Rapid Testing for Omicron: Is a Nose Swab Enough?

A health worker in personal protective equipment (PPE) takes a swab sample from a police officer for a rapid antigen test amid the coronavirus disease (COVID-19) outbreak, in Bangkok, Thailand, January 7, 2022. (Reuters)
A health worker in personal protective equipment (PPE) takes a swab sample from a police officer for a rapid antigen test amid the coronavirus disease (COVID-19) outbreak, in Bangkok, Thailand, January 7, 2022. (Reuters)
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Rapid Testing for Omicron: Is a Nose Swab Enough?

A health worker in personal protective equipment (PPE) takes a swab sample from a police officer for a rapid antigen test amid the coronavirus disease (COVID-19) outbreak, in Bangkok, Thailand, January 7, 2022. (Reuters)
A health worker in personal protective equipment (PPE) takes a swab sample from a police officer for a rapid antigen test amid the coronavirus disease (COVID-19) outbreak, in Bangkok, Thailand, January 7, 2022. (Reuters)

The fast-spreading Omicron variant has made us more reliant on rapid at-home antigen tests to tell us if we have COVID-19. But should we be swabbing our throats as well as our noses?

For now, the guidance depends on where you live.

Some scientists have said people can transmit Omicron when it has infected their throat and saliva but before the virus has reached their noses, so swabbing the nostrils early in the infection will not pick it up.

A small recent US study backed up that view. PCR tests of the saliva from 29 people infected with Omicron detected the virus on average three days before nose samples were positive in antigen, or so-called lateral flow, tests.

In general, rapid tests have a lower sensitivity than lab-processed PCR tests, meaning they produce more false negatives. But if you test positive, you almost certainly have COVID-19, making antigen tests a powerful tool in tackling the pandemic as demand for PCR tests due to Omicron overwhelms laboratories.

As a result of recent studies, some experts in the United States have now advised antigen test users should swab the throat before swabbing the nose.

All the antigen tests with emergency use authorizations from the US Food and Drug Administration use nasal samples and it has expressed concerns over the safety of throat swabbing at home, saying users should follow manufacturers' instructions.

In Israel, a top health official has said people self-testing for COVID-19 should swab their throat as well as their nose when using rapid antigen tests, even if it goes against instructions issued by the manufacturer.

Some other countries, including the United Kingdom, have approved rapid antigen tests that swab both the throat and nose, or just the nose.

In Germany, the minister for health has said they will study how reliable rapid antigen tests are in detecting the Omicron variant and publish a list of the most accurate products.



Cologne Starts Its Biggest Evacuation Since 1945 To Defuse WWII Bombs 

One of the three unexploded bombs from the Second World War is fenced off with screens as specialists prepare to defuse them in Cologne, Tuesday, June 3, 2025. (Thomas Banneyer/dpa via AP)
One of the three unexploded bombs from the Second World War is fenced off with screens as specialists prepare to defuse them in Cologne, Tuesday, June 3, 2025. (Thomas Banneyer/dpa via AP)
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Cologne Starts Its Biggest Evacuation Since 1945 To Defuse WWII Bombs 

One of the three unexploded bombs from the Second World War is fenced off with screens as specialists prepare to defuse them in Cologne, Tuesday, June 3, 2025. (Thomas Banneyer/dpa via AP)
One of the three unexploded bombs from the Second World War is fenced off with screens as specialists prepare to defuse them in Cologne, Tuesday, June 3, 2025. (Thomas Banneyer/dpa via AP)

More than 20,000 residents were being evacuated from part of Cologne's city center on Wednesday as specialists prepared to defuse three unexploded US bombs from World War II that were unearthed earlier this week.

Even 80 years after the end of the war, unexploded bombs dropped during wartime air raids are frequently found in Germany.

Disposing of them sometimes entails large-scale precautionary evacuations such as the one on Wednesday, though the location this time was unusually prominent and this is Cologne's biggest evacuation since 1945. There have been bigger evacuations in other cities.

Authorities on Wednesday morning started evacuating about 20,500 residents from an area within a 1,000-meter (3,280-foot) radius of the bombs, which were discovered on Monday during preparatory work for road construction. They were found in the Deutz district, just across the Rhine River from Cologne's historic center.

As well as homes, the area includes 58 hotels, nine schools, several museums and office buildings and the Messe/Deutz train station.

It also includes three bridges across the Rhine, among them the heavily used Hohenzollern railway bridge, which leads into Cologne's central station and is being shut during the defusal work itself.

Shipping on the Rhine will also be suspended.

The plan is for the bombs to be defused during the course of the day. When exactly that happens depends on how long it takes for authorities to be sure that everyone is out of the evacuation zone.