Scientists Devise New Method for Recovering DNA from Pharaonic Mummies

A picture taken on May 13, 2017, shows mummies lying in catacombs following their discovery in the Touna el-Gabal district of the Minya province, in central Egypt. AFP
A picture taken on May 13, 2017, shows mummies lying in catacombs following their discovery in the Touna el-Gabal district of the Minya province, in central Egypt. AFP
TT
20

Scientists Devise New Method for Recovering DNA from Pharaonic Mummies

A picture taken on May 13, 2017, shows mummies lying in catacombs following their discovery in the Touna el-Gabal district of the Minya province, in central Egypt. AFP
A picture taken on May 13, 2017, shows mummies lying in catacombs following their discovery in the Touna el-Gabal district of the Minya province, in central Egypt. AFP

Archeologists have many objections when it comes to the examination of Pharaonic mummies, and the most common one is that certain types of studies could damage the mummies. Today, a joint Italian-German study has addressed this problem. The findings will be published in the upcoming issue of the Journal of Archaeological Science in June.

According to the study's abstract published on the journal's website, researchers from the Institute for Mummy Studies at Eurac Research in Bolzano, Italy, and the Department of Orthopedics at the University of Bayreuth, Germany, announced a novel method that enables archeologists to recover DNA from mummies wrapped in linen with minimal invasion, by using CT scans and endoscopic biopsy.

The bone marrow is one of the main DNA resources in ancient mummies. But the traditional DNA recovery procedures may cause some damages, like when archeologists need to lift the linen covers. However, with CT scans, the researchers managed to determine the location of bones, and then, they conducted an endoscopic biopsy to extract a small sample of the targeted tissue.

Unlike the regular scans which require dense muscles and tissues that cannot be found in mummies, the CT scan allows archeologists to capture 3D high resolution images of the mummy. The new method uses the so-called small optical fiberscope, a thin tube equipped with a tiny camera on one end, and the eye of the fiberscope on the other end, which allows examining the structural composition inside the mummy. During the procedure, special tools are passed through the tube to extract a tiny sample of the targeted tissue.

The research team used the new method to examine a group of mummies in the Museum of Cairo, and the Egyptian Museum of Berlin.

Dr. Ayman Taher, professor of Egyptology at the Mansoura University praised the new technique that combines CT scans and small optical fiberscopes. Speaking to Asharq Al-Awsat, Taher suggested the new technique would be really useful for the examination of mummies with bad embalmment, and hoped it would help reveal more information about ancient Pharaonic diseases.

"We need to compare the characteristics of ancient diseases mentioned in the Pharaonic papyruses with the characteristics of modern diseases in order to determine their history. For instance, the worm disease was called "A'A'" in Ancient Egypt, but we don't know whether the name also refers to Bilharzia," he explained.



French Scientists Find New Blood Type in Guadeloupe Woman

A French woman from the Caribbean island of Guadeloupe has been identified as the only known carrier of a new blood type. (AFP)
A French woman from the Caribbean island of Guadeloupe has been identified as the only known carrier of a new blood type. (AFP)
TT
20

French Scientists Find New Blood Type in Guadeloupe Woman

A French woman from the Caribbean island of Guadeloupe has been identified as the only known carrier of a new blood type. (AFP)
A French woman from the Caribbean island of Guadeloupe has been identified as the only known carrier of a new blood type. (AFP)

A French woman from the Caribbean island of Guadeloupe has been identified as the only known carrier of a new blood type, dubbed "Gwada negative," France's blood supply agency has announced.

The announcement was made 15 years after researchers received a blood sample from a patient who was undergoing routine tests ahead of surgery, the French Blood Establishment (EFS) said on Friday.

"The EFS has just discovered the 48th blood group system in the world!" the agency said in a statement on social network LinkedIn.

"This discovery was officially recognized in early June in Milan by the International Society of Blood Transfusion (ISBT)."

The scientific association had until now recognized 47 blood group systems.

Thierry Peyrard, a medical biologist at the EFS involved in the discovery, told AFP that a "very unusual" antibody was first found in the patient in 2011.

However, resources at the time did not allow for further research, he added.

Scientists were finally able to unravel the mystery in 2019 thanks to "high-throughput DNA sequencing", which highlighted a genetic mutation, Peyrard said.

The patient, who was 54 at the time and lived in Paris, was undergoing routine tests before surgery when the unknown antibody was detected, Peyrard said.

This woman "is undoubtedly the only known case in the world," said the expert.

"She is the only person in the world who is compatible with herself," he said.

Peyrard said the woman inherited the blood type from her father and mother, who each had the mutated gene.

The name "Gwada negative", which refers to the patient's origins and "sounds good in all languages", has been popular with the experts, said Peyrard.

The ABO blood group system was first discovered in the early 1900s. Thanks to DNA sequencing, the discovery of new blood groups has accelerated in recent years.

Peyrard and colleagues are now hoping to find other people with the same blood group.

"Discovering new blood groups means offering patients with rare blood types a better level of care," the EFS said.