Iran’s Supreme Leader Opens Door to Negotiations with US over Tehran’s Nuclear Program

A handout photo made available by the supreme leader office shows Iranian Supreme Leader Ali Khamenei (L) speaking as Iranian President Masoud Pezeshkian looks on, during a meeting with the new Iranian government in Tehran, Iran, 27 August 2024. (EPA/Iranian Supreme Leader Office Handout)
A handout photo made available by the supreme leader office shows Iranian Supreme Leader Ali Khamenei (L) speaking as Iranian President Masoud Pezeshkian looks on, during a meeting with the new Iranian government in Tehran, Iran, 27 August 2024. (EPA/Iranian Supreme Leader Office Handout)
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Iran’s Supreme Leader Opens Door to Negotiations with US over Tehran’s Nuclear Program

A handout photo made available by the supreme leader office shows Iranian Supreme Leader Ali Khamenei (L) speaking as Iranian President Masoud Pezeshkian looks on, during a meeting with the new Iranian government in Tehran, Iran, 27 August 2024. (EPA/Iranian Supreme Leader Office Handout)
A handout photo made available by the supreme leader office shows Iranian Supreme Leader Ali Khamenei (L) speaking as Iranian President Masoud Pezeshkian looks on, during a meeting with the new Iranian government in Tehran, Iran, 27 August 2024. (EPA/Iranian Supreme Leader Office Handout)

Iran's supreme leader opened the door Tuesday to renewed negotiations with the United States over his country's rapidly advancing nuclear program, telling its civilian government there was “no harm" in engaging with its “enemy.”

Ali Khamenei's remarks set clear red lines for any talks taking place under the government of reformist President Masoud Pezeshkian and renewed his warnings that Washington wasn't to be trusted.

But his comments mirror those around the time of Iran's 2015 nuclear deal with world powers, which saw Tehran's nuclear program greatly curtailed in exchange for the lifting of economic sanctions. Yet it remains unclear just how much room Pezeshkian will have to maneuver, particularly as tensions remain high in the wider Middle East over the Israel-Hamas war and as the US prepares for a presidential election in November.

“This does not mean that we cannot interact with the same enemy in certain situations,” Khamenei said, according to a transcript on his official website. "There is no harm in that, but do not place your hopes in them.”

Khamenei, who has the final say on all state matters, also warned Pezeshkian's Cabinet, “Do not trust the enemy.”

Khamenei, 85, has occasionally urged talks or dismissed them with Washington after then-President Donald Trump unilaterally withdrew the United States from the deal in 2018.

There have been indirect talks between Iran and the US in recent years mediated by Oman and Qatar, two of the United States' Middle East interlocutors when it comes to Iran. Khamenei's remarks came a day after Qatar's prime minister visited the country.

Asked for comment, the US State Department told The Associated Press: “We will judge Iran’s leadership by their actions, not their words.”

“We have long said that we ultimately view diplomacy as the best way to achieve an effective, sustainable solution with regard to Iran’s nuclear program,” it said. “However, we are far away from anything like that right now given Iran’s escalations across the board, including its nuclear escalations and its failure to cooperate" with the International Atomic Energy Agency, the United Nations nuclear watchdog.

“If Iran wants to demonstrate seriousness or a new approach, they should stop nuclear escalations and start meaningfully cooperating with the IAEA,” it said.

Since the deal's collapse, Iran has abandoned all limits that the deal put on its program, and enriches uranium to up to 60% purity — near weapons-grade levels of 90%.

Surveillance cameras installed by the IAEA have been disrupted, while Iran has barred some of the Vienna-based agency’s most experienced inspectors. Iranian officials also have increasingly threatened that they could pursue atomic weapons.

Meanwhile, tensions between Iran and Israel have hit a new high during the Israel-Hamas war in the Gaza Strip. Tehran launched an unprecedented drone-and-missile attack on Israel in April after years of a shadow war between the two countries reached a climax with Israel’s apparent attack on an Iranian consular building in Syria that killed two Iranian generals and others.

The assassination in Tehran of Hamas leader Ismail Haniyeh also prompted Iran to threaten to retaliate against Israel.

Pezeshkian, a former lawmaker who won the presidency after a May helicopter crash killed hard-line President Ebrahim Raisi, campaigned in part on a promise to reengage the West with negotiations.

Khamenei's remarks as Iran's paramount leader could provide him with the political cover to do so. Pezeshkian's new foreign minister, Abbas Araghchi, was deeply involved in negotiations on the 2015 deal.

“After doing everything we can, a tactical retreat might sometimes be necessary, but we should not abandon our goals or opinions at the first sign of difficulty,” Khameini also said Tuesday, the second time in recent days he's referred to a “tactical retreat” amid the tensions.

However, it's not just Iran that's facing a new presidency. The US will hold a presidential election on Nov. 5, with Vice President Kamala Harris and Trump as the leading candidates. Iran has been concerned about Trump’s return to power.

While the US engaged in indirect talks with Iran under President Joe Biden, it remains unclear how that would carry over to a possible Harris administration. Harris, in a speech to the Democratic National Convention last week, said: “I will never hesitate to take whatever action is necessary to defend our forces and our interests against Iran and Iran-backed terrorists.”

The RANE Network, a risk-intelligence firm, said if Harris wins, “the likelihood of a deal will rise as the Israel-Hamas war winds down.”

“Once negotiations begin, Iran will likely demand more protections regarding a potential US withdrawal from a new deal after the United States walked away from the previous deal in 2018,” RANE said in an analysis Tuesday.

“Because of concerns about the sustainability of any new deal, Iran is also less likely to offer as many nuclear concessions, like the dismantling of more advanced centrifuges, since Iran would want to be able to spin up its nuclear program as fast as possible in the event of another US exit from the new deal.”

