Scientists Develop Electrically Charged Patch for Faster Wound Healing

A child shows her adhesive bandage after being inoculated with Pfizer-BioNTech vaccine against the coronavirus disease (COVID-19), during the vaccine rollout for children with comorbidities, in Pasig, Metro Manila, Philippines, October 15, 2021. REUTERS/Lisa Marie David
A child shows her adhesive bandage after being inoculated with Pfizer-BioNTech vaccine against the coronavirus disease (COVID-19), during the vaccine rollout for children with comorbidities, in Pasig, Metro Manila, Philippines, October 15, 2021. REUTERS/Lisa Marie David
TT

Scientists Develop Electrically Charged Patch for Faster Wound Healing

A child shows her adhesive bandage after being inoculated with Pfizer-BioNTech vaccine against the coronavirus disease (COVID-19), during the vaccine rollout for children with comorbidities, in Pasig, Metro Manila, Philippines, October 15, 2021. REUTERS/Lisa Marie David
A child shows her adhesive bandage after being inoculated with Pfizer-BioNTech vaccine against the coronavirus disease (COVID-19), during the vaccine rollout for children with comorbidities, in Pasig, Metro Manila, Philippines, October 15, 2021. REUTERS/Lisa Marie David

A team of researchers working at the University of Electronic Science and Technology of China has developed an electrically charged thin film patch for promoting faster wound healing.

In their paper published in the Science Advances journal, the group describes their patch, how it works, and how well it performed when tested on rats.

For thousands of years, humans have been looking for ways to promote faster healing of wounds in order to reduce both the length of time a patient experiences pain and the chances of infection. In this new effort, the researchers created an electrically charged thin film patch that helps wounds heal faster.

Prior research has shown that applying electricity to wounds induces faster healing. Unfortunately, this approach has been limited by bulky and complicated machinery. In this new effort, the researchers created a small, flexible patch that takes advantage of electricity's healing powers without the need for such equipment.

The patch is four-layered: the top and bottom layers are made of a type of electrically charged plastic and they get their charge through contact with the skin. One of the middle layers is made of a silicone rubber gel that helps the patch conform to the contours of the skin. The other middle layer is made of a shape-memory alloy material; its purpose is to pull the sides of the wound closer. The resulting thin-film patch is just 0.2 millimeters thick.

The researchers applied the patch to two kinds of wounds on test rats—straight and circular. They compared healing rates against other types of dressings and against undressed wounds.

They found that circular wounds treated with the patch were 96.8 percent healed after eight days, compared to 76.4 to 79.9 percent for other dressings. Those that went untreated were only 45.9 percent healed.

They found similar results in straight-line wound healing, though all of them healed faster than the circular wounds—such wounds require far less new skin development to heal.

The researchers suggest their patch is a viable wound treatment option and plan to continue upgrading its features, such as allowing for differently shaped wounds.



Rwanda and WHO Declare End of Marburg Outbreak after No New Cases Reported

In this Oct. 8, 2014 photo, a medical worker from the Infection Prevention and Control unit wearing full protective equipment carries a meal to an isolation tent housing a man being quarantined after coming into contact in Uganda with a carrier of the Marburg Virus, at the Kenyatta National Hospital in Nairobi, Kenya. (AP)
In this Oct. 8, 2014 photo, a medical worker from the Infection Prevention and Control unit wearing full protective equipment carries a meal to an isolation tent housing a man being quarantined after coming into contact in Uganda with a carrier of the Marburg Virus, at the Kenyatta National Hospital in Nairobi, Kenya. (AP)
TT

Rwanda and WHO Declare End of Marburg Outbreak after No New Cases Reported

In this Oct. 8, 2014 photo, a medical worker from the Infection Prevention and Control unit wearing full protective equipment carries a meal to an isolation tent housing a man being quarantined after coming into contact in Uganda with a carrier of the Marburg Virus, at the Kenyatta National Hospital in Nairobi, Kenya. (AP)
In this Oct. 8, 2014 photo, a medical worker from the Infection Prevention and Control unit wearing full protective equipment carries a meal to an isolation tent housing a man being quarantined after coming into contact in Uganda with a carrier of the Marburg Virus, at the Kenyatta National Hospital in Nairobi, Kenya. (AP)

The World Health Organization and the Rwandan government on Friday declared the outbreak in Rwanda of the Ebola-like Marburg fever over after no new cases were registered in recent weeks.

The country first declared the outbreak on Sept. 27 and reported a total of 15 deaths and 66 cases, with the majority of those affected healthcare workers who handled the first patients.

Without treatment, Marburg can be fatal in up to 88% of people who fall ill with the disease. Symptoms include fever, muscle pains, diarrhea, vomiting and, in some cases, death through extreme blood loss.

There is no authorized vaccine or treatment for Marburg, though Rwanda received hundreds of doses of a vaccine under trial in October.

An outbreak is considered over after 42 days — two 21-day incubation cycles of the virus — elapsed without registering new cases and all existing cases test negative.

Rwanda discharged the last Marburg patient on Nov. 8 and had reported no new confirmed cases since Oct. 30.

However, WHO officials and Rwanda's Health Minister Dr. Sabin Nzanzimana on Friday said risks remain and that people should stay vigilant.

“We believe it’s not completely over because we still face risks, especially from bats. We are continuing to build new strategies, form new health teams, and deploy advanced technologies to track their movements, understand their behavior, and monitor who is interacting with them,” the minister announced during a press conference in the capital, Kigali.

Like Ebola, the Marburg virus is believed to originate in fruit bats and spreads between people through close contact with the bodily fluids of infected individuals or with surfaces, such as contaminated bed sheets.

“I thank the government of Rwanda, its leadership and Rwandans in general for the strong response to achieve this success but the battle continues,” said the WHO representative in Rwanda, Dr. Brain Chirombo.

Marburg outbreaks and individual cases have in the past been recorded in Tanzania, Equatorial Guinea, Angola, Congo, Kenya, South Africa, Uganda and Ghana.

The virus was first identified in 1967 after it caused simultaneous outbreaks of disease in laboratories in the German city of Marburg and in Belgrade in the former Yugoslavia. Seven people died after being exposed to the virus while conducting research on monkeys.