Mushers and Dogs Braved Horrific Alaska Winter to Deliver Lifesaving Serum 100 Years Ago

FILE - The snow-covered coastal plain area of the Arctic National Wildlife Refuge is seen, with the Brooks Range at right, Monday, Oct. 14, 2024, near Kaktovik, Alaska. (AP Photo/Lindsey Wasson)
FILE - The snow-covered coastal plain area of the Arctic National Wildlife Refuge is seen, with the Brooks Range at right, Monday, Oct. 14, 2024, near Kaktovik, Alaska. (AP Photo/Lindsey Wasson)
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Mushers and Dogs Braved Horrific Alaska Winter to Deliver Lifesaving Serum 100 Years Ago

FILE - The snow-covered coastal plain area of the Arctic National Wildlife Refuge is seen, with the Brooks Range at right, Monday, Oct. 14, 2024, near Kaktovik, Alaska. (AP Photo/Lindsey Wasson)
FILE - The snow-covered coastal plain area of the Arctic National Wildlife Refuge is seen, with the Brooks Range at right, Monday, Oct. 14, 2024, near Kaktovik, Alaska. (AP Photo/Lindsey Wasson)

The Alaska Gold Rush town of Nome faced a bleak winter. It was hundreds of miles from anywhere, cut off by the frozen sea and unrelenting blizzards, and under siege from a contagious disease known as the “strangling angel” for the way it suffocated children.
Now, 100 years later, Nome is remembering its saviors — the sled dogs and mushers who raced for more than five days through hypothermia, frostbite, gale-force winds and blinding whiteouts to deliver life-saving serum and free the community from the grip of diphtheria, The Associated Press reported.
Among the events celebrating the centennial of the 1925 “Great Race of Mercy” are lectures, a dog-food drive and a reenactment of the final leg of the relay, all organized by the Nome Kennel Club.
Remembering the mushers and dogs for ‘heroic effort’ “There’s a lot of fluff around celebrations like this, but we wanted to remember the mushers and their dogs who have been at the center of this heroic effort and ... spotlight mushing as a still-viable thing for the state of Alaska,” said Diana Haecker, a kennel club board member and co-owner of Alaska’s oldest newspaper, the Nome Nugget.
“People just dropped whatever they were doing," she said. "These mushers got their teams ready and went, even though it was really cold and challenging conditions on the trail.”
Other communities are also marking the anniversary — including the village of Nenana, where the relay began, and Cleveland, Ohio, where the serum run's most famous participant, a husky mix named Balto, is stuffed and displayed at a museum.
Jonathan Hayes, a Maine resident who has been working to preserve the genetic line of sled dogs driven on the run by famed musher Leonhard Seppala, is recreating the trip. Hayes left Nenana on Monday with 16 Seppala Siberian sled dogs, registered descendants of Seppala's team.
The historic trek to neutralize the diphtheria epidemic in Nome Diphtheria is an airborne disease that causes a thick, suffocating film to develop at the back of the throat; it was once a leading cause of death for children. The antitoxin used to treat it was developed in 1890, and a vaccine in 1923; it is now exceedingly rare in the U.S.
Nome, western Alaska’s largest community, had about 1,400 residents a century ago. Its most recent supply ship had arrived the previous fall, before the Bering Sea froze, without any doses of the antitoxin. Those the local doctor, Curtis Welch, had were outdated, but he wasn't worried. He hadn’t seen a case of diphtheria in the 18 years he had practiced in the area.
Within months, that changed. In a telegram, Welch pleaded with the U.S. Public Health Service to send serum: "An epidemic of diphtheria is almost inevitable here.”
The first death was a 3-year-old boy on Jan. 20, 1925, followed the next day by a 7-year-old girl. By the end of the month, there were more than 20 confirmed cases. The city was placed under quarantine.
West Coast hospitals had antitoxin doses, but it would take time to get them to Seattle and then onto a ship for Seward, an ice-free port south of Anchorage. In the meantime, enough for 30 people was found at an Anchorage hospital.
It still had to get to Nome. Airplanes with open-air cockpits were ruled out as unsuited for the weather. There were no roads or trains that reached Nome.