Tuesday's meeting between Khamenei and Pezeshkian's Cabinet included an appearance by former Foreign Minister Mohammad Javad Zarif, who helped Iran reach the 2015 deal. After the meeting, Zarif said in an online message that he would continue to serve as a vice president in Pezeshkian's administration after earlier publicly resigning over the makeup of the Cabinet.



Africa’s Mpox Outbreaks Result from Neglect and World’s Inability to Stop Epidemics, Experts Say

An mpox patient is injected with an intravenous treatment at the Kavumu hospital, 30 km north of Bukavu in eastern Democratic Republic of Congo, August 24, 2024. (AFP)
An mpox patient is injected with an intravenous treatment at the Kavumu hospital, 30 km north of Bukavu in eastern Democratic Republic of Congo, August 24, 2024. (AFP)
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Africa’s Mpox Outbreaks Result from Neglect and World’s Inability to Stop Epidemics, Experts Say

An mpox patient is injected with an intravenous treatment at the Kavumu hospital, 30 km north of Bukavu in eastern Democratic Republic of Congo, August 24, 2024. (AFP)
An mpox patient is injected with an intravenous treatment at the Kavumu hospital, 30 km north of Bukavu in eastern Democratic Republic of Congo, August 24, 2024. (AFP)

The rising mpox outbreaks in Africa that triggered the World Health Organization’s emergency declaration are largely the result of decades of neglect and the global community’s inability to stop sporadic epidemics among a population with little immunity against the smallpox-related disease, leading African scientists said Tuesday.

According to Dr. Dimie Ogoina, who chaired WHO’s mpox emergency committee, negligence has led to a new, more transmissible version of the virus emerging in countries with few resources to stop outbreaks.

Mpox, also known as monkeypox, had been spreading mostly undetected for years in Nigeria and elsewhere before the disease prompted the 2022 outbreak in more than 70 countries, Ogoina said at a virtual news conference.

“What we are witnessing in Africa now is different from the global outbreak in 2022,” he said. Mpox in Africa is now being spread via sexual transmission as well as through close contact among children, pregnant women and other vulnerable groups.

And while most people over 50 were likely vaccinated against smallpox — which may provide some protection against mpox — that is not the case for Africa’s mostly young population, who Ogoina said were mostly susceptible.

Mpox belongs to the same family of viruses as smallpox but causes milder symptoms like fever and body aches. It mostly spreads through close skin-to-skin contact, including sex. People with more serious cases can develop prominent blisters on the face, hands, chest and genitals.

Earlier this month, WHO declared the surging mpox outbreaks in Congo and 11 other countries in Africa to be a global emergency.

On Tuesday, the Africa Centers for Disease Control and Prevention said there were more than 22,800 mpox cases and 622 deaths on the continent and that infections had jumped 200% in the last week. The majority of cases and deaths are in Congo, where most mpox infections are in children under 15.

Dr. Placide Mbala-Kingebeni, a Congolese scientist who helped identify the newest version of mpox, said diagnostic tests being used in the country did not always pick it up, making it hard to track the variant’s spread.

In May, Mbala-Kingebeni, who heads a lab at Congo’s National Institute for Biomedical Research, published research showing a new form of mpox that may be less deadly but more transmissible. The noted mutations suggested it was “more adapted to human transmission,” he said, but the lack of tests in Congo and elsewhere complicated efforts to monitor outbreaks.

The new variant has been detected in four other African countries as well as Sweden, where health officials said they have identified the first case of a person this month with the more infectious form of mpox. The person had been infected during a stay in Africa.

WHO said that available data to date does not suggest that the new form of mpox is more dangerous but that research is ongoing.

Marion Koopmans, a virologist at Erasmus Medical Centre in the Netherlands who has been studying mpox, said scientists were now seeing some significant impacts of the disease, noting that pregnant women were miscarrying or losing their fetuses and that some babies were being born infected with mpox.

Ogoina, a professor of infectious diseases at Niger Delta University in Nigeria, said that in the absence of vaccines and drugs, African health workers should focus on providing supportive care, like ensuring patients have enough to eat and are given mental health support, given the stigma that often comes with mpox.

“It’s very, very unfortunate that we have had mpox for 54 years and we are only now thinking about therapeutics,” he said.

Mbala-Kingebeni said strategies previously used to stop Ebola outbreaks in Africa might help, given the limited numbers of shots expected. He said authorities have estimated Africa needs about 10 million doses but might only receive about 500,000 — and it’s unclear when they might arrive.

“Finding a case and vaccinating around the case, like we did with Ebola, might help us target the hot spots,” he said.

Koopmans of the Erasmus Medical Centre said that given the urgent need for vaccines in Africa, waiting for more doses to be produced was unrealistic.

“The short term (question) really is about, who has vaccines and where are they to be best used next?" she said.

Spain’s health ministry announced Tuesday that it would dip into its mpox vaccine stockpile to donate 20% of its supply, about 500,000 doses, to African countries battling mpox.

“We consider it senseless to accumulate vaccines where they are not needed,” Spain’s health ministry said in a statement, adding Spain will recommend to the European Commission to propose that all member states also donate 20% of their vaccine stock.

Spain's donation alone is more than what the European Union, vaccine Bavarian Nordic and the US have pledged. Last week, Africa CDC said that the EU and Bavarian Nordic had promised 215,000 mpox vaccines while the US said it had donated 50,000 doses of the same vaccine to Congo. Japan has also donated some doses to Congo.

The Africa CDC said it does not expect any vaccines to land on the continent until next month when political and health leaders meet to discuss how best to pool their limited resources to respond to mpox.