عربي English Türkçe اردو فارسى
Logo
Latest News
Varieties

Discovery of Prostate Cancer Linked-Bacteria Could Pave Way for Treatment

Scientists work at a laboratory south of Cambridge, Britain, March 12, 2021. (Reuters)
Scientists work at a laboratory south of Cambridge, Britain, March 12, 2021. (Reuters)
TT
TT

Discovery of Prostate Cancer Linked-Bacteria Could Pave Way for Treatment

Scientists work at a laboratory south of Cambridge, Britain, March 12, 2021. (Reuters)
Scientists work at a laboratory south of Cambridge, Britain, March 12, 2021. (Reuters)

Scientists have discovered bacteria linked to aggressive prostate cancer in work hailed as a potential revolution for the prevention and treatment of the disease, reported The Guardian.

Researchers led by the University of East Anglia performed sophisticated genetic analyses on the urine and prostate tissue of more than 600 men with and without prostate cancer and found five species of bacteria linked to rapid progression of the disease.

The study does not prove that the bacteria drive or exacerbate prostate cancer, but if work now under way confirms their role, researchers can develop tests to identify men most at risk and potentially find antibiotics to prevent the cancer from claiming thousands of lives each year.

“This is an exciting discovery that has the potential to truly revolutionize treatment for men,” said Dr. Hayley Luxton of Prostate Cancer UK, which co-funded the research.

Writing in the journal European Urology Oncology, the scientists describe how their genetic investigations found five species of bacteria – three new to science – that were associated with advanced prostate cancer. Men who had one or more of the species in their urine, prostate or tumor tissue were 2.6 times more likely to see their early-stage cancer progress to advanced disease than men who did not.

Lead scientist Colin Cooper, a professor of cancer genetics at the University of East Anglia, said it was possible the bacteria are not involved in the disease. For example, men with more aggressive prostate cancer may have immune system deficiencies that allow certain bacteria to thrive.

Most Viewed

 
 
Varieties

Muddy Footprints Suggest 2 Species of Early Humans Were Neighbors in Kenya 1.5 Million Years Ago

An aerial view shows a research team standing alongside the fossil footprint trackway at the excavation site on the eastern side of Lake Turkana in northern Kenya in 2022. AP
An aerial view shows a research team standing alongside the fossil footprint trackway at the excavation site on the eastern side of Lake Turkana in northern Kenya in 2022. AP
TT
TT

Muddy Footprints Suggest 2 Species of Early Humans Were Neighbors in Kenya 1.5 Million Years Ago

An aerial view shows a research team standing alongside the fossil footprint trackway at the excavation site on the eastern side of Lake Turkana in northern Kenya in 2022. AP
An aerial view shows a research team standing alongside the fossil footprint trackway at the excavation site on the eastern side of Lake Turkana in northern Kenya in 2022. AP

Muddy footprints left on a Kenyan lakeside suggest two of our early human ancestors were nearby neighbors some 1.5 million years ago.
The footprints were left in the mud by two different species “within a matter of hours, or at most days,” said paleontologist Louise Leakey, co-author of the research published Thursday in the journal Science.
Scientists previously knew from fossil remains that these two extinct branches of the human evolutionary tree – called Homo erectus and Paranthropus boisei – lived about the same time in the Turkana Basin.
But dating fossils is not exact. “It’s plus or minus a few thousand years,” said paleontologist William Harcourt-Smith of Lehman College and the American Museum of Natural History in New York, who was not involved in the study.
Yet with fossil footprints, “there’s an actual moment in time preserved,” he said. “It’s an amazing discovery.”
The tracks of fossil footprints were uncovered in 2021 in what is today Koobi Fora, Kenya, said Leaky, who is based at New York's Stony Brook University.
Whether the two individuals passed by the eastern side of Lake Turkana at the same time – or a day or two apart – they likely knew of each other’s existence, said study co-author Kevin Hatala, a paleoanthropologist at Chatham University in Pittsburgh.
“They probably saw each other, probably knew each other was there and probably influenced each other in some way,” The Associated Press quoted him as saying.
Scientists were able to distinguish between the two species because of the shape of the footprints, which holds clues to the anatomy of the foot and how it’s being used.
H. erectus appeared to be walking similar to how modern humans walk – striking the ground heel first, then rolling weight over the ball of the foot and toes and pushing off again.
The other species, which was also walking upright, was moving “in a different way from anything else we’ve seen before, anywhere else,” said co-author Erin Marie Williams-Hatala, a human evolutionary anatomist at Chatham.
Among other details, the footprints suggest more mobility in their big toe, compared to H. erectus or modern humans, said Hatala.
Our common primate ancestors probably had hands and feet adapted for grasping branches, but over time the feet of human ancestors evolved to enable walking upright, researchers say.
The new study adds to a growing body of research that implies this transformation to bipedalism – walking on two feet — didn’t happen at a single moment, in a single way.
Rather, there may have been a variety of ways that early humans learned to walk, run, stumble and slide on prehistoric muddy slopes.
“It turns out, there are different gait mechanics – different ways of being bipedal,” said Harcourt-Smith.