WHO Calls for Immediate Action as Report Shows 10% Rise in Child TB Infections in European Region 

This 2006 electron microscope image provided by the Centers for Disease Control and Prevention shows Mycobacterium tuberculosis bacteria, which causes the disease tuberculosis. (Janice Carr/CDC via AP) 
This 2006 electron microscope image provided by the Centers for Disease Control and Prevention shows Mycobacterium tuberculosis bacteria, which causes the disease tuberculosis. (Janice Carr/CDC via AP) 
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WHO Calls for Immediate Action as Report Shows 10% Rise in Child TB Infections in European Region 

This 2006 electron microscope image provided by the Centers for Disease Control and Prevention shows Mycobacterium tuberculosis bacteria, which causes the disease tuberculosis. (Janice Carr/CDC via AP) 
This 2006 electron microscope image provided by the Centers for Disease Control and Prevention shows Mycobacterium tuberculosis bacteria, which causes the disease tuberculosis. (Janice Carr/CDC via AP) 

Tuberculosis (TB) infections among children in the European region rose 10% in 2023, indicating ongoing transmission and the need for immediate public health measures to control the spread, the World Health Organization said on Monday.

WHO's European region, which comprises 53 countries in Europe and Central Asia, reported more than 7,500 cases among children under 15 years of age in 2023, an increase of over 650 cases compared to 2022.

"The worrying rise in children with TB serves as a reminder that progress against this preventable and curable disease remains fragile," said Hans Henri Kluge, WHO's Regional Director for Europe.

Askar Yedilbayev, regional TB advisor for WHO's European region, said in an interview that a rise in overall cases might indicate improved diagnoses. However, it could also result from increased cross-border movement due to the Russia-Ukraine war, the two countries with the highest disease burden in the region.

Children under 15 years of age made up 4.3% of all TB cases in the European Union, a joint report by the WHO and the European Center for Disease Prevention and Control showed.

This shows an increase in cases in this age group for the third consecutive year, which Yedilbayev said was a "worrisome scenario".

WHO has previously warned that funding cuts from global donors will undo progress in controlling TB infections across low- and middle-income countries. These cuts can hurt TB programs in non-EU countries, fueling a rise of hard-to-treat strains, the agency said.

Several local, on-ground workforces have been hurt from the funding cuts, and the supply of diagnostics and treatments remains at risk, said Yedilbayev.

TB, among the top 10 causes of death worldwide, is a potentially fatal bacterial infection that mainly affects the lungs and spreads through coughing or sneezing.



A Set of 1st Editions of Shakespeare's Plays Could Fetch $6 million at Auction

This photo issued by Sotheby's on Wednesday April 23, 2025, shows The First Folio of William Shakespeare, which contains 36 of Shakespeare's plays, and is "the most significant publication in the history of English literature". It is one of four folios which are due to go on sale at Sotheby's in London on May 23, where they are expected to fetch between £3.5 million and £4.5 million. (Sotheby's via AP)
This photo issued by Sotheby's on Wednesday April 23, 2025, shows The First Folio of William Shakespeare, which contains 36 of Shakespeare's plays, and is "the most significant publication in the history of English literature". It is one of four folios which are due to go on sale at Sotheby's in London on May 23, where they are expected to fetch between £3.5 million and £4.5 million. (Sotheby's via AP)
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A Set of 1st Editions of Shakespeare's Plays Could Fetch $6 million at Auction

This photo issued by Sotheby's on Wednesday April 23, 2025, shows The First Folio of William Shakespeare, which contains 36 of Shakespeare's plays, and is "the most significant publication in the history of English literature". It is one of four folios which are due to go on sale at Sotheby's in London on May 23, where they are expected to fetch between £3.5 million and £4.5 million. (Sotheby's via AP)
This photo issued by Sotheby's on Wednesday April 23, 2025, shows The First Folio of William Shakespeare, which contains 36 of Shakespeare's plays, and is "the most significant publication in the history of English literature". It is one of four folios which are due to go on sale at Sotheby's in London on May 23, where they are expected to fetch between £3.5 million and £4.5 million. (Sotheby's via AP)

A set of the first four editions of William Shakespeare’s collected works is expected to sell for up to 4.5 million pounds ($6 million) at auction next month.

Sotheby’s auction house announced the sale on Wednesday, Shakespeare's 461st birthday. It said the May 23 sale will be the first time since 1989 that a set of the First, Second, Third and Fourth Folios has been offered at auction as a single lot.

The auction house estimated the sale price at between 3.5 million and 4.5 million pounds.

After Shakespeare’s death in 1616, his plays were collected into a single volume by his friends John Heminges and Henry Condell, actors and shareholders in the playwright’s troupe, the King’s Men, The AP news reported.

The First Folio — fully titled “Mr. William Shakespeares Comedies, Histories & Tragedies” — contained 36 plays, of which half were published there for the first time. Without the book, scholars say, plays including “Macbeth,” “The Tempest” and “Twelfth Night” might have been lost. Sotheby’s called the volume “without question the most significant publication in the history of English literature.”

About 750 copies were printed in 1623, of which about 230 are known to survive. All but a few are in museums, universities or libraries. One of the few First Folios in private hands sold for $9.9 million at an auction in 2020.

The First Folio proved successful enough that a an updated edition, the Second Folio, was published in 1632, a third in 1663 and a fourth in 1685.

Although the First Folio is regarded as the most valuable, the third is the rarest, with 182 copies known to survive. It is believed the third book’s rarity is because some of the stock was destroyed in the Great Fire of London in 1666.

The Third Folio included seven additional plays, but only one – “Pericles, Prince of Tyre” – is believed to be by Shakespeare.