Hiba Mustapha… An Egyptian Scientist Who Contributed to a Major US Experiment

Hiba Mustapha and Karen Carroll, the doctors who developed a test to diagnose the coronavirus (Johns Hopkins website)
Hiba Mustapha and Karen Carroll, the doctors who developed a test to diagnose the coronavirus (Johns Hopkins website)
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Hiba Mustapha… An Egyptian Scientist Who Contributed to a Major US Experiment

Hiba Mustapha and Karen Carroll, the doctors who developed a test to diagnose the coronavirus (Johns Hopkins website)
Hiba Mustapha and Karen Carroll, the doctors who developed a test to diagnose the coronavirus (Johns Hopkins website)

As scientists raced to confront the coronavirus, Johns Hopkins University’s name stood out as one of the most prominent sources of information on the pandemic’s spread, and the names of the scientists analyzing COVID-19 and studying its symptoms shined, as they developed one of the fastest and accurate tests to diagnose it.

Among those scientists is an Egyptian scientist who started working at Johns Hopkins University a few months ago and contributed to developing the diagnostic test that President Donald Trump considered to have “changed the rules of the game” of fighting the epidemic. Miss Mustapha and Karen Carroll, two epidemiologists at the university, developed the rapid test for detecting the coronavirus, providing a diagnosis within minutes.

Mustafa, an assistant professor of viral pathology at the Johns Hopkins University School of Medicine, spoke to Asharq Al-Awsat in an exclusive interview.

"When we started researching the novel virus, diagnostic tests were only available through the Centers for Disease Control and Prevention (CDC). It used to take a long time, as the tests had to be sent to the main laboratory or state laboratories. So we worked on developing a laboratory for analyzing samples and genetic material of the virus. We purchased the components from a pharmaceutical company and worked on developing the test until we were able to provide the test in mid-March”.

Mustapha considers that the virus spread across the world extensively and at an unexpected speed. Its symptoms resembled those of SARS, which broke out between 2002 and 2003 before research centers and universities managed to control its spread. COVID-19, on the other hand, is characterized by a more rapid spread and has infected many, especially those who have weak immune systems or other diseases that affect their respiratory system. This led some patients to need ventilators.

Dr. Mustafa emphasized that “social distancing is necessary and effective in reducing the spread of the virus and no hospital in the world is capable of providing enough ventilators for the massive number of victims at once”. She adds, “We did not expect this disease to become a pandemic, and so medical laboratories were unable to meet the increasing need for tests.

We worked for three days straight to develop a rapid test and conducted experiments in order to ensure its clinical accuracy. The test is based on a Polymerase Chain Reaction (PCR) that amplifies a small sample of genetic material obtained from the mouth or nose, and this allows the virologist to use specific computer software to determine whether the virus’s genetic material is present in the sample or not”.

The Egyptian scientist says: “On the first day we ran 50 samples, and in the following days our capacity expanded to 180 tests a day, then a thousand, and now we can run 1500 tests a day”.

Dr. Mustapha, who worked quietly alongside her colleagues to move the fight against the pandemic a step forward, comes from an Egyptian family and lived in Alexandria, where she graduated from the University of Alexandria’s Faculty of Medicine in 2004 and then went to the United States with her husband after obtaining a Ph.D. scholarship. She applied for her doctorate five years later, and then worked on "para flu" and influenza research at St. Jude Hospital, Tennessee

Later, Hiba Mustafa applied to a two-year scholarship at the University of Rochester in New York to study chemistry and microbiology and was among 12 scientists who were selected every year across the entire United States. This allowed her to earn a degree in Clinical Microbiology, and when Johns Hopkins University announced a vacancy at its Department of Microbiology, she applied for the job and was accepted in 2019.

Dr. Mustafa ruled out that the virus may evolve into a more dangerous and widespread virus while the death rate declines, but pointed out that eradicating it will not happen before reaching an effective vaccine, which is estimated to take at least one year.

She says: “The current research looks at the effect the virus has on the immune system, and the required medication to fight it, and at what part of the immune system needs to be boosted to fight the virus. We hope that the social distancing policy will continue until the rate of new cases declines and effective treatments and a vaccine are reached”.



Gemayel to Asharq Al-Awsat: Khaddam was Assad’s Stick to Apply Pressure

Relations between Gemayel and Khaddam were highly tense (Getty)
Relations between Gemayel and Khaddam were highly tense (Getty)
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Gemayel to Asharq Al-Awsat: Khaddam was Assad’s Stick to Apply Pressure

Relations between Gemayel and Khaddam were highly tense (Getty)
Relations between Gemayel and Khaddam were highly tense (Getty)

Late Syrian President Hafez al-Assad was a masterful negotiator, fiercely protective of his image and reputation. He was known for exhausting his guests with lengthy detours into history before addressing the substance of any talks.

Assad had an exceptional ability to restrain his anger, circling around an issue before striking again — often with calculated patience.

He avoided coarse language, allowing resentments to speak for themselves, but he never forgave those he believed had tried to derail his vision. Among them, according to accounts, were Yasser Arafat, Kamal Jumblatt, Bashir Gemayel, Amine Gemayel, and Samir Geagea.

