Does Human Growth Hormone Slow the Aging Process?

Does Human Growth Hormone Slow the Aging Process?
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Does Human Growth Hormone Slow the Aging