Teeth from Siberian Mammoths Yield Oldest DNA Ever Recovered

An artist's reconstruction shows the extinct steppe mammoth, an evolutionary predecessor to the woolly mammoth that flourished during the last Ice Age. (Handout via Reuters)
An artist's reconstruction shows the extinct steppe mammoth, an evolutionary predecessor to the woolly mammoth that flourished during the last Ice Age. (Handout via Reuters)
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Teeth from Siberian Mammoths Yield Oldest DNA Ever Recovered

An artist's reconstruction shows the extinct steppe mammoth, an evolutionary predecessor to the woolly mammoth that flourished during the last Ice Age. (Handout via Reuters)
An artist's reconstruction shows the extinct steppe mammoth, an evolutionary predecessor to the woolly mammoth that flourished during the last Ice Age. (Handout via Reuters)

Scientists have recovered the oldest DNA on record, extracting it from the molars of mammoths that roamed northeastern Siberia up to 1.2 million years ago in research that broadens the horizons for understanding extinct species.

The researchers said on Wednesday they had recovered and sequenced DNA from the remains of three individual mammoths - elephant cousins that were among the large mammals that dominated Ice Age landscapes - entombed in permafrost conditions conducive to preservation of ancient genetic material.

While the remains were discovered starting in the 1970s, new scientific methods were needed to extract the DNA.

The oldest of the three, discovered near the Krestovka river, was approximately 1.2 million years old. Another, from near the Adycha river, was approximately 1 to 1.2 million years old. The third, from near the Chukochya river, was roughly 700,000 years old.

“This is by a wide margin the oldest DNA ever recovered,” said evolutionary geneticist Love Dalén of the Centre for Palaeogenetics in Sweden, who led the research published in the journal Nature.

Until now, the oldest DNA came from a horse that lived in Canada’s Yukon territory about 700,000 years ago. By way of comparison, our species, Homo sapiens, first appeared roughly 300,000 years ago.

DNA is the self-replicating material that carries genetic information in living organisms - sort of a blueprint of life.

“This DNA was extremely degraded into very small pieces, and so we had to sequence many billions of ultra-short DNA sequences in order to puzzle these genomes together,” Dalén said.

Most knowledge about prehistoric creatures comes from studying skeletal fossils, but there is a limit to what these can tell about an organism, particularly relating to genetic relationships and traits.

Ancient DNA can help fill in the blanks but is highly perishable. Sophisticated new research techniques are enabling scientists to recover ever-older DNA.

“It would be a wild guess, but a maximum of two to three million years should be doable,” Dalén said.

That could shed light on some bygone species but would leave many others unattainable - including the dinosaurs, who went extinct 66 million years ago.

“When we can get DNA on a million-year time scale, we can study the process of speciation (formation of new species) in a much more detailed way. Morphological analyses on bones and teeth usually only allow researchers to study a handful of characteristics in the fossils, whereas with genomics we are analyzing many tens of thousands of characteristics,” Dalén said.

The researchers gained insights into mammoth evolution and migration by comparing the DNA to that of mammoths that lived more recently. The last mammoths disappeared roughly 4,000 years ago.

The oldest of the three specimens, the Krestovka mammoth, belonged to a previously unknown genetic lineage that more than 2 million years ago diverged from the lineage that led to the well-known woolly mammoth.

Geneticist Tom van der Valk of SciLifeLab in Sweden, the study’s first author, said it appears that members of the Krestovka lineage were the first mammoths to migrate from Siberia into North America over a now-disappeared land bridge about 1.5 million years ago, with woolly mammoths later migrating about 400,000 to 500,000 years ago.

The Adycha mammoth’s lineage apparently was ancestral to the woolly mammoth, they found, and the Chukochya individual is one of the oldest-known woolly mammoth specimens.

DNA analyses showed that genetic variants associated with enduring frigid climes such as hair growth, thermoregulation, fat deposits, cold tolerance and circadian rhythms were present long before the origin of the woolly mammoth.



