Stopping Aspirin Intake Raises Risks of Heart Attack

Doctors commonly prescribe daily low-dose aspirin after a heart attack to reduce the risk of having a second cardiovascular event. (Reuters)
Doctors commonly prescribe daily low-dose aspirin after a heart attack to reduce the risk of having a second cardiovascular event. (Reuters)
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Stopping Aspirin Intake Raises Risks of Heart Attack

Doctors commonly prescribe daily low-dose aspirin after a heart attack to reduce the risk of having a second cardiovascular event. (Reuters)
Doctors commonly prescribe daily low-dose aspirin after a heart attack to reduce the risk of having a second cardiovascular event. (Reuters)

Doctors commonly prescribe daily low-dose aspirin after a heart attack to reduce the risk of having a second cardiovascular event.

About one in six patients however stop taking their aspirin within three years, a Swedish study found. It warned against stopping the low dose of aspirin, because it raises the risk of heart attack or stroke by nearly 40 percent.

Lead author of the study Dr. Johan Sundstrom told Reuters Health that low-dose aspirin makes the platelets in the blood less likely to form clots. This is especially useful in the coronary or carotid arteries, where blood clots may lead to myocardial infarctions and strokes.

Sundstrom, an epidemiologist at Uppsala University added that millions of patients worldwide take aspirin on a daily basis and might consider stopping at some time during their life.

“We performed this study to help physicians and patients to make an informed decision whether or not to stop aspirin use,” he explained.

To see if risk rises after a patient stops aspirin therapy, Sundstrom’s team used nationwide medical and death registries to identify patients over age 40 taking low-dose aspirin. In Sweden, low-dose aspirin is available only by prescription, so the researchers were also able to see who continued filling their prescriptions between 2005 and 2009.

The researchers analyzed records for 601,527 patients, who were cancer-free and had taken at least 80 percent of their prescribed aspirin doses during the first year of treatment. After excluding a small proportion of patients whose medical records showed a reason for stopping aspirin, such as surgery or a case of severe bleeding, they found that about 15 percent of the full group had stopped taking their aspirin after about three years.

At the end of the study period, there were a total of 62,690 cardiovascular events, defined as hospitalization for a heart attack or stroke, or cardiovascular death.

The study lead author said patients who discontinued aspirin had a 37 percent higher rate of cardiovascular events than those who continued. That translates to one extra cardiovascular event each year among every 74 patients who stopped taking aspirin.

The risk increased shortly after discontinuation, and did not appear to diminish over time, he added.

“Adherence to low-dose aspirin treatment in the absence of major surgery or bleeding is likely an important treatment goal,” stressed Sundstrom.



Nepal Plans to Restrict Everest Permits to Experienced Climbers

FILE PHOTO: A mountaineer holds on to the rope during an ice climbing session at Everest base camp, Nepal April 15, 2025. REUTERS/Purnima Shrestha
FILE PHOTO: A mountaineer holds on to the rope during an ice climbing session at Everest base camp, Nepal April 15, 2025. REUTERS/Purnima Shrestha
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Nepal Plans to Restrict Everest Permits to Experienced Climbers

FILE PHOTO: A mountaineer holds on to the rope during an ice climbing session at Everest base camp, Nepal April 15, 2025. REUTERS/Purnima Shrestha
FILE PHOTO: A mountaineer holds on to the rope during an ice climbing session at Everest base camp, Nepal April 15, 2025. REUTERS/Purnima Shrestha

Nepal will issue Everest permits only to climbers with experience of scaling at least one of the Himalayan nation's 7,000-meter (22,965 ft) peaks, according to the draft of a new law aimed at reducing overcrowding and improving safety.
Nepal, which is heavily reliant on climbing, trekking and tourism for foreign exchange, has faced criticism for permitting too many climbers, including inexperienced ones, to try to ascend the 8,849-meter (29,032 ft) peak, Reuters reported.
This often results in long queues of climbers in the 'death Zone', an area below the summit with insufficient natural oxygen for survival.
Overcrowding has been blamed for the high number of deaths on the mountain. At least 12 climbers died, and another five went missing on Everest's slopes in 2023 when Nepal issued 478 permits. Eight climbers died last year.
Under the proposed law, an Everest permit would be issued only after a climber provides evidence of having climbed at least one 7,000-meter mountain in Nepal.
The sardar, or the head of local staff, and the mountain guide accompanying climbers must also be Nepali citizens.
The draft law has been registered at the National Assembly, the upper house of parliament, where the ruling alliance holds a majority required to pass the bill.
International expedition operators have urged Nepal to allow any 7,000-meter peak, not just those in the Himalayan nation, for the Everest permit.
"That wouldn't make any sense. And I would also add mountains that are close to 7,000 meters to that list and that are widely used as preparation, like Ama Dablam, Aconcagua, Denali and others," said Lukas Furtenbach of Austria-based expedition organizer, Furtenbach Adventures.
Furtenbach, currently leading an expedition on Everest, said mountain guides from other countries must also be allowed to work on Everest, as there are not enough qualified Nepali mountain guides.
"It is important that mountain guides have a qualification like IFMGA (International Federation of Mountain Guides Associations), no matter what nationality they are. We do also welcome Nepali IFMGA guides to work in the Alps in Europe," he told Reuters.
Garrett Madison of the US-based Madison Mountaineering also said a 6,500-meter peak anywhere in the world would be a better idea.
"It's too difficult to find a reasonable 7,000-meter plus peak in Nepal," Madison said.