Instead, officials shipped the serum by rail to Nenana in interior Alaska, some 675 miles (1,086 kilometers) from Nome via the frozen Yukon River and mail trails.
Thanks to Alaska’s new telegraph lines and the spread of radio, the nation followed along, captivated, as 20 mushers — many of them Alaska Natives — with more than 150 dogs relayed the serum to Nome. They battled deep snow, whiteouts so severe they couldn’t see the dogs in front of them, and life-threatening temperatures that plunged at times to minus 60 degrees Fahrenheit (minus 51 degrees Celsius).
The antitoxin was transported in glass vials covered with padded quilts. Not a single vial broke.
Seppala, a Norwegian settler, left from Nome to meet the supply near the halfway point and begin the journey back. His team, led by his dog Togo, traveled more than 250 miles (320 kilometers) of the relay, including a treacherous stretch across frozen Norton Sound.
After about 5 1/2 days, the serum reached its destination on Feb. 2, 1925. A banner front-page headline in the San Francisco Chronicle proclaimed: “Dogs victors over blizzard in battle to succor stricken Nome.”
The official record listed five deaths and 29 illnesses. It’s likely the toll was higher; Alaska Natives were not accurately tracked.
Balto gains fame as unlikely dog to bring serum to Nome Seppala and Togo missed the limelight that went to his assistant, Gunnar Kaasen, who drove the dog team led by Balto into Nome. Balto was another of Seppala’s dogs, but was used to only haul freight after he was deemed too slow to be on a competitive team.
Balto was immortalized in movies and with statues in New York's Central Park and one in Anchorage intended as a tribute to all sled dogs. He received a bone-shaped key to the city of Los Angeles, where legendary movie actress Mary Pickford placed a wreath around his neck.
But he and several team members were eventually sold and kept in squalid conditions at a dime museum in Los Angeles. After learning of their plight, an Ohio businessman spearheaded an effort to raise money to bring them to Cleveland. After dying in 1933, Balto was mounted and placed on display at the Cleveland Museum of Natural History.
Iditarod pays homage to the serum run Today, the most famous mushing event in the world is the Iditarod Trail Sled Dog Race, which is not based on the serum run but on the Iditarod Trail, a supply route from Seward to Nome. Iditarod organizers are nevertheless marking the serum run's centennial, with a series of articles on its website and by selling replicas of the medallions each serum run musher received a century ago, race spokesperson Shannon Noonan said in an email. This year's Iditarod starts March 1.
“The Serum Run demonstrated the critical role sled dogs played in the survival and communication of remote Alaskan communities, while the Iditarod has evolved into a celebration of that tradition and Alaska’s pioneering spirit,” Noonan said.



Portugal Closes All Schools and Non-Essential Services Ahead of a Major Atlantic Storm

Heavy machinery clears the debris from a landslide along the Marocos road in Machico municipality, on the Portuguese island of Madeira, due to severe weather caused by the passage of Storm Charles, 11 November 2026. (EPA)
Heavy machinery clears the debris from a landslide along the Marocos road in Machico municipality, on the Portuguese island of Madeira, due to severe weather caused by the passage of Storm Charles, 11 November 2026. (EPA)
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Portugal Closes All Schools and Non-Essential Services Ahead of a Major Atlantic Storm

Heavy machinery clears the debris from a landslide along the Marocos road in Machico municipality, on the Portuguese island of Madeira, due to severe weather caused by the passage of Storm Charles, 11 November 2026. (EPA)
Heavy machinery clears the debris from a landslide along the Marocos road in Machico municipality, on the Portuguese island of Madeira, due to severe weather caused by the passage of Storm Charles, 11 November 2026. (EPA)

Portugal closed all schools and shuttered non-essential public services on Wednesday as a major Atlantic storm headed for the country's mainland.

