Turks Look to History and Foresee Rebirth of Ancient Antakya from Earthquake Ruins

The destroyed Habib-i Najjar Mosque is pictured in the aftermath of a deadly earthquake in Antakya, Türkiye, February 16, 2023. (Reuters)
The destroyed Habib-i Najjar Mosque is pictured in the aftermath of a deadly earthquake in Antakya, Türkiye, February 16, 2023. (Reuters)
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Turks Look to History and Foresee Rebirth of Ancient Antakya from Earthquake Ruins

The destroyed Habib-i Najjar Mosque is pictured in the aftermath of a deadly earthquake in Antakya, Türkiye, February 16, 2023. (Reuters)
The destroyed Habib-i Najjar Mosque is pictured in the aftermath of a deadly earthquake in Antakya, Türkiye, February 16, 2023. (Reuters)

Remnants of ancient Abrahamic history were destroyed when an earthquake flattened much of Antakya in southern Türkiye last month, but many hope the city can rise from the rubble as it has done over centuries of disasters and conquests.

Established by the Seleucid Empire in 300 BC, Antakya, formerly Antioch, has been home to Jews, Christians and Muslims and destroyed or heavily damaged several times as it changed hands between Greeks, Romans, Arabs and Ottomans.

Much of the rescue effort after the Feb. 6 earthquakes focused on the modern, residential side of Antakya, where thousands were caught in their sleep and crushed or trapped under the rubble. In total, nearly 52,000 people were killed in Türkiye and Syria.

On the opposite bank of the Orontes River, in the old town once popular with tourists, mosques and churches lie ruined. Rescue efforts in the area, populated with businesses rather than homes, were sparse, while security forces kept guard against looters at every corner.

Abdurrahman Kurdo, a business student and the manager of a hotel near the destroyed Antioch Greek Orthodox Church, was sifting through the rubble to salvage what he could of Antakya's culture. So far he had found an issue of Hatay Magazine, celebrating life in Türkiye’s southernmost province, from the 1970s.

"The rubble in this area is not only made up of concrete piles, rocks and roof tiles - the culture of Hatay lies underneath," he said.

"What we learn from our elders is that Hatay witnessed seven earthquakes in its history but it was reborn from its ashes. We believe that Hatay will be reborn from its ashes again."

The entrance to the courtyard of the church, rebuilt after an earthquake in 1872, can now only be accessed from a side street by climbing over a mound of debris.

Habib-i Najjar Mosque

The bell tower lies on its side, with clothes placed on top for earthquake victims to take. From the courtyard, the entrance to the church is barely recognizable, the door hidden behind rubble.

The floor is also covered by rubble from the collapsed roof, while several paintings of Jesus and the saints hang slanted and covered in dust and mud on the walls. Others lie among the debris.

The Habib-i Najjar Mosque, said to be the first mosque in the Anatolia peninsula, dates back to the Roman Empire, when it is believed there was a pagan temple in its place. A church built in its place was turned into a mosque and then back to a church, a pattern repeating itself several times. It was last rebuilt by the Ottoman Empire in the 1800s after an earthquake.

The minaret collapsed in last month's disaster and only a small section of the dome above the pulpit can be seen behind the rubble of the front wall that fell into the courtyard, while three other walls appear intact.

The Ulu Camii (Grand Mosque), dating back to the 18th century, collapsed, while the minaret of the Sarimiye Mosque, built in the 16th century, has toppled. Other historical buildings, including the governor's office, were also destroyed.

Kurdo recalled how people of different religions coexisted in the city. "We always lived together, we grew up together," he said. "We believe we will lift up Hatay again as one power."

Among the victims of the Feb. 6 earthquake were Saul Cenudioglu, leader of the Jewish community in Antakya, and his wife, Tuna Cenudioglu.

The Antioch Synagogue is still standing but there are cracks in the walls and debris everywhere, said Rabbi Mendy Chitrik, chairman of the Alliance of Rabbis in Islamic States.

‘Coexistence, tolerance’

Antakya has been home to Jews for more than 2,300 years but the community had shrunk to fewer than 20 in recent years.

"However small it was, it had a very big part in the heart of the city," Chitrik said. "The heart of Antakya always showed this coexistence, tolerance. It was quite amazing to see this real connection between different traditions, cultures, ethnic backgrounds."

Olcay Aydemir, an architect and restoration expert, said the region had experienced earthquakes over thousands of years and restoration efforts had to be sensitive.

"These structures rise from their ashes," she said. "These rocks should not be thrown away. The ones that can be re-used need to be re-used."

The structures that were still partly standing, such as the Habib-i Najjar Mosque, needed to be strengthened, Aydemir said, adding that every collapsed structure had to be examined individually to learn from the past and apply the lessons to the future.

