Before Israeli strikes on Friday, Washington and Tehran had held several rounds of talks on Iran's nuclear program, as concerns mounted about its rapid expansion.
Iran has significantly ramped up its nuclear program in recent years, after a landmark deal with world powers curbing its nuclear activities in exchange for sanction relief began to unravel in 2018 when the United States unilaterally withdrew, said AFP.
As of mid-May, Iran's total enriched uranium stockpile was estimated at 9,247.6 kilograms -- or more than 45 times the limit set out in the 2015 deal -- according to the latest report by the International Atomic Energy Agency (IAEA).
Among its stockpiles, Iran has an estimated 408.6 kilograms enriched to up to 60 percent -- just a short step from the 90 percent needed for a nuclear warhead.
The country now theoretically has enough near-weapons-grade material, if further refined, for about 10 nuclear bombs, according to the definition by the Vienna-based IAEA.
But Iran has always denied any ambition to develop nuclear weapons.
Below is a list of Iran's key nuclear sites, which are subject to regular inspections by the UN nuclear watchdog:
Uranium enrichment plants
Natanz
About 250 kilometers (150 miles) south of Tehran, Natanz is Iran's heavily bunkered main uranium enrichment site, whose existence was first revealed in 2002.
Natanz operates nearly 70 cascades of centrifuges at its two enrichment plants, one of which is underground. A cascade is a series of centrifuges -- machines used in the process of enriching uranium.
In April 2021, the site was damaged in an attack that Iran said was an act of sabotage by Israel.
On Friday, Israel's operation struck at the "heart of Iran's nuclear enrichment program", targeting the atomic facility in Natanz and nuclear scientists, Israeli Prime Minister Benjamin Netanyahu said.
IAEA head Rafael Grossi confirmed the Natanz site was "among targets".
Fordo
Secretly built in violation of United Nations resolutions under a mountain near the holy central city of Qom, Fordo was first publicly revealed in 2009.
Initially described as an "emergency" facility built underground to protect it from potential air attacks, Iran later indicated it was an enrichment plant capable of housing about 3,000 centrifuges.
In 2023, uranium particles enriched up to 83.7 percent were discovered at the Fordo plant, which Iran claimed were the product of "unintended fluctuations" during the enrichment process.
Uranium conversion and research reactors
Isfahan
At the uranium conversion facility at Isfahan in central Iran, raw mined uranium is processed into uranium tetrafluoride (UF4) and then into uranium hexafluoride (UF6), a feed gas for centrifuges.
The plant was industrially tested in 2004 upon its completion.
The Isfahan center also harbors a nuclear fuel fabrication facility, which was inaugurated in 2009 and produces low-enriched fuel for use in power plants.
In July 2022, Iran announced plans to construct a new research reactor there.
Arak
Work on the Arak heavy-water research reactor on the outskirts of the village of Khondab began in the 2000s, but was halted under the terms of the 2015 deal.
Iran has meanwhile informed the IAEA about its plans to commission the reactor by 2026.
The research reactor was officially intended to produce plutonium for medical research and the site includes a production plant for heavy water.
Tehran
The Tehran nuclear research center houses a reactor that was supplied by the United States in 1967 for the production of medical radioisotopes.
Nuclear power plant
Bushehr
Iran's only nuclear power plant in the southern port city of Bushehr was built by Russia and began operating at a lower capacity in 2011 before being plugged into the national power grid in 2012.
Russia continues to deliver nuclear fuel for the plant, which remains under IAEA control.
A German company began construction on the plant with a 1,000-megawatt nominal capacity until the project was halted in the wake of the 1979 Iranian revolution. Moscow later completed it.
Darkhovin and Sirik
Iran began construction in late 2022 on a 300-megawatt power plant in Darkhovin, in the country's southwest. In early 2024, it also began work in Sirik, in the Strait of Hormuz, on a new complex of four individual plants with a combined capacity of 5,000 megawatts.