Streets remained largely deserted ahead of the arrival of Storm Charles after the government told people to stay at home as heavy rain and rough seas were expected to batter the Portuguese coast, with wind gusts of up to 140 kph (85 mph).

It was the first time in living memory that Portugal’s roughly 8,000 schools had canceled classes nationwide over a storm forecast.

Buses without passengers drove through the country's capital, Lisbon, where some streets flooded due to clogged drains. A national supermarket chain closed its stores, while an international technology conference in Lisbon attended by around 70,000 people called off the day's events.

In January, the country's center-right government faced harsh criticism for its weak response when Storm Kristin hit central Portugal, felling thousands of trees and causing widespread property damage that is still being repaired.

The brunt of Storm Charles was expected to hit the Atlantic coast on Wednesday afternoon and evening, coming from the southwest after it had struck the Portuguese island of Madeira on Tuesday with 130 kph (81 mph) winds.


Once the World's Fastest, Ocean Liner Will Become Largest Artificial Reef

The S.S. United States crossed the Atlantic more than 800 times. (Getty Images)
The S.S. United States crossed the Atlantic more than 800 times. (Getty Images)
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Once the World's Fastest, Ocean Liner Will Become Largest Artificial Reef

The S.S. United States crossed the Atlantic more than 800 times. (Getty Images)
The S.S. United States crossed the Atlantic more than 800 times. (Getty Images)

An ocean liner that is longer than the Titanic and was once the fastest on the seas is headed to a final home on the floor of the Gulf of Mexico as the world's largest artificial reef.

The S.S. United States is scheduled to be sunk Wednesday off the coast of the Florida Panhandle, fulfilling a long-planned $13.5 million project aimed at attracting more divers and fishing enthusiasts to the area while creating a home for tuna, marlin and swordfish.

The project will keep what had been a technological marvel when it made its maiden voyage in 1952 from becoming scrap metal.

The S.S. United States crossed the Atlantic more than 800 times, carrying old Hollywood stars like Grace Kelly and Elizabeth Taylor. Other passengers have included President John F. Kennedy and Britain’s former King Edward VIII. In 1968, a young Bill Clinton took it when he went to Oxford University, decades before he was elected president.

In preparation for the sinking, organizers removed the 65-foot smokestacks and plan to have them anchor a new museum that celebrates the ship. Once aboard, passengers were treated to dinners that included caviar, roast duckling, smoked ox tongue and Calf's Head en Tortue.

“It was our goal to make sure that she wasn’t lost forever,” said David Lawrence, a member of the board for the S.S. United States Conservancy, which is dedicated to preserving the ship.

The ship will be sunk without using explosives

Federal environmental and explosives rules prevent Okaloosa County, Florida, and its contractor from using explosives to scuttle the ship, said Nick Tomecek, the county's spokesperson. Concerns about inclement weather prompted officials to move up the sinking by a day.

The S.S. United States has pipes that pulled seawater into tanks as part of the system that cooled its boilers, he said, and those tanks have been removed so that once the valves are opened, water will flood the hull. Workers also have cut 10-foot by 10-foot holes in the decks, and more than 400 portholes have been removed.

The ship is to sink in about 180 feet (55 meters) of water, with its top deck about 60 feet (18 meters) below the surface — shallow enough that inexperienced divers can visit. It will settle on the floor of the waters about 25 miles (40 kilometers) southwest of Destin, between Panama City and Pensacola.

Larger than the Titanic, the ship's first voyage set a speed record

More than 3,000 workers helped build the S.S. United States in 1950 and 1951 in Virginia. An Associated Press reporter and President Harry Truman's daughter, Margaret, were among 1,700 passengers for the first voyage.

The ship's average speed for that trip was almost 41 miles (66 kilometers) per hour, besting a record set by Britain's R.M.S. Queen Mary in 1938 by 4.5 miles (7.2 kilometers) per hour, according to the AP's dispatch.

