Magical Effects of Psychedelics Can Transform Psychiatry

Illustrative Ecstasy pills. (AP)
Illustrative Ecstasy pills. (AP)
TT
20

Magical Effects of Psychedelics Can Transform Psychiatry

Illustrative Ecstasy pills. (AP)
Illustrative Ecstasy pills. (AP)

Imagine a medicine that could help people process disturbing memories, sparking behavioral changes rather than merely burying and suppressing symptoms and trauma. For the millions suffering with post-traumatic stress disorder (PTSD) and depression, such remedies for their daily struggles could be on the horizon. Psychiatry is rapidly heading towards a new frontier – and it's all thanks to psychedelics, The Guardian reported.

In an advanced phase trial published in Nature in May, patients in the US, Israel and Canada who received doses of the psychedelic stimulant Ecstasy (MDMA), alongside care from a therapist, were more than twice as likely as the placebo group to no longer have PTSD - for which there is currently no effective treatment - months later.

The researchers concluded that the findings, which reflected those of six earlier-stage trials, cemented the treatment as a startlingly successful potential breakthrough therapy. There are now hopes that MDMA therapy could receive approval for certain treatments from US regulators by 2023, or perhaps even earlier – with psilocybin, the active ingredient of magic mushrooms, not far behind in the process. A small study at Johns Hopkins University, published last year, suggested it could be four times more effective than traditional antidepressants.

You could say interest in psychedelics is mushrooming. Last month, in a first for psychedelics since the war on drugs was launched in the 1970s, US federal funding was granted for a psilocybin study to treat tobacco addiction following pressure by lawmakers, including Alexandria Ocasio-Cortez.

This marks a jaw-dropping turnaround for hallucinogenic drugs. Even 10 years ago, they were effectively taboo in many academic fields and halls of power. But as the intellectual rationale behind the war on drugs has become increasingly untenable, hundreds of millions of dollars have been pumped into psychedelic pharmaceutical research.



Heartbroken Brits Abandon Pets as Living Costs Bite

Rising numbers of pets are being left at the Mayhew shelter in London as owners no longer able to afford their care take the heartbreaking decision to try to re-home them. Ben STANSALL / AFP
Rising numbers of pets are being left at the Mayhew shelter in London as owners no longer able to afford their care take the heartbreaking decision to try to re-home them. Ben STANSALL / AFP
TT
20

Heartbroken Brits Abandon Pets as Living Costs Bite

Rising numbers of pets are being left at the Mayhew shelter in London as owners no longer able to afford their care take the heartbreaking decision to try to re-home them. Ben STANSALL / AFP
Rising numbers of pets are being left at the Mayhew shelter in London as owners no longer able to afford their care take the heartbreaking decision to try to re-home them. Ben STANSALL / AFP

Staff at a London animal shelter have seen more than their fair share of abandoned pets over the years, from kittens in boxes to budgies dropped outside in the dead of night.
But lately there has been a surge in the numbers as people make the heartbreaking decision to give up their animal companions, no longer able to afford to care for their pets.

Struggling animal owners are feeling "a lot of heartache... and also shame and frustration that they're having to make these decisions," said Elvira Meucci-Lyons, the boss of the Mayhew shelter in Kensal Green, west London.

"They come to us because they feel they have no choice," she said.

"Behind every animal we take in there's a human story."

The small center has taken in more than 130 animals this year alone. It is part of a wider rise across the UK, where tens of thousands of pets have been abandoned since the Covid-19 pandemic and the onset of a cost-of-living crisis.

In the first few months of this year, more than 5,700 abandonments have been reported to the RSPCA, the world's oldest animal welfare organization -- a 32 percent rise on the same period in 2024.

Last year saw around 22,500 cases reported in total, up more than seven percent on 2023.
The challenge of affording animal care poses a heart-wrenching problem for many in Britain, a nation of dog and cat lovers where half the adult population -- more than 26 million people -- has a pet, according to the RSPCA.

And it has hit the country's poorest especially hard. Staff at Mayhew said some owners were having to choose between feeding themselves or their pets.

Several pets at the center -- including dogs Brownie, a one-year-old toy poodle, and Astro, a pocket American bully -- were brought in because their owners lost their homes due to financial troubles.

Stories like these are "the most upsetting", Meucci-Lyons said, because in hard times pet owners "need their lovely animals more than ever and the dog or cat doesn't want to do without their owner."

Rising vet bills
Mayhew staff said more pets were also arriving at the center in Kensal Green in poor health, often because their owners cannot afford veterinary bills.

Felix's case is typical. The muscular nine-year-old tomcat was playing with a length of string. But he arrived with tooth problems, with his owners bringing him to the shelter and saying they couldn't afford to keep him.
"We're seeing quite a lot more needing dental work nowadays," said Mayhew spokeswoman Olivia Patt.

The pandemic saw a spike in pet ownership under government lockdowns, and a subsequent wave of people then giving up their animals as normal lifestyles resumed.

Some people are returning lockdown pets, several years on. But RSPCA spokesman David Bowles told AFP that living costs, which soared during the pandemic, have become a major factor driving abandonments.

"We are now five years on from the first lockdown under Covid. The RSPCA believes the cost-of-living crisis is really impacting people's ability to pay for vet treatment in particular," he said.

UK inflation soared above 11 percent in October 2022, the highest level in more than four decades, and while it has slowed in the last few years, people are still feeling the squeeze.

Prices for many items including pet food have gone up by around 25 percent.
At Mayhew, staff have been doing all they can, from providing struggling owners with pet food and animal care packages, to offering free preventative treatments.

But the pressure has pushed the shelter's bubbly staff to their limits.

"We are run off our feet, we can't keep up with the demand," said Meucci-Lyons.

Even though the staff are comforted by knowing they make a difference, "every day it is heartbreaking -- we go to bed at night thinking about the dogs and cats we can't help," she said.