In dealing with rivals and pressuring opponents, Assad often relied on a trusted enforcer: Abdel Halim Khaddam, his long-time foreign minister and later vice president. In the second part of his interview with Asharq Al-Awsat, former Lebanese President Amine Gemayel said Khaddam was Assad’s “stick,” used to assert control.

Many Lebanese politicians believed Khaddam’s bluntness was not personal, but rather a reflection of an official mandate from his mentor.

Assad rarely issued direct threats. Instead, he preferred subtle intimidation — as when he told Gemayel that his aides had once suggested blowing up President Anwar Sadat’s plane to prevent him from reaching Jerusalem.

Khaddam, the late Syrian strongman’s long-serving envoy, was known for humiliating both allies and foes who dared defy Damascus’ directives. His tactics were often unsettling — deliberately designed to leave visitors unnerved and pliant by the time they reached Assad’s office.

In a conversation in Paris during his retirement, Khaddam defended his hardline methods, saying they were not meant to insult but to prevent potentially dangerous confrontations. “The aim was to avoid escalation that could lead to security agencies taking over, which might have resulted in worse outcomes,” he said.

In the same meeting, Khaddam accused former Lebanese President Amine Gemayel of obstructing a political solution in Lebanon, calling him “hesitant and suspicious.”

He also acknowledged Assad was caught off guard when the Tripartite Agreement collapsed. The Syrian leader, Khaddam said, had not believed anyone in Lebanon would openly defy Syria — or the other Lebanese factions who had signed the accord.

“President Assad had many cards to play. President Sarkis had none,” recalled former Lebanese Foreign Minister Fouad Boutros, reflecting on the stark imbalance between Syria and Lebanon during Elias Sarkis’s presidency.

Assad, he said, had the power to topple or paralyze the Lebanese government before Sarkis even returned to Beirut. “Sarkis had no leverage over Assad,” Boutros noted. “But while Sarkis often showed flexibility, he would stand firm when asked to compromise Lebanon’s core principles.”

Boutros, who played a key role in Lebanon’s diplomacy during the civil war, said he had to exercise utmost restraint to keep Khaddam — Syria’s often abrasive envoy — from derailing talks with personal attacks or inflammatory language.

The dynamic, he suggested, was not unique to Sarkis. It also echoed the later, uneasy relationship between Gemayel and Assad.

Gemayel recalled a cold and confrontational relationship with Khaddam, describing him as “the stick and the poison” used by Assad to pressure Beirut into submission.

“There was no warmth between us from the beginning,” Gemayel told Asharq Al-Awsat.

“Khaddam used underhanded tactics to undermine the presidency and sow division within my team. While President Assad treated me with respect and politeness, he needed someone to apply pressure — and that was Khaddam,” he added.

Gemayel said Khaddam was behind all the pressure campaigns Syria waged against him — all with Assad’s full knowledge. “Assad played the courteous statesman. Khaddam handled the dirty work. Syria wanted me to sign agreements harmful to Lebanon’s interests, and Khaddam was the one tasked with forcing my hand.”

Despite Khaddam’s harsh demeanor, Gemayel said he never allowed him to overstep.

“I kept him in check. He didn’t dare cross the line with me. We were once in a meeting with President Assad, and Khaddam had been spreading ridiculous rumors beforehand. When he spoke up, I turned to Assad and said: ‘Mr. President, we have a problem with Khaddam. Please ask him to stop acting like a spy when dealing with us.’”

Khaddam, Gemayel said, tried to intimidate many Lebanese politicians — but not him.

“He was rude, even insolent to the point of absurdity. But he knew that if he said anything out of line with me, I would respond immediately.”

Assad’s Subtle Control and the Language of Minorities

Assad understood early on the fragility of Lebanon’s sectarian makeup. To him, the country was a meeting place for minorities — one that always needed an external patron to manage its wars and truces. He allowed for limited victories, but never total defeat, ensuring that no side could do without Syria’s oversight.

Assad sought to rule Syria indefinitely, with Lebanon as a backyard extension of his regime. Yet unlike his brother Rifaat, he avoided openly sectarian rhetoric or calls for partition. Rifaat, according to Gemayel, once suggested dividing both Syria and Lebanon along sectarian lines during a conversation with Lebanese leaders Walid Jumblatt and Marwan Hamadeh.

When asked whether he ever felt his dialogue with Assad was, at its core, a conversation between an Alawite and a Maronite, Gemayel replied: “No — that was Rifaat’s language. He used to say minorities must come together and show solidarity. But that narrative was never pushed by President Assad or his inner circle. It was always tailored to serve their own agenda.”

Assad’s political strategy was built on gathering leverage — and minority groups were central to that plan. His ties with Lebanon’s Druze community, and his clash with Druze leader Kamal Jumblatt, fit squarely within this framework. Assad relied on Syria’s own Druze population, as well as the Christian minority, to tighten his grip on the country’s diverse communities and align them under the banner of his regime.

“Assad had a firm hold on the minorities,” Gemayel said, adding that “he brought them all together to make them part of the Syrian system.”

Tensions between Syria’s Alawite leadership and the country’s Sunni majority were well known, Gemayel added, particularly through the candid rhetoric of Assad’s brother, Rifaat.

“Rifaat was open about the hostility between Alawites and Sunnis,” Gemayel said. “In his conversations with us, it was clear. But with President Assad, there was no visible sign of that. What lay beneath the surface, only God knows — but in our dealings with him, we never felt it.”

Gemayel Dismisses Reports of a Syria-Lebanon Confederation Proposal

Asked about longstanding claims that former Lebanese President Camille Chamoun had once proposed a confederation between Lebanon and Syria to Hafez al-Assad, Gemayel was quick to reject the idea.

“That’s absolutely not true,” he said. “President Chamoun would never have made such a proposal. A lot of things were said at the time. There were even reports that US envoy Dean Brown had suggested relocating Lebanon’s Christians to California — all of it nonsense, poetic talk with no grounding in reality.”

Gemayel also addressed one of the most controversial moments in US diplomacy during Lebanon’s 1988 presidential crisis: the phrase reportedly used by US envoy Richard Murphy — “Mikhael Daher or chaos.”

Daher, a Christian MP close to Damascus, had been floated as the only candidate acceptable to both Syria and the United States.

But Washington later distanced itself from the deal. The episode, Gemayel said, underscored a period in which American pressure aligned more with Syrian — and by extension, Israeli — interests, leaving Lebanon’s sovereignty hanging in the balance.

Gemayel confirmed that US envoy Richard Murphy did indeed issue the stark ultimatum in 1988. The phrase, which became emblematic of foreign interference in Lebanon’s presidential crisis, reflected what Gemayel described as Washington’s unwillingness to confront Damascus — despite acknowledging its destabilizing role in Lebanon.

“Yes, Murphy said it,” Gemayel affirmed to Asharq Al-Awsat.

“The Americans had a problem — they wanted Syria, and they didn’t. They knew Syria was playing a destructive role in Lebanon, but they didn’t want to challenge it. They kept trying to find common ground with Syria, not with us.”

According to Gemayel, the US saw Daher — a respected Christian parliamentarian close to Damascus — as a palatable compromise. “They thought Daher was a respectable figure who might be acceptable to the Lebanese, so they went along with Syria’s choice,” he said.

Washington, he added, had consistently prioritized pragmatism over principle in Lebanon, often aligning with whichever side could deliver results — even if it came at Beirut’s expense.

“It was the same with the May 17 Agreement with Israel,” Gemayel said, referring to the short-lived 1983 accord.

“The US couldn't pressure Israel, so Lebanon had to pay. And they couldn’t pressure Syria either — Syria was stubborn, had resources, and they didn’t want a confrontation. So they kept trying to sell us solutions that weren’t in Lebanon’s interest.”

“The Americans were always looking for the quickest deal,” he added. “They wanted to please both Syria and Israel. With Syria, it was clear — they didn’t want to upset Assad, because they knew who held the real power in Lebanon.”

Gemayel said that while he personally held the reins in decision-making and negotiations with Syria during his time in office, several close advisers and intermediaries played essential roles in laying the groundwork for dialogue with Damascus.

“The relationship and final decisions were in my hands,” he told Asharq Al-Awsat.

“I was the one doing the actual negotiating. But when it came to preparation, the late Jean Obeid played a very valuable role. He was intelligent, committed to Lebanon’s interests, and had close ties with the Syrians. He couldn’t get everything done, but he managed to ease certain issues,” said Gemayel.

Gemayel also credited Eli Salem, another aide, for navigating delicate talks with Syrian officials — particularly with Khaddam.

“Salem had a knack for getting through on specific points,” Gemayel said. “He had good chemistry with Khaddam, and that helped, especially since Khaddam and I didn’t get along.”

One figure who unexpectedly played a constructive role, according to Gemayel, was Brigadier General Jamil al-Sayyed, then an intelligence officer stationed in Lebanon’s eastern Bekaa Valley.

“You may be surprised,” he said, “but Jamil al-Sayyed was very helpful. Whenever I was heading to Damascus, I would stop in the Bekaa to meet him. He gave me very precise insights into what was happening at the Syrian presidential palace and the broader picture in Damascus. He was well-informed, sincere, and provided intelligence that wasn’t widely available — information that truly benefited Lebanon.”

Asked whether Syria was uneasy about the role of veteran journalist and diplomat Ghassan Tueni in his administration, Gemayel said the Syrians had little affection for him.

“There was never any warmth toward Ghassan,” he said. “He came with me to Syria just once, and it was clear there was tension. Whenever he was present, things got heated. Ghassan and Khaddam were like a ping-pong match — constantly hitting the ball back and forth.”

The friction, Gemayel explained, stemmed in large part from Tueni’s association with An-Nahar, the Beirut daily he helped lead, which often published sharp criticism of Syria.

“Syria never appreciated An-Nahar,” Gemayel said. “Even if Ghassan tried to distance himself from specific articles, the content was out there for everyone to see — and the Syrians didn’t forget it.”