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Remotely Heated Seeds to Treat Brain Tumors

A tumor seen on an MRI scan. (Getty/iStock)
A tumor seen on an MRI scan. (Getty/iStock)
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Remotely Heated Seeds to Treat Brain Tumors

A tumor seen on an MRI scan. (Getty/iStock)
A tumor seen on an MRI scan. (Getty/iStock)

A tiny magnetic seed could hold the key to treating tumors in some of the most inaccessible parts of the body. According to Sky News, minimally invasive image-guided ablation, or "Minima", is a new therapy which sees the 2mm seed guided through the brain to heat and destroy tumors.

Tested on mice, it involves using an MRI scanner to navigate the seed's path to the tumor, before heating it remotely and using this heat to kill off the cancer cells. The technique could mean more effective treatment, reduced recovery times, and less chance of side effects.

It could be used against hard-to-reach glioblastoma - the most common form of brain cancer - as well as prostate cancer and other tumors that would benefit from less invasive treatment. The findings are detailed in a study published in the journal Advanced Science. Senior author, Professor Mark Lythgoe from the UCL Centre for Advanced Biomedical Imaging, told the PA news agency: "By having precise remote control of the seed using the MRI scanner, we can destroy only the cancer cells. This means that we will be able to preserve the healthy tissue.”

"In terms of neurosurgery this means that we will be able to preserve motor function and cognitive function which not only contribute to the quality of life and recovery time but can contribute to the long-term survival of the patient," he added.

Co-author Dr. Lewis Thorne is a consultant neurosurgeon at the National Hospital for Neurology and Neurosurgery who treats patients with glioblastoma.

"Minima can successfully destroy cancer in a mouse and has the potential to extend survival and limit damage to adjacent brain tissues in patients," Lythgoe added.
Professor Mark Emberton, UCL Division of Surgery and Interventional Science - lead cancer clinician in the study, said: "Improving the precision of our cancer treatments is arguably one of the greatest unmet needs we have today. "

One in eight men will be diagnosed with prostate cancer.

"While treatments such as radiotherapy and surgery can be effective, they often cause unwanted and debilitating side effects such as incontinence and impotence. Minima may allow us to precisely target and destroy prostate tumor tissue, reducing harm to normal cells,” Emberton concluded.

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Zoo in Spain Helps Elderly Elephants Age Gracefully

Two old African elephants Bully, left, and Susi, stand inside the Barcelona Zoo in Spain, Thursday, March 27, 2025. (AP Photo/Hernan Muñoz)
Two old African elephants Bully, left, and Susi, stand inside the Barcelona Zoo in Spain, Thursday, March 27, 2025. (AP Photo/Hernan Muñoz)
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Zoo in Spain Helps Elderly Elephants Age Gracefully

Two old African elephants Bully, left, and Susi, stand inside the Barcelona Zoo in Spain, Thursday, March 27, 2025. (AP Photo/Hernan Muñoz)
Two old African elephants Bully, left, and Susi, stand inside the Barcelona Zoo in Spain, Thursday, March 27, 2025. (AP Photo/Hernan Muñoz)

At the Barcelona Zoo, a 40-year-old African elephant places her foot through the metal barrier where a zookeeper gently scrubs its sole — the beloved pachyderm gets her “pedicure,” along with apple slices every day.
The treatment is part of the zoo’s specialized geriatric care for aging animals that cannot be reintroduced into the wild as zoos world over increasingly emphasize lifelong care, The Associated Press reported.
“Sending them back into nature would be an error," said Pilar Padilla, head of the zoo's mammal care. "It is very likely they wouldn’t survive.”
Zoos have undergone a rethink in recent decades with the emphasis on the conservation of species and education, moving away from the past paradigm that often displayed exotic animals as a spectacle.
The new approach includes knowing how to adapt to the needs of aging animals, which has led zoos to create bigger, more nature-like enclosures, such as the Sahel-Savannah area at the zoo in the Spanish city of Barcelona.
Along with breeding programs to reintroduce fit animals into nature, zoos today want to ensure that animals living longer due to advancements in veterinary care can age gracefully, said Martín Zordan, the CEO of the World Association of Zoos and Aquariums, or WAZA.
“Specialized geriatric care is becoming increasingly essential," Zordan told AP at the organization’s Barcelona offices.
Zordan said that just like older people, elderly animals require more care: regular health checks, arthritis treatment, softer foods or nutritional supplements, adapted living spaces and monitoring of mental and behavioral health.
Along with caring for a pair of aging elephants, the Barcelona Zoo is also the home for a 15-year-old wolf, a leopard and a tiger who are both 17, as well as some older birds — including a flock of senior flamencos.
It's not alone — several zoos in the United States, for example, highlight their treatment of older animals, such as the zoos in Baltimore and Baton Rouge.
A study of grief Zookeepers at the Barcelona Zoo, not far from the city’s Mediterranean coastline, are closely monitoring its two aging female pachyderms, Susi and Bully (pronounced BUH'-yi), as they cope with the recent death of Yoyo, their former pen-mate and long-time companion.
Yoyo died in December at age 54.
Susi, at 52, is now among the oldest known African elephants in captivity, even though WAZA said the age of animals born in the wild is approximate. Bully, who is 40, is also considered old for an African elephant. All three were captured in the wild and spent time in circuses an other zoos before coming to Barcelona.
The zoo is now working with the University of Barcelona to study the impact of Yoyo's death on Susi and Bully. It’s the first study of its kind, focused on elephants not from the same family after the death of a long-time companion, Padilla told The Associated Press during a recent visit to the zoo’s elephant enclosure.
At first, Susi and Bully showed their shock by not eating, but are now adapting well and turning to one another, including even sharing food, Padilla said, adding that Susi has taken on the dominant role that Yoyo had.
The proof is in the teeth For elephants, their teeth are the real age test.
“What marks the decline of the animal is the wear on their teeth,” Barcelona zookeeper José María Santamaría said after finishing the Bully’s pedicure. “They go through six sets of molars during their life, and when they reach around 40 years old they lose the last set.”
Susi and Bully require daily checkups, food suited for their now molar-less mouths and extra attention to their legs — hence the daily pedicures and the enclosure's soft sandy floor to cushion aching feet.
“Those are the sort of considerations taken because we care about these animals living comfortably and leading lives with dignity,” Zordan said.