Nobel Prize in Medicine Honors Two Americans for Discovery of MicroRNA

Nobel Committee Secretary General Thomas Perlmann speaks to the media in front of a picture of this year's laureates Victor Ambros and Gary Ruvkum during the announcement of the winners of the 2024 Nobel Prize in Physiology or Medicine at the Karolinska Institute in Stockholm on October 7, 2024. (AFP)
Nobel Committee Secretary General Thomas Perlmann speaks to the media in front of a picture of this year's laureates Victor Ambros and Gary Ruvkum during the announcement of the winners of the 2024 Nobel Prize in Physiology or Medicine at the Karolinska Institute in Stockholm on October 7, 2024. (AFP)
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Nobel Prize in Medicine Honors Two Americans for Discovery of MicroRNA

Nobel Committee Secretary General Thomas Perlmann speaks to the media in front of a picture of this year's laureates Victor Ambros and Gary Ruvkum during the announcement of the winners of the 2024 Nobel Prize in Physiology or Medicine at the Karolinska Institute in Stockholm on October 7, 2024. (AFP)
Nobel Committee Secretary General Thomas Perlmann speaks to the media in front of a picture of this year's laureates Victor Ambros and Gary Ruvkum during the announcement of the winners of the 2024 Nobel Prize in Physiology or Medicine at the Karolinska Institute in Stockholm on October 7, 2024. (AFP)

The Nobel Prize in medicine was awarded Monday to Americans Victor Ambros and Gary Ruvkun for their discovery of microRNA, a fundamental principle governing how gene activity is regulated.

The Nobel Assembly said that their discovery is “proving to be fundamentally important for how organisms develop and function.”

Ambrose performed the research that led to his prize at Harvard University. He is currently a professor of natural science at the University of Massachusetts Medical School. Rackham’s research was performed at Massachusetts General Hospital and the Harvard Medical School, where he’s a professor of genetics, said Thomas Perlmann, Secretary-General of the Nobel Committee.

Last year, the Nobel Prize in Physiology or Medicine went to Hungarian-American Katalin Karikó and American Drew Weissman for discoveries that enabled the creation of mRNA vaccines against COVID-19 that were critical in slowing the pandemic.

The prize carries a cash award of 11 million Swedish kronor ($1 million) from a bequest left by the prize’s creator, Swedish inventor Alfred Nobel.

The announcement launched this year’s Nobel prizes award season.

Nobel announcements continue with the physics prize on Tuesday, chemistry on Wednesday and literature on Thursday. The Nobel Peace Prize will be announced Friday and the Nobel Memorial Prize in Economic Sciences on Oct. 14.

The laureates are invited to receive their awards at ceremonies on Dec. 10, the anniversary of Nobel’s death.



Survivor of Rare Rapid-ageing Disease Progeria Dies at 28

Progeria, also known as Hutchinson–Gilford syndrome (HGPS), causes people to age rapidly, leading them to appear older than they are - (Photo by AFP)
Progeria, also known as Hutchinson–Gilford syndrome (HGPS), causes people to age rapidly, leading them to appear older than they are - (Photo by AFP)
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Survivor of Rare Rapid-ageing Disease Progeria Dies at 28

Progeria, also known as Hutchinson–Gilford syndrome (HGPS), causes people to age rapidly, leading them to appear older than they are - (Photo by AFP)
Progeria, also known as Hutchinson–Gilford syndrome (HGPS), causes people to age rapidly, leading them to appear older than they are - (Photo by AFP)

Sammy Basso, who was the longest living survivor of the rare genetic disease progeria, has died at the age of 28, the Italian Progeria Association said on Sunday.

Progeria, also known as Hutchinson–Gilford syndrome (HGPS), causes people to age rapidly, leading them to appear older than they are, with a reduced quality of life and a life expectancy of only 13.5 years without treatment, the association's website said.

It affects one in every eight million people born, and has a worldwide incidence of one in every 20 million, Reuters reported.

Born in 1995 in Schio, in the northern Italian region of Veneto, Basso was diagnosed with progeria at the age of two. In 2005, he and his parents founded the Italian Progeria Association.

He became famous through the National Geographic documentary "Sammy's Journey," which recounts his journey along Route 66 in the United States, from Chicago to Los Angeles, with his parents and one of his best friends, Riccardo.

"Today our light, our guide, has gone out. Thank you Sammy for making us part of this wonderful life," the association wrote on its Instagram page.

There are only 130 recognised cases of classic progeria worldwide, of which four are in Italy.

However, the Italian Progeria Association estimated there could be as many as 350 cases as they can be difficult to trace especially in developing countries.