death.

Health ministry official Sawsan Berro says six out of 96 drug laboratories across Syria have been given licenses to produce hydroxychloroquine.

But she says synthesizing the drug is challenging in a country under Western economic sanctions over the nine-year civil war.

These measures complicate "obtaining primary materials and laboratory machine spare parts", she says.

Faysal says he initially hesitated before producing the drug, given the difficulty of importing precursor ingredients.

"We're in a country under siege," he says, referring to the economic sanctions imposed by the United States and the European Union since the start of the war in 2011.

"Financial transactions are very difficult, as are imports and exports," he says.

Faysal is reluctant to explain how he obtained the drug's components, but he described it as "the biggest risk I have ever taken in my life".

"I could have lost a lot," he says.

Syria has suspended international flights and closed its border with Lebanon to stem the pandemic.

Despite all this, the factory's quality control officer Abdelkareem Derwish hopes Syria might be able to export the medicine after meeting local demand.

"We are fully prepared to export the surplus if conditions permit," he told AFP.

In recent days, the medicine has been in such demand in Syria that a box can sell for over $100 on the black market.

But on the official market, its price has been fixed at 6,800 Syrian pounds (less than $10).

We're producing "one of the drugs most in demand in the world at the lowest prices", Derwish says.



Israel Wary of Egypt's 'Military Infrastructure' in Sinai: Peace Treaty at Risk?

Egyptian army chief Ahmed Khalifa inspects troops near Israel's border late last year. (Military spokesman)
Egyptian army chief Ahmed Khalifa inspects troops near Israel's border late last year. (Military spokesman)
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Israel Wary of Egypt's 'Military Infrastructure' in Sinai: Peace Treaty at Risk?

Egyptian army chief Ahmed Khalifa inspects troops near Israel's border late last year. (Military spokesman)
Egyptian army chief Ahmed Khalifa inspects troops near Israel's border late last year. (Military spokesman)

Israel has voiced growing concerns over Egypt’s military presence in the Sinai Peninsula, fearing a potential escalation between the two sides amid the ongoing Gaza war.

Israeli media reports said Prime Minister Benjamin Netanyahu’s government has asked both Washington and Cairo to dismantle what it describes as a “military infrastructure” established by the Egyptian army in Sinai.

However, an informed Egyptian source and experts cited by Asharq Al-Awsat insisted that Egypt has not violated its peace treaty with Israel. They argued that Cairo’s military movements are a response to Israeli breaches of the agreement.

Israel’s Israel Hayom newspaper, citing a senior Israeli security official, reported that Egypt’s military buildup in Sinai constitutes a “major violation” of the security annex of the peace treaty.

The official said the issue is a top priority for Israeli Defense Minister Israel Katz, stressing that Israel “will not accept this situation” amid what it views as Egypt’s growing military footprint in the peninsula.

The official added that the issue goes beyond the deployment of Egyptian forces in Sinai exceeding the quotas set under the military annex of the Camp David Accords.

The real concern, he said, lies in Egypt’s continued military buildup in the peninsula, which Israel views as an irreversible step.

Moreover, he stressed that while Israel is not seeking to amend its peace treaty with Egypt or redeploy troops along the border, it believes the current situation requires urgent action to prevent a potential escalation.

Egypt-Israel relations have not seen such tensions since the outbreak of the Gaza war, particularly after Israel violated a ceasefire agreement with Hamas brokered primarily by Egypt. Israeli forces resumed airstrikes on Gaza last month and failed to fulfill their commitments to withdraw from the Philadelphi Corridor and Palestinian border crossings.

A senior Egyptian source dismissed Israel’s accusations, telling Asharq Al-Awsat that “these repeated Israeli pretexts ignore the fact that Israeli forces have violated the peace treaty, seizing control of areas where Egypt objects to their presence without the necessary coordination with Cairo.”

Egypt has the right to take all necessary measures to safeguard its national security against any threats, emphasized the source.

“Nevertheless, Cairo remains fully committed to the peace treaty and has no intention of aggression against any party,” it added.

Israeli forces seized control of the Gaza-Egypt border, including the Philadelphi Corridor and the Rafah crossing, in May 2024. Israel has accused Egypt of not doing enough to stop weapons smuggling into Gaza through border tunnels—an allegation Cairo has denied.

Under the terms of the ceasefire agreement with Hamas, which Israel later broke, Israeli forces were supposed to begin withdrawing from the Philadelphi Corridor on March 1, completing the pullout within eight days. However, Israel failed to do so and instead resumed airstrikes on Gaza.

Israel also announced the creation of an administration aimed at facilitating the “voluntary departure” of Gaza residents, a move Cairo strongly rejected and formally condemned.

Egypt has insisted that Palestinians must remain in their homeland and has put forward a reconstruction plan for Gaza and called for the implementation of the two-state solution. The plan was endorsed at an emergency Arab summit three weeks ago.

Media reports have indicated that Egypt responded to Israel’s control of the Gaza border by increasing its military presence near the frontier—an act that some Israeli officials claim violates the peace treaty and threatens Israel’s security.

Former Egyptian intelligence official Gen. Mohammed Rashad told Asharq Al-Awsat that Israel itself violated the peace treaty by seizing the Philadelphi Corridor, controlling border crossings, and blocking aid to Gaza while seeking to forcibly displace Palestinians into Egypt.

“Every Israeli action along Gaza’s border with Egypt constitutes hostile behavior against Egypt’s national security,” said Rashad, who previously headed the Israeli military affairs division in Egypt’s intelligence service.

“Egypt cannot sit idly by in the face of such threats and must prepare for all possible scenarios.”

The Philadelphi Corridor is a strategically sensitive buffer zone, serving as a narrow 14-kilometer passage between Egypt, Israel, and Gaza, stretching from the Mediterranean Sea in the north to the Kerem Shalom crossing in the south.

Military expert General Samir Farag insisted that Egypt has not violated the peace treaty or its security annex in over 40 years, arguing that Israel has repeatedly breached the agreement and is attempting to shift blame onto Cairo.

“Israel is doing this to distract from its internal problems, including public discontent over its ballooning defense budget,” Farag told Asharq Al-Awsat.

“It also wants to deflect attention from Egypt’s reconstruction plan for Gaza and leverage its claims to pressure the United States for more military aid by portraying Egypt as a threat.”

Farag emphasized that Egypt’s actions are solely aimed at protecting its national security, adding: “There is no clause in the peace treaty that prevents a country from defending itself.”

“The so-called ‘military infrastructure’ Israel refers to consists of roads and development projects in Sinai.”

“The US has satellite surveillance over the region—if Egypt had violated the treaty, Washington would have flagged it. Moreover, security coordination between Egypt and Israel continues daily,” he explained.

Egypt and Israel signed their landmark peace treaty on March 25, 1979, committing to resolving disputes peacefully and prohibiting the use or threat of force. The agreement also established military deployment guidelines and a joint security coordination committee.

Meanwhile, US Republican Party member Tom Harb told Asharq Al-Awsat that Washington has received intelligence from multiple sources indicating that Egypt has amassed a significant military force in Sinai.

Israel considers this a breach of the peace treaty, which designates Sinai as a demilitarized zone to prevent surprises like the 1973 war, Harb said.

While the US fully supports Israel’s concerns, it also wants to prevent further escalation, as that would destabilize the region, he added.

Ultimately, Egypt must clarify whether its troop movements are aimed at threatening Israel or preventing Palestinians from crossing into Egyptian territory, he stated.