"The last earthquake was bigger than expected. But it brought with it important data that could inform us about structures' weaknesses and reasons for their collapse," she said.



Scientists Produce Painstaking Wiring Diagram of a Mouse’s Brain

This image provided by the Allen Institute on April 8, 2025, shows a digital representation of neurons in a section of a mouse's brain, part of a project to create the largest map to date of brain wiring and function, in Seattle, Wash. (Forrest Collman/Allen Institute via AP)
This image provided by the Allen Institute on April 8, 2025, shows a digital representation of neurons in a section of a mouse's brain, part of a project to create the largest map to date of brain wiring and function, in Seattle, Wash. (Forrest Collman/Allen Institute via AP)
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Scientists Produce Painstaking Wiring Diagram of a Mouse’s Brain

This image provided by the Allen Institute on April 8, 2025, shows a digital representation of neurons in a section of a mouse's brain, part of a project to create the largest map to date of brain wiring and function, in Seattle, Wash. (Forrest Collman/Allen Institute via AP)
This image provided by the Allen Institute on April 8, 2025, shows a digital representation of neurons in a section of a mouse's brain, part of a project to create the largest map to date of brain wiring and function, in Seattle, Wash. (Forrest Collman/Allen Institute via AP)

Neuroscientists have produced the largest wiring diagram and functional map of a mammalian brain to date using tissue from a part of a mouse's cerebral cortex involved in vision, an achievement that could offer insight into how the human brain works.

They worked out the cerebral architecture in a tissue sample the size of a grain of sand bearing more than 200,000 cells including roughly 84,000 nerve cells, called neurons, and about 524 million connections between these neurons at junctions called synapses. In all, they collected data that covers about 3.4 miles (5.4 kilometers) of neuronal wiring in a part of the brain that processes visual information from the eyes.

"The millions of synapses and hundreds of thousands of cells come in such a diversity of shapes and sizes, and contain a massive complexity. Looking at their complexity gives, at least us, a sense of awe about the sheer complexity of our own minds," said neuroscientist Forrest Collman of the Allen Institute for Brain Science, one of the lead scientists in the research published on Wednesday in the journal Nature.

The cerebral cortex is the brain's outer layer, the main site of conscious perceptions, judgments and the planning and execution of movements.

"Scientists have been studying the structure and anatomy of the brain - including the morphology of different cell types and how they connect - for over a century. Simultaneously, they've been characterizing the function of neurons - for example, what information they process," said neuroscientist Andreas Tolias of Baylor College of Medicine, one of the research leaders.

"However, understanding how neuronal function emerges at the circuit level has been challenging, since we need to study both function and wiring in the same neurons. Our study represents the largest effort to date to systematically unify brain structure and function within a single individual mouse," Tolias added.

While there are notable differences between mouse and human brains, many organizational principles remain conserved across species.

The research focused upon a part of this region called the primary visual cortex, involved in the first stage of the brain's processing of visual information.

The research was conducted by the MICrONS, short for Machine Intelligence from Cortical Networks, a scientific consortium involving more than 150 scientists from various institutions.

Researchers at Baylor College of Medicine created a map of neural activity in a cubic millimeter of the primary visual cortex by recording brain cell responses while the laboratory mouse ran on a treadmill while watching a variety of video images, including from "The Matrix" films. The mouse had been genetically modified to make these cells emit a fluorescent substance when the neurons were active.

The same neurons were then imaged at the Allen Institute. Those images were assembled in three dimensions, and Princeton University researchers used artificial intelligence and machine learning to reconstruct the neurons and their connection patterns.

The brain is populated by a network of cells including neurons that are activated by sensory stimuli such as sight or sound or touch and are connected by synapses. Cognitive function involves the interplay between the activation of neurons and the connections among the brain cells.

The researchers see practical benefits from this type of research.

"First, understanding brain wiring rules can shed light on various neurological and psychiatric disorders, including autism and schizophrenia, which may arise from subtle wiring abnormalities. Second, knowing precisely how neuronal wiring shapes brain function allows us to uncover fundamental mechanisms of cognition," Tolias said.

One key finding highlighted in the research involved a map of how connections involving a broad class of neurons in the brain called inhibitory cells are organized. When these neurons become active, they make the cells to which they are connected less active. This stands in contrast to excitatory cells, which make the cells to which they connect more likely to become active. Inhibitory cells represent about 15% of the cortical neurons.

"We found many more highly specific patterns of inhibition than many, including us, were expecting to find," Collman said.

"Inhibitory cells don't just randomly connect to all the excitatory cells around them, but instead pick out very specific kinds of neurons to connect to. Further, it was known that there are four major kinds of inhibitory neurons in the cortex, but the patterns of specificity break up these categories into much finer groups," Collman said.