Study: Coffee Reduces Risk of Liver Disease

Stenophylla coffee is prepared for tasting at the French Agricultural Research Centre for International Development (CIRAD) lab in Montpellier, France in December 2020. Photo: CIRAD via AFP
Stenophylla coffee is prepared for tasting at the French Agricultural Research Centre for International Development (CIRAD) lab in Montpellier, France in December 2020. Photo: CIRAD via AFP
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Study: Coffee Reduces Risk of Liver Disease

Stenophylla coffee is prepared for tasting at the French Agricultural Research Centre for International Development (CIRAD) lab in Montpellier, France in December 2020. Photo: CIRAD via AFP
Stenophylla coffee is prepared for tasting at the French Agricultural Research Centre for International Development (CIRAD) lab in Montpellier, France in December 2020. Photo: CIRAD via AFP

Coffee drinkers may be protected against liver problems in later life. They have a 21 percent lower risk of developing chronic liver disease than non-coffee drinkers, say researchers who studied the medical histories and coffee consumption of half a million Britons.

The drink contains compounds called kahweol and cafestol which are thought to dampen down inflammation which can damage the liver. The compounds are at higher levels in ground coffee, The Daily Mail reported.

Caffeine, meanwhile, is believed to combat harmful liver scarring.

Dr. Oliver Kennedy, author of the study published in the journal BMC Public Health from the University of Southampton, said: "Coffee is widely accessible and the benefits we see may mean it could offer a potential preventative treatment."

One in three Britons are thought to have early non-alcoholic fatty liver disease. It is more common in the overweight, according to the German News Agency. It can lead to chronic liver disease if it gets worse.

Chronic liver disease can also be caused by excessive drinking, and viral hepatitis. But researchers found coffee appears to ward off the serious condition, with those who drink it regularly 49 percent less likely to die from chronic liver disease than non-coffee drinkers.

The study, published in the journal BMC Public Health, looked at 494,585 people aged 40 to 69 from the UK Biobank study. More than three-quarters were regular coffee drinkers, averaging two cups a day.

Compared to non-coffee drinkers, those who drank coffee had a 21 percent lower risk of developing chronic liver disease and a reduced risk of the most common type of liver cancer.



Scientists: Ancient Jawbone from Taiwan Belongs to Mysterious Group of Human Ancestors

This illustration provided by researchers in April 2025 depicts a Denisovan male in Taiwan in the Pleistocene era about 2.6 million to 11,700 years ago. (Cheng-Han Sun via AP)
This illustration provided by researchers in April 2025 depicts a Denisovan male in Taiwan in the Pleistocene era about 2.6 million to 11,700 years ago. (Cheng-Han Sun via AP)
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Scientists: Ancient Jawbone from Taiwan Belongs to Mysterious Group of Human Ancestors

This illustration provided by researchers in April 2025 depicts a Denisovan male in Taiwan in the Pleistocene era about 2.6 million to 11,700 years ago. (Cheng-Han Sun via AP)
This illustration provided by researchers in April 2025 depicts a Denisovan male in Taiwan in the Pleistocene era about 2.6 million to 11,700 years ago. (Cheng-Han Sun via AP)

An ancient jawbone discovered in Taiwan belonged to an enigmatic group of early human ancestors called Denisovans, scientists reported Thursday.
Relatively little is known about Denisovans, an extinct group of human cousins that interacted with Neanderthals and our own species, Homo sapiens.
“Denisovan fossils are very scarce,” with only a few confirmed finds in East Asia, said study co-author Takumi Tsutaya at the Graduate University for Advanced Studies in Japan.
So far, the only known Denisovan fossils include partial jawbones, a few teeth and part of a finger bone found in caves in Siberia and Tibet. Some scientists believe fossils found in a cave in Laos may also belong to Denisovans, The Associated Press reported.
The probable identification of the jawbone from Taiwan as Denisovan expands the region where scientists know these ancient people once lived, said Tsutaya.
The partial jawbone was first recovered when a fishing operation dredged the seafloor in the Penghu Channel near the Taiwan Strait. After it was sold to an antique shop, a collector spotted it and purchased it in 2008, then later donated it to Taiwan’s National Museum of Natural Science.
Based on the composition of marine invertebrates found attached to it, the fossil was dated to the Pleistocene era. But exactly which species of early human ancestor it belonged to remained a mystery.
The condition of the fossil made it impossible to study ancient DNA. But recently, scientists in Taiwan, Japan and Denmark were able to extract some protein sequences from the incomplete jawbone.
An analysis showed some protein sequences resembled those contained in the genome of a Denisovan fossil recovered in Siberia. The findings were published in the journal Science.
While the new research is promising, Rick Potts, director of the Smithsonian Institution’s Human Origins Project, said he would like to see further data before confirming the Taiwan fossil as Denisovan.
Potts, who was not involved in the new research, praised the study for “a fantastic job of recovering some proteins.” But he added, such a small sliver of material may not give a full picture.
At one time, at least three human ancestor groups — Denisovans, Neanderthals and Homo sapiens — coexisted in Eurasia and sometimes interbred, researchers say.
“We can identity Neanderthal elements and Denisovan elements" in the DNA of some people alive today, said Tsutaya.