An Israeli strike targeted a residential building in the Mezzah suburb west of the Syrian capital Damascus, Syria's state news agency reported on Tuesday.
Preliminary reports indicated that the strike had resulted in injuries among civilians, Syrian state media reported.
State media earlier reported that Syria's air defenses had intercepted "hostile" targets in the vicinity of Damascus.
Israel has been carrying out strikes against Iran-linked targets in Syria for years but has ramped up such raids since last year's Oct. 7 attack by Palestinian group Hamas on Israeli territory that sparked the Gaza war.