Hiba Mustapha… An Egyptian Scientist Who Contributed to a Major US Experiment

Hiba Mustapha and Karen Carroll, the doctors who developed a test to diagnose the coronavirus (Johns Hopkins website)
Hiba Mustapha and Karen Carroll, the doctors who developed a test to diagnose the coronavirus (Johns Hopkins website)
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Hiba Mustapha… An Egyptian Scientist Who Contributed to a Major US Experiment

Hiba Mustapha and Karen Carroll, the doctors who developed a test to diagnose the coronavirus (Johns Hopkins website)
Hiba Mustapha and Karen Carroll, the doctors who developed a test to diagnose the coronavirus (Johns Hopkins website)

As scientists raced to confront the coronavirus, Johns Hopkins University’s name stood out as one of the most prominent sources of information on the pandemic’s spread, and the names of the scientists analyzing COVID-19 and studying its symptoms shined, as they developed one of the fastest and accurate tests to diagnose it.

Among those scientists is an Egyptian scientist who started working at Johns Hopkins University a few months ago and contributed to developing the diagnostic test that President Donald Trump considered to have “changed the rules of the game” of fighting the epidemic. Miss Mustapha and Karen Carroll, two epidemiologists at the university, developed the rapid test for detecting the coronavirus, providing a diagnosis within minutes.

Mustafa, an assistant professor of viral pathology at the Johns Hopkins University School of Medicine, spoke to Asharq Al-Awsat in an exclusive interview.

"When we started researching the novel virus, diagnostic tests were only available through the Centers for Disease Control and Prevention (CDC). It used to take a long time, as the tests had to be sent to the main laboratory or state laboratories. So we worked on developing a laboratory for analyzing samples and genetic material of the virus. We purchased the components from a pharmaceutical company and worked on developing the test until we were able to provide the test in mid-March”.

Mustapha considers that the virus spread across the world extensively and at an unexpected speed. Its symptoms resembled those of SARS, which broke out between 2002 and 2003 before research centers and universities managed to control its spread. COVID-19, on the other hand, is characterized by a more rapid spread and has infected many, especially those who have weak immune systems or other diseases that affect their respiratory system. This led some patients to need ventilators.

Dr. Mustafa emphasized that “social distancing is necessary and effective in reducing the spread of the virus and no hospital in the world is capable of providing enough ventilators for the massive number of victims at once”. She adds, “We did not expect this disease to become a pandemic, and so medical laboratories were unable to meet the increasing need for tests.

We worked for three days straight to develop a rapid test and conducted experiments in order to ensure its clinical accuracy. The test is based on a Polymerase Chain Reaction (PCR) that amplifies a small sample of genetic material obtained from the mouth or nose, and this allows the virologist to use specific computer software to determine whether the virus’s genetic material is present in the sample or not”.

The Egyptian scientist says: “On the first day we ran 50 samples, and in the following days our capacity expanded to 180 tests a day, then a thousand, and now we can run 1500 tests a day”.

Dr. Mustapha, who worked quietly alongside her colleagues to move the fight against the pandemic a step forward, comes from an Egyptian family and lived in Alexandria, where she graduated from the University of Alexandria’s Faculty of Medicine in 2004 and then went to the United States with her husband after obtaining a Ph.D. scholarship. She applied for her doctorate five years later, and then worked on "para flu" and influenza research at St. Jude Hospital, Tennessee

Later, Hiba Mustafa applied to a two-year scholarship at the University of Rochester in New York to study chemistry and microbiology and was among 12 scientists who were selected every year across the entire United States. This allowed her to earn a degree in Clinical Microbiology, and when Johns Hopkins University announced a vacancy at its Department of Microbiology, she applied for the job and was accepted in 2019.

Dr. Mustafa ruled out that the virus may evolve into a more dangerous and widespread virus while the death rate declines, but pointed out that eradicating it will not happen before reaching an effective vaccine, which is estimated to take at least one year.

She says: “The current research looks at the effect the virus has on the immune system, and the required medication to fight it, and at what part of the immune system needs to be boosted to fight the virus. We hope that the social distancing policy will continue until the rate of new cases declines and effective treatments and a vaccine are reached”.



Fear Stalks Tehran as Israel Bombards, Shelters Fill Up and Communicating Grows Harder

Shops remain shuttered Tehran's historic Grand Bazaar, Monday, June 16, 2025. (AP)
Shops remain shuttered Tehran's historic Grand Bazaar, Monday, June 16, 2025. (AP)
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Fear Stalks Tehran as Israel Bombards, Shelters Fill Up and Communicating Grows Harder

Shops remain shuttered Tehran's historic Grand Bazaar, Monday, June 16, 2025. (AP)
Shops remain shuttered Tehran's historic Grand Bazaar, Monday, June 16, 2025. (AP)

The streets of Tehran are empty, businesses closed, communications patchy at best. With no bona fide bomb shelters open to the public, panicked masses spend restless nights on the floors of metro stations as strikes boom overhead.

This is Iran’s capital city, just under a week into a fierce Israeli blitz to destroy the country's nuclear program and its military capabilities. After knocking out much of Iran's air defense system, Israel says its warplanes have free rein over the city's skies. US President Donald Trump on Monday told Tehran's roughly 10 million residents to evacuate “immediately.”

