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Menu Signed by Mao Zedong Brings a Quarter Million Dollars at Auction

This photo provided by RR Auction shows an official menu for a state banquet signed by former Chinese leader Mao Zedong that has been auctioned for $275,000. (RR Auction via AP)
This photo provided by RR Auction shows an official menu for a state banquet signed by former Chinese leader Mao Zedong that has been auctioned for $275,000. (RR Auction via AP)
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Menu Signed by Mao Zedong Brings a Quarter Million Dollars at Auction

This photo provided by RR Auction shows an official menu for a state banquet signed by former Chinese leader Mao Zedong that has been auctioned for $275,000. (RR Auction via AP)
This photo provided by RR Auction shows an official menu for a state banquet signed by former Chinese leader Mao Zedong that has been auctioned for $275,000. (RR Auction via AP)

An official menu for a state banquet that bears the signature of former Chinese leader Mao Zedong has been auctioned for $275,000.
Boston-based RR Auction said the menu auctioned Wednesday was for a banquet held in Beijing on October 19, 1956, and commemorated the first state visit to China by Pakistan's Prime Minister Huseyn Shaheed Suhrawardy.
The menu was signed in fountain pen by six influential Chinese statesmen, including Mao and Premier Zhou Enlai. The banquet featured foods from both nations and included delicacies such as “Consommé of Swallow Nest and White Agaric,” “Shark’s Fin in Brown Sauce,” and “Roast Peking Duck.”
“To hold a menu signed by Mao Zedong and Zhou Enlai is to hold a piece of the past – a piece that tells a story of diplomatic engagement, cultural exchange, and the forging of friendships that have endured through the decades,” Bobby Livingston, executive vice president at RR Auction, said in a statement.
Other items auctioned off included a fully operational World War II-era Enigma coding machine for $206,253, a Thomas Edison-signed document for a light bulb patent for $22,154, and a check signed by Steve Jobs to Radio Shack was sold for $46,063.

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Blood Tests Allow 30-year Estimates of Women's Cardio Risks, New Study Says

A woman jogs in a park in Saint-Sebastien-sur-Loire near Nantes, France January 19, 2024. REUTERS/Stephane Mahe/File Photo Purchase Licensing Rights
A woman jogs in a park in Saint-Sebastien-sur-Loire near Nantes, France January 19, 2024. REUTERS/Stephane Mahe/File Photo Purchase Licensing Rights
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Blood Tests Allow 30-year Estimates of Women's Cardio Risks, New Study Says

A woman jogs in a park in Saint-Sebastien-sur-Loire near Nantes, France January 19, 2024. REUTERS/Stephane Mahe/File Photo Purchase Licensing Rights
A woman jogs in a park in Saint-Sebastien-sur-Loire near Nantes, France January 19, 2024. REUTERS/Stephane Mahe/File Photo Purchase Licensing Rights

Women’s heart disease risks and their need to start taking preventive medications should be evaluated when they are in their 30s rather than well after menopause as is now the practice, said researchers who published a study on Saturday.

Presenting the findings at the European Society of Cardiology annual meeting in London, they said the study showed for the first time that simple blood tests make it possible to estimate a woman’s risk of cardiovascular disease over the next three decades.

"This is good for patients first and foremost, but it is also important information for (manufacturers of) cholesterol lowering drugs, anti-inflammatory drugs, and lipoprotein(a)lowering drugs - the implications for therapy are broad," said study leader Dr. Paul Ridker of Brigham and Women’s Hospital in Boston, Reuters reported.

Current guidelines “suggest to physicians that women should generally not be considered for preventive therapies until their 60s and 70s. These new data... clearly demonstrate that our guidelines need to change,” Ridker said. “We must move beyond discussions of 5 or 10 year risk."

The 27,939 participants in the long-term Women’s Health Initiative study had blood tests between 1992 and 1995 for low density lipoprotein cholesterol (LDL-C or “bad cholesterol”), which are already a part of routine care.

They also had tests for high-sensitivity C-reactive protein (hsCRP) - a marker of blood vessel inflammation - and lipoprotein(a), a genetically determined type of fat.

Compared to risks in women with the lowest levels of each marker, risks for major cardiovascular events like heart attacks or strokes over the next 30 years were 36% higher in women with the highest levels of LDL-C, 70% higher in women with the highest levels of hsCRP, and 33% higher in those with the highest levels of lipoprotein(a).

Women in whom all three markers were in the highest range were 2.6 times more likely to have a major cardiovascular event and 3.7 times more likely to have a stroke over the next three decades, according to a report of the study in The New England Journal of Medicine published to coincide with the presentation at the meeting.

“The three biomarkers are fully independent of each other and tell us about different biologic issues each individual woman faces,” Ridker said.

“The therapies we might use in response to an elevation in each biomarker are markedly different, and physicians can now specifically target the individual person’s biologic problem.”

While drugs that lower LDL-C and hsCRP are widely available - including statins and certain pills for high blood pressure and heart failure - drugs that reduce lipoprotein(a) levels are still in development by companies, including Novartis , Amgen , Eli Lilly and London-based Silence Therapeutics.

In some cases, lifestyle changes such as exercising and quitting smoking can be helpful.

Most of the women in the study were white Americans, but the findings would likely “have even greater impact among Black and Hispanic women for whom there is even a higher prevalence of undetected and untreated inflammation,” Ridker said.

“This is a global problem,” he added. “We need universal screening for hsCRP ... and for lipoprotein(a), just as we already have universal screening for cholesterol.”