The S.S. United States set the record even though its journey ended in the face of a full gale that reached 69 miles (111 kilometers) per hour — “so strong it blew a ping pong table off the deck,” AP reported.

At 990 feet (302 meters), the ship is 108 feet (33 meters) longer than the ill-fated Titanic, which hit an iceberg and sank on its first voyage across the Atlantic.

“She really embodies and expresses this country’s best,” said Susan Gibbs, the granddaughter of the ship's designer. “She represents pride and resilience and strength and beauty.”

The ship's resting place has many artificial reefs

About 500 artificial reefs are located in the waters near where the S.S. United States will rest, Tomecek said.

Previously, the largest artificial reef came from the 2006 scuttling of an aircraft carrier, the USS Oriskany in the Gulf off of Pensacola — near enough to the S.S. United States site that an experienced diver could visit both in the same day, Tomecek said. The Oriskany, launched in 1950, was 911 feet (278 meters) in length.

“We're trying to be the best diving destination in the world,” Tomecek said.

The ship was decommissioned in 1969. Attempts by a hotel magnate and Norwegian Cruise Lines to use the ship never floated, and from 1996 until recently, it sat along a dock in Philadelphia.

“I’m just so happy that we are able to save parts of her,” Gibbs said.


Medical Breakthrough for People with Same Disorder as Celine Dion

Celine Dion. (AFP)
Celine Dion. (AFP)
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Medical Breakthrough for People with Same Disorder as Celine Dion

Celine Dion. (AFP)
Celine Dion. (AFP)

People suffering from stiff person syndrome (SPS), which affects Celine Dion, the singer, could soon benefit from a new medicine which improves symptoms.

Patients in the US were given a one-off immunotherapy drug in a clinical trial, resulting in two individuals regaining function related to everyday life that had been lost to SPS, according to The Telegraph.

SPS is a rare neurological disorder that gets progressively worse, and symptoms include stiffness in the body, spine, arms and legs.

The Telegraph said patients were given chimeric antigen receptor T-cell (CAR-T) therapy, which teaches the body’s immune system to recognize and attack deadly cells causing disease.

CAR-T therapy is already approved on the NHS for some illnesses, including certain types of cancer, and research is ongoing.

One patient in the US trial, Jonathan Walden, had reached the point where walking and basic daily tasks required help from his family.

After CAR-T therapy, he has now returned to work and normal activities.

“I can go to work every single day. I can do everything I did before. I go hunting, I can go fishing,” he said.

Dr. Anastasia Zekeridou, a neurologist and researcher at Mayo Clinic in Rochester in the US, which led the trial, said: “What was most striking was the degree of improvement we saw in some patients.”

“With existing treatments, we may be able to improve symptoms, but we very rarely see patients return to their previous level of function,” she said, adding that these early results are very encouraging, and the key question now is whether those improvements will be sustained over time.

Dr. Sean Pittock, chairman of the department of neurology at Mayo Clinic, said: “CAR-T therapy has already transformed the treatment of some cancers, and we are now beginning to see its potential in autoimmune neurologic diseases.”

Pittock also explained that the results in stiff person syndrome offer tremendous hope, not only for people living with this disease but potentially for patients with other immune-mediated neurologic conditions where effective treatment options remain limited.

“There is still much we need to learn, but this opens an exciting new avenue for the field,” he said.

Dion, the Canadian vocalist, announced she was diagnosed with stiff person syndrome in December 2022.

In an Instagram video, she told fans the condition had affected “every aspect of my daily life,” including harming her voice.

SPS affects an estimated 8,000 people worldwide. The British Neurological Surveillance Unit identified 119 confirmed cases in the UK across a five-year tracking period between 2000 and 2005.

Scientists believe it can become a widespread syndrome that affects multiple parts of the body and involves the brain, brainstem and spinal cord.