Ozempic Hailed as 'Fountain of Youth' that Slows Aging

The is available under the brand names Wegovy and Ozempic (Photo by Reuters)
The is available under the brand names Wegovy and Ozempic (Photo by Reuters)
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Ozempic Hailed as 'Fountain of Youth' that Slows Aging

The is available under the brand names Wegovy and Ozempic (Photo by Reuters)
The is available under the brand names Wegovy and Ozempic (Photo by Reuters)

The anti-obesity drug Ozempic could slow down ageing and has “far-reaching benefits” beyond what was imagined, researchers have suggested.

Multiple studies have found semaglutide (available under the brand names Wegovy and Ozempic) reduced the risk of death in people who were obese or overweight and had cardiovascular disease without diabetes, The Independent reported.

Responding to research published in JACC, the flagship journal of the American College of Cardiology, Professor Harlan M Krumholz from the Yale School of Medicine, said: “Semaglutide, perhaps by improving cardiometabolic health, has far-reaching benefits beyond what we initially imagined.”

He added: “These ground-breaking medications are poised to revolutionise cardiovascular care and could dramatically enhance cardiovascular health.”

Multiple reports also quoted Professor Krumholz saying: “Is it a fountain of youth?”

He said: “I would say if you’re improving someone’s cardiometabolic health substantially, then you are putting them in a position to live longer and better.

“It’s not just avoiding heart attacks. These are health promoters. It wouldn’t surprise me that improving people’s health this way actually slows down the ageing process.”

The studies, presented at the European Society of Cardiology Conference 2024 in London, were produced from the Select trial which studied 17,604 people aged 45 or older who were overweight or obese and had established cardiovascular disease but not diabetes.

They received 2.4 mg of semaglutide or a placebo and were tracked for more than three years.

A total of 833 participants died during the study with 5 percent of the deaths were related to cardiovascular causes and 42 per cent from others.

Infection was the most common cause death beyond cardiovascular, but it occurred at a lower rate in the semaglutide group than the placebo group.

People using the weight-loss drug were just as likely to catch Covid-19, but they were less likely to die from it – 2.6 percent dying among those on semaglutide versus 3.1 per cent on the placebo.

Researchers found women experienced fewer major adverse cardiovascular events, but semaglutide “consistently reduced the risk” of adverse cardiovascular outcomes regardless of sex.

Dr Benjamin Scirica, lead author of one of the studies and a professor of cardiovascular medicine at Harvard Medical School, said: “The robust reduction in non-cardiovascular death, and particularly infections deaths, was surprising and perhaps only detectable because of the Covid-19-related surge in non-cardiovascular deaths.

“These findings reinforce that overweight and obesity increases the risk of death due to many etiologies, which can be modified with potent incretin-based therapies like semaglutide.”

Dr Jeremy Samuel Faust, an emergency medicine physician at Brigham and Women’s Hospital, praised the researchers for adapting the study to look at Covid-19 when the pandemic started.

He said the findings that the weight-loss drug to reduce Covid-19 mortality rates were “akin to a vaccine against the indirect effects of a pathogen.”



King Salman Bin Abdulaziz Royal Reserve Development Authority Joins IUCN Green List

The Green List provides crucial guidelines for conservation and involving stakeholders in sustainable development processes - SPA
The Green List provides crucial guidelines for conservation and involving stakeholders in sustainable development processes - SPA
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King Salman Bin Abdulaziz Royal Reserve Development Authority Joins IUCN Green List

The Green List provides crucial guidelines for conservation and involving stakeholders in sustainable development processes - SPA
The Green List provides crucial guidelines for conservation and involving stakeholders in sustainable development processes - SPA

The King Salman Bin Abdulaziz Royal Reserve Development Authority has announced its inclusion in the International Union for Conservation of Nature (IUCN) Green List.
This recognition follows a comprehensive assessment of the reserve by IUCN experts, who evaluated the authority's environmental and developmental accomplishments, as well as its engagement with the community and preservation efforts, SPA reported.
Authority CEO Abdullah Al-Amer emphasized the significance of this milestone, stating: "Since its establishment, the authority has pursued strategies, development plans, and innovative initiatives to fulfill its core objectives. Through these endeavors, we have successfully met all the key criteria and indicators for joining the IUCN Green List."
Al-Amer attributed this to the support lent by the Saudi leadership and the guidance from Minister of Interior and Chairman of the authority Prince Abdulaziz bin Saud bin Naif bin Abdulaziz.
Inclusion in the Green List adds to the authority's local and global successes, including receiving the Biodiversity Certificate and designating five critical bird sites within the King Salman bin Abdulaziz Royal Reserve.
Al-Amer stressed that making it on the list is testimony to an effective reserve management and focus on natural resource growth; it now facilitates the growth of over 550 plant species.
The authority's initiatives include planting 2.4 million native tree and shrub seedlings, as well as four tons of local seeds like yarrow (Achillea millefolium), Artemisia, and Haloxylon.
Efforts have been made to restore 250,000 hectares of degraded habitats and relocate 1,235 wildlife species like Arabian oryx, sand gazelles, Arabian gazelles, and Arabian leopards in the reserve.
The authority's achievements are due to its strategic objectives; being on the Green List is a key milestone.
This authority is determined to manage protected areas through sustainable programs focused on environmental conservation, community engagement, and sustainable development, in line with international standards.