Hungary's Oldest Library is Fighting to Save Books from Beetle Infestation

Books are kept in hermetically sealed plastic sacks for disinfection at the Pannonhalma Archabbey's library in Pannonhalma, Hungary, Thursday, July 3, 2025, as a beetle infestation threatens its ancient collection. (AP Photo/Bela Szandelszky)
Books are kept in hermetically sealed plastic sacks for disinfection at the Pannonhalma Archabbey's library in Pannonhalma, Hungary, Thursday, July 3, 2025, as a beetle infestation threatens its ancient collection. (AP Photo/Bela Szandelszky)
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Hungary's Oldest Library is Fighting to Save Books from Beetle Infestation

Books are kept in hermetically sealed plastic sacks for disinfection at the Pannonhalma Archabbey's library in Pannonhalma, Hungary, Thursday, July 3, 2025, as a beetle infestation threatens its ancient collection. (AP Photo/Bela Szandelszky)
Books are kept in hermetically sealed plastic sacks for disinfection at the Pannonhalma Archabbey's library in Pannonhalma, Hungary, Thursday, July 3, 2025, as a beetle infestation threatens its ancient collection. (AP Photo/Bela Szandelszky)

Tens of thousands of centuries-old books are being pulled from the shelves of a medieval abbey in Hungary in an effort to save them from a beetle infestation that could wipe out centuries of history.

The 1,000-year-old Pannonhalma Archabbey is a sprawling Benedictine monastery that is one of Hungary's oldest centers of learning and a UNESCO World Heritage site.

Restoration workers are removing about 100,000 handbound books from their shelves and carefully placing them in crates, the start of a disinfection process that aims to kill the tiny beetles burrowed into them, The Associated Press reported.

The drugstore beetle, also known as the bread beetle, is often found among dried foodstuffs like grains, flour and spices. But they also are attracted to the gelatin and starch-based adhesives found in books.

They have been found in a section of the library housing around a quarter of the abbey's 400,000 volumes.

“This is an advanced insect infestation which has been detected in several parts of the library, so the entire collection is classified as infected and must be treated all at the same time,” said Zsófia Edit Hajdu, the chief restorer on the project. “We've never encountered such a degree of infection before.”

The beetle invasion was first detected during a routine library cleaning.

Employees noticed unusual layers of dust on the shelves and then saw that holes had been burrowed into some of the book spines. Upon opening the volumes, burrow holes could be seen in the paper where the beetles chewed through.

The abbey at Pannonhalma was founded in 996, four years before the establishment of the Kingdom of Hungary. Sitting upon a tall hill in northwestern Hungary, the abbey houses the country's oldest collection of books, as well as many of its earliest and most important written records.

For over 1,000 years, the abbey has been among the most prominent religious and cultural sites in Hungary and all of Central Europe, surviving centuries of wars and foreign incursions such as the Ottoman invasion and occupation of Hungary in the 16th century.

Ilona Ásványi, director of the Pannonhalma Archabbey library, said she is “humbled” by the historical and cultural treasures the collection holds whenever she enters.

“It is dizzying to think that there was a library here a thousand years ago, and that we are the keepers of the first book catalogue in Hungary,” she said.

Among the library’s most outstanding works are 19 codices, including a complete Bible from the 13th century. It also houses several hundred manuscripts predating the invention of the printing press in the mid-15th century and tens of thousands of books from the 16th century.

While the oldest and rarest prints and books are stored separately and have not been infected, Ásványi said any damage to the collection represents a blow to cultural, historical and religious heritage.

“When I see a book chewed up by a beetle or infected in any other way, I feel that no matter how many copies are published and how replaceable the book is, a piece of culture has been lost,” she said.

To kill the beetles, the crates of books are being placed into tall, hermetically sealed plastic sacks from which all oxygen is removed. After six weeks in the pure nitrogen environment, the abbey hopes all the beetles will be destroyed.

Before being reshelved, each book will be individually inspected and vacuumed. Any book damaged by the pests will be set aside for later restoration work.

The abbey, which hopes to reopen the library at the beginning of next year, believes the effects of climate change played a role in spurring the beetle infestation as average temperatures rise rapidly in Hungary.

Hajdu, the chief restorer, said higher temperatures have allowed the beetles to undergo several more development cycles annually than they could in cooler weather.

“Higher temperatures are favorable for the life of insects,” she said. “So far we've mostly dealt with mold damage in both depositories and in open collections. But now I think more and more insect infestations will appear due to global warming.”

The library’s director said life in a Benedictine abbey is governed by a set of rules in use for nearly 15 centuries, a code that obliges them to do everything possible to save its vast collection.

“It says in the Rule of Saint Benedict that all the property of the monastery should be considered as of the same value as the sacred vessel of the altar,” Ásványi said. “I feel the responsibility of what this preservation and conservation really means.”