Hiba Mustapha… An Egyptian Scientist Who Contributed to a Major US Experiment

Hiba Mustapha and Karen Carroll, the doctors who developed a test to diagnose the coronavirus (Johns Hopkins website)
Hiba Mustapha and Karen Carroll, the doctors who developed a test to diagnose the coronavirus (Johns Hopkins website)
TT
20

Hiba Mustapha… An Egyptian Scientist Who Contributed to a Major US Experiment

Hiba Mustapha and Karen Carroll, the doctors who developed a test to diagnose the coronavirus (Johns Hopkins website)
Hiba Mustapha and Karen Carroll, the doctors who developed a test to diagnose the coronavirus (Johns Hopkins website)

As scientists raced to confront the coronavirus, Johns Hopkins University’s name stood out as one of the most prominent sources of information on the pandemic’s spread, and the names of the scientists analyzing COVID-19 and studying its symptoms shined, as they developed one of the fastest and accurate tests to diagnose it.

Among those scientists is an Egyptian scientist who started working at Johns Hopkins University a few months ago and contributed to developing the diagnostic test that President Donald Trump considered to have “changed the rules of the game” of fighting the epidemic. Miss Mustapha and Karen Carroll, two epidemiologists at the university, developed the rapid test for detecting the coronavirus, providing a diagnosis within minutes.

Mustafa, an assistant professor of viral pathology at the Johns Hopkins University School of Medicine, spoke to Asharq Al-Awsat in an exclusive interview.

"When we started researching the novel virus, diagnostic tests were only available through the Centers for Disease Control and Prevention (CDC). It used to take a long time, as the tests had to be sent to the main laboratory or state laboratories. So we worked on developing a laboratory for analyzing samples and genetic material of the virus. We purchased the components from a pharmaceutical company and worked on developing the test until we were able to provide the test in mid-March”.

Mustapha considers that the virus spread across the world extensively and at an unexpected speed. Its symptoms resembled those of SARS, which broke out between 2002 and 2003 before research centers and universities managed to control its spread. COVID-19, on the other hand, is characterized by a more rapid spread and has infected many, especially those who have weak immune systems or other diseases that affect their respiratory system. This led some patients to need ventilators.

Dr. Mustafa emphasized that “social distancing is necessary and effective in reducing the spread of the virus and no hospital in the world is capable of providing enough ventilators for the massive number of victims at once”. She adds, “We did not expect this disease to become a pandemic, and so medical laboratories were unable to meet the increasing need for tests.

We worked for three days straight to develop a rapid test and conducted experiments in order to ensure its clinical accuracy. The test is based on a Polymerase Chain Reaction (PCR) that amplifies a small sample of genetic material obtained from the mouth or nose, and this allows the virologist to use specific computer software to determine whether the virus’s genetic material is present in the sample or not”.

The Egyptian scientist says: “On the first day we ran 50 samples, and in the following days our capacity expanded to 180 tests a day, then a thousand, and now we can run 1500 tests a day”.

Dr. Mustapha, who worked quietly alongside her colleagues to move the fight against the pandemic a step forward, comes from an Egyptian family and lived in Alexandria, where she graduated from the University of Alexandria’s Faculty of Medicine in 2004 and then went to the United States with her husband after obtaining a Ph.D. scholarship. She applied for her doctorate five years later, and then worked on "para flu" and influenza research at St. Jude Hospital, Tennessee

Later, Hiba Mustafa applied to a two-year scholarship at the University of Rochester in New York to study chemistry and microbiology and was among 12 scientists who were selected every year across the entire United States. This allowed her to earn a degree in Clinical Microbiology, and when Johns Hopkins University announced a vacancy at its Department of Microbiology, she applied for the job and was accepted in 2019.

Dr. Mustafa ruled out that the virus may evolve into a more dangerous and widespread virus while the death rate declines, but pointed out that eradicating it will not happen before reaching an effective vaccine, which is estimated to take at least one year.

She says: “The current research looks at the effect the virus has on the immune system, and the required medication to fight it, and at what part of the immune system needs to be boosted to fight the virus. We hope that the social distancing policy will continue until the rate of new cases declines and effective treatments and a vaccine are reached”.



Israel Wary of Egypt's 'Military Infrastructure' in Sinai: Peace Treaty at Risk?

Egyptian army chief Ahmed Khalifa inspects troops near Israel's border late last year. (Military spokesman)
Egyptian army chief Ahmed Khalifa inspects troops near Israel's border late last year. (Military spokesman)
TT
20

Israel Wary of Egypt's 'Military Infrastructure' in Sinai: Peace Treaty at Risk?

Egyptian army chief Ahmed Khalifa inspects troops near Israel's border late last year. (Military spokesman)
Egyptian army chief Ahmed Khalifa inspects troops near Israel's border late last year. (Military spokesman)

Israel has voiced growing concerns over Egypt’s military presence in the Sinai Peninsula, fearing a potential escalation between the two sides amid the ongoing Gaza war.

Israeli media reports said Prime Minister Benjamin Netanyahu’s government has asked both Washington and Cairo to dismantle what it describes as a “military infrastructure” established by the Egyptian army in Sinai.

