Russian Scientists Revive Frog’s Heart after 45 Days of Freezing

A research scientist for the Washington Department of Fish and Wildlife pushes a Passive Integrated Transponder (PIT) tag under the skin of an Oregon spotted frog that will help in tracking the juvenile frog raised at the Woodland Park Zoo. AP file photo
A research scientist for the Washington Department of Fish and Wildlife pushes a Passive Integrated Transponder (PIT) tag under the skin of an Oregon spotted frog that will help in tracking the juvenile frog raised at the Woodland Park Zoo. AP file photo
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Russian Scientists Revive Frog’s Heart after 45 Days of Freezing

A research scientist for the Washington Department of Fish and Wildlife pushes a Passive Integrated Transponder (PIT) tag under the skin of an Oregon spotted frog that will help in tracking the juvenile frog raised at the Woodland Park Zoo. AP file photo
A research scientist for the Washington Department of Fish and Wildlife pushes a Passive Integrated Transponder (PIT) tag under the skin of an Oregon spotted frog that will help in tracking the juvenile frog raised at the Woodland Park Zoo. AP file photo

Russian scientists have managed to revive the heart of a frog after freezing it for 45 days as part of experiments aiming to prolong the period during which an organ is able to function normally and vitally.

This achievement is a significant development in the organ transplant field that would contribute in saving people’s lives.

Organ transplants such as kidneys and heart had long been a fictional idea. However, such transplants are currently practiced in hospitals in many countries.

But transplant scientists and surgeons now face a challenge in the ability of maintaining a specific organ functional after removing it from the donor. For instance, the period during which the heart muscle can be preserved before transferring it to the patient is not more than 6 hours, and this timeframe may not be sufficient for the transfer.

Studies indicate that doctors spoil about 60 percent of the organs that were preserved to be used later to treat patients, because of the time factor. Cells begin to lose capacity to carry out their vital functions, turning the organs useless.

The Russian Advanced Research Foundation has launched a scientific project aimed at developing a modern method to preserve human organs for an unlimited period of time without affecting their vital functions.

In the course of the experiments, scientists froze the heart of a frog and kept it at a temperature of -196 degrees Celsius for a month and a half, and then revived it. The post-revival tests showed that the heart was able to function vitally.

The head of the design team working on this project, Anatoly Kovtun, said that the success of these experiments would revolutionize the transfer of organs and transplant.

Finding a solution to the time challenge may help establish a "bank of frozen organs", which may save the lives of thousands of patients, he added in a press statement.



Tourists Return to Post-Olympic Paris for Holiday Magic

Around 270,000 people visited Notre Dame in the first eight days since its reopened. JULIEN DE ROSA / AFP
Around 270,000 people visited Notre Dame in the first eight days since its reopened. JULIEN DE ROSA / AFP
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Tourists Return to Post-Olympic Paris for Holiday Magic

Around 270,000 people visited Notre Dame in the first eight days since its reopened. JULIEN DE ROSA / AFP
Around 270,000 people visited Notre Dame in the first eight days since its reopened. JULIEN DE ROSA / AFP

Holidaymakers are returning to Paris for winter holiday magic as the tourism industry rebounds, inspired by the successful Olympic Games and the re-opening of Notre Dame cathedral.
"This year there is much more tourism than last time I came here. Much much more. Many more people," said Noemi Rizzato, a tourist from Milan who braved the cold to visit the Place du Trocadero on the Right Bank of Paris, bundled up in her down jacket, AFP said.
Georges Bardot, a 78-year-old pensioner from eastern France, also pointed to large numbers of foreign tourists amid the holiday hustle and bustle in the City of Light.
"We heard every language except French spoken on the metro," Bardot laughed.
This winter, Parisian hotels are experiencing a surge in demand.
The booking rate for two-week Christmas vacations neared 70 percent in mid-December, nine percentage points higher than a year ago, according to data from MKG Consulting.
Top-of-the-range establishments are doing particularly well, with an increase of nearly 14 points over one year.
According to the UMIH hotel and restaurant union, well-heeled international customers are making a comeback.
Frank Delvau, UMIH president for the Paris region, pointed to an "Olympic effect".
The Games "have made tourists want to come back, or to visit", he said.
Tourism professionals said the world's largest sporting event led to a lackluster summer in Paris.
Wealthy Parisians fled the capital for the summer and many foreign holidaymakers chose to stay away due to transport gridlock and a security crackdown. Hotels and airlines such as Air France saw a drop in bookings, while taxi drivers and restaurant owners said their businesses had been badly affected.
With five billion viewers, the Paris Games were the most followed Games in television and social media history, according to the International Olympic Committee.
- 'Time to go to Paris' -
"We needed this catch-up effect because the situation was very difficult in the third quarter," Delvau said.
"There was a very sharp fall in visitor numbers. The restaurant business was down 40 percent, 50 percent at times," he added.
From November 1 to December 8, international air arrivals to Paris rose by 15.4 percent compared to 2023, to reach 1.3 million, according to the Paris Tourist Office.
On the Ile de la Cite, the island site of Notre Dame cathedral, shopkeepers eagerly await the return of visitors after five years of reconstruction work, as well as the coronavirus lockdowns that saw a drop in tourist numbers.
"The Notre Dame opening this year was the biggest item on our list," said Teju Arora, an engineer from the United States.
"And we did visit Notre Dame, it was amazing. It's a beautiful site and it was great to see, to pray, to visit," said Arora, wearing a red beret.
Around 270,000 people have visited the medieval masterpiece in the first eight days since Notre Dame reopened in early December, rector Olivier Ribadeau Dumas told French daily Le Parisien. "Around 30,000 people a day enter the cathedral."
Tourists "tell themselves it's time to go to Paris", Delvau said.
"They have both Notre Dame and the department stores' windows, which always attract a lot of people."