Thousands have fled, spending hours in gridlock as they head toward the suburbs, the Caspian Sea, or even Armenia or Türkiye. But others — those elderly and infirm — are stuck in high-rise apartment buildings. Their relatives fret: what to do?

Israeli strikes on Iran have killed at least 585 people and wounded over 1,300, a human rights group says. State media, also a target of bombardment, have stopped reporting on the attacks, leaving Iranians in the dark. There are few visible signs of state authority: Police appear largely undercover, air raid sirens are unreliable, and there’s scant information on what to do in case of attack.

Shirin, 49, who lives in the southern part of Tehran, said every call or text to friends and family in recent days has felt like it could be the last.

“We don’t know if tomorrow we will be alive,” she said.

Many Iranians feel conflicted. Some support Israel's targeting of Iranian political and military officials they see as repressive. Others staunchly defend the country and retaliatory strikes on Israel. Then, there are those who oppose Iran’s rulers, but still don't want to see their country bombed.

To stay, or to go? The Associated Press interviewed five people in Iran and one Iranian American in the US over the phone. All spoke either on the condition of anonymity or only allowed their first names to be used, for fear of retribution from the state against them or their families.

Most of the calls ended abruptly and within minutes, cutting off conversations as people grew nervous or because the connection dropped. Iran’s government has acknowledged disrupting internet access. It says it's to protect the country, though that has blocked average Iranians from getting information from the outside world.

Iranians in the diaspora wait anxiously for news from relatives. One, an Iranian American human rights researcher in the US, said he last heard from relatives when some were trying to flee Tehran earlier in the week. He believes that lack of gas and traffic prevented them from leaving.

The most heartbreaking interaction, he said, was when his older cousins with whom he grew up in Iran told him “We don’t know where to go. If we die, we die.”

“Their sense was just despair,” he said.

Some families have made the decision to split up.

A 23-year-old Afghan refugee who has lived in Iran for four years said he stayed behind in Tehran but sent his wife and newborn son out of the city after a strike Monday hit a nearby pharmacy.

“It was a very bad shock for them,” he said.

Some, like Shirin, said fleeing was not an option. The apartment buildings in Tehran are towering and dense. Her father has Alzheimer’s and needs an ambulance to move. Her mother's severe arthritis would make even a short trip extremely painful.

Still, hoping escape might be possible, she spent the last several days trying to gather their medications. Her brother waited at a gas station until 3 a.m., only to be turned away when the fuel ran out. As of Monday, gas was being rationed to under 20 liters (5 gallons) per driver at stations across Iran after an Israeli strike set fire to the world's largest gas field.

Some people, like Arshia, said they are just tired.

“I don’t want to go in traffic for 40 hours, 30 hours, 20 hours, just to get to somewhere that might get bombed eventually,” he said.

The 22-year-old has been staying in the house with his parents since the initial Israeli strike. He said his once-lively neighborhood of Saadat Abad in northwestern Tehran is now a ghost town. Schools are closed. Very few people even step outside to walk their dogs. Most local stores have run out of drinking water and cooking oil. Others closed.

Still, Arshia said the prospect of finding a new place is too daunting.

“We don’t have the resources to leave at the moment,” he said.

Residents are on their own

No air raid sirens went off as Israeli strikes began pounding Tehran before dawn Friday. For many, it was an early sign civilians would have to go it alone.

During the Iran-Iraq war in the 1980s, Tehran was a low-slung city, many homes had basements to shelter in, and there were air raid drills and sirens. Now the capital is packed with close-built high-rise apartments without shelters.

“It's a kind of failing of the past that they didn’t build shelters,” said a 29-year-old Tehran resident who left the city Monday. “Even though we’ve been under the shadow of a war, as long as I can remember.”

Her friend's boyfriend was killed while going to the store.

“You don’t really expect your boyfriend or your anyone, really to leave the house and never return when they just went out for a routine normal shopping trip,” she said.

Those who choose to relocate do so without help from the government. The state has said it is opening mosques, schools and metro stations for use as shelters. Some are closed, others overcrowded.

Hundreds crammed into one Tehran metro station Friday night. Small family groups lay on the floor. One student, a refugee from another country, said she spent 12 hours in the station with her relatives.

“Everyone there was panicking because of the situation,” she said. “Everyone doesn’t know what will happen next, if there is war in the future and what they should do. People think nowhere is safe for them.”

Soon after leaving the station, she saw that Israel had warned a swath of Tehran to evacuate.

“For immigrant communities, this is so hard to live in this kind of situation,” she said, explaining she feels like she has nowhere to escape to, especially not her home country, which she asked not be identified.

Fear of Iran mingles with fear of Israel

For Shirin, the hostilities are bittersweet. Despite being against the theocracy and its treatment of women, the idea that Israel may determine the future does not sit well with her.

“As much as we want the end of this regime, we didn’t want it to come at the hands of a foreign government,” she said. “We would have preferred that if there were to be a change, it would be the result of a people’s movement in Iran.”

Meanwhile, the 29-year-old who left Tehran had an even more basic message for those outside Iran:

“I just want people to remember that whatever is happening here, it’s not routine business for us. People’s lives here — people’s livelihoods — feel as important to them as they feel to anyone in any other place. How would you feel if your city or your country was under bombardment by another country, and people were dying left and right?”

“We are kind of like, this can’t be happening. This can’t be my life.”