However, an informed Egyptian source and experts cited by Asharq Al-Awsat insisted that Egypt has not violated its peace treaty with Israel. They argued that Cairo’s military movements are a response to Israeli breaches of the agreement.

Israel’s Israel Hayom newspaper, citing a senior Israeli security official, reported that Egypt’s military buildup in Sinai constitutes a “major violation” of the security annex of the peace treaty.

The official said the issue is a top priority for Israeli Defense Minister Israel Katz, stressing that Israel “will not accept this situation” amid what it views as Egypt’s growing military footprint in the peninsula.

The official added that the issue goes beyond the deployment of Egyptian forces in Sinai exceeding the quotas set under the military annex of the Camp David Accords.

The real concern, he said, lies in Egypt’s continued military buildup in the peninsula, which Israel views as an irreversible step.

Moreover, he stressed that while Israel is not seeking to amend its peace treaty with Egypt or redeploy troops along the border, it believes the current situation requires urgent action to prevent a potential escalation.

Egypt-Israel relations have not seen such tensions since the outbreak of the Gaza war, particularly after Israel violated a ceasefire agreement with Hamas brokered primarily by Egypt. Israeli forces resumed airstrikes on Gaza last month and failed to fulfill their commitments to withdraw from the Philadelphi Corridor and Palestinian border crossings.

A senior Egyptian source dismissed Israel’s accusations, telling Asharq Al-Awsat that “these repeated Israeli pretexts ignore the fact that Israeli forces have violated the peace treaty, seizing control of areas where Egypt objects to their presence without the necessary coordination with Cairo.”

Egypt has the right to take all necessary measures to safeguard its national security against any threats, emphasized the source.

“Nevertheless, Cairo remains fully committed to the peace treaty and has no intention of aggression against any party,” it added.

Israeli forces seized control of the Gaza-Egypt border, including the Philadelphi Corridor and the Rafah crossing, in May 2024. Israel has accused Egypt of not doing enough to stop weapons smuggling into Gaza through border tunnels—an allegation Cairo has denied.

Under the terms of the ceasefire agreement with Hamas, which Israel later broke, Israeli forces were supposed to begin withdrawing from the Philadelphi Corridor on March 1, completing the pullout within eight days. However, Israel failed to do so and instead resumed airstrikes on Gaza.

Israel also announced the creation of an administration aimed at facilitating the “voluntary departure” of Gaza residents, a move Cairo strongly rejected and formally condemned.

Egypt has insisted that Palestinians must remain in their homeland and has put forward a reconstruction plan for Gaza and called for the implementation of the two-state solution. The plan was endorsed at an emergency Arab summit three weeks ago.

Media reports have indicated that Egypt responded to Israel’s control of the Gaza border by increasing its military presence near the frontier—an act that some Israeli officials claim violates the peace treaty and threatens Israel’s security.

Former Egyptian intelligence official Gen. Mohammed Rashad told Asharq Al-Awsat that Israel itself violated the peace treaty by seizing the Philadelphi Corridor, controlling border crossings, and blocking aid to Gaza while seeking to forcibly displace Palestinians into Egypt.

“Every Israeli action along Gaza’s border with Egypt constitutes hostile behavior against Egypt’s national security,” said Rashad, who previously headed the Israeli military affairs division in Egypt’s intelligence service.

“Egypt cannot sit idly by in the face of such threats and must prepare for all possible scenarios.”

The Philadelphi Corridor is a strategically sensitive buffer zone, serving as a narrow 14-kilometer passage between Egypt, Israel, and Gaza, stretching from the Mediterranean Sea in the north to the Kerem Shalom crossing in the south.

Military expert General Samir Farag insisted that Egypt has not violated the peace treaty or its security annex in over 40 years, arguing that Israel has repeatedly breached the agreement and is attempting to shift blame onto Cairo.

“Israel is doing this to distract from its internal problems, including public discontent over its ballooning defense budget,” Farag told Asharq Al-Awsat.

“It also wants to deflect attention from Egypt’s reconstruction plan for Gaza and leverage its claims to pressure the United States for more military aid by portraying Egypt as a threat.”

Farag emphasized that Egypt’s actions are solely aimed at protecting its national security, adding: “There is no clause in the peace treaty that prevents a country from defending itself.”

“The so-called ‘military infrastructure’ Israel refers to consists of roads and development projects in Sinai.”

“The US has satellite surveillance over the region—if Egypt had violated the treaty, Washington would have flagged it. Moreover, security coordination between Egypt and Israel continues daily,” he explained.

Egypt and Israel signed their landmark peace treaty on March 25, 1979, committing to resolving disputes peacefully and prohibiting the use or threat of force. The agreement also established military deployment guidelines and a joint security coordination committee.

Meanwhile, US Republican Party member Tom Harb told Asharq Al-Awsat that Washington has received intelligence from multiple sources indicating that Egypt has amassed a significant military force in Sinai.

Israel considers this a breach of the peace treaty, which designates Sinai as a demilitarized zone to prevent surprises like the 1973 war, Harb said.

While the US fully supports Israel’s concerns, it also wants to prevent further escalation, as that would destabilize the region, he added.

Ultimately, Egypt must clarify whether its troop movements are aimed at threatening Israel or preventing Palestinians from crossing into Egyptian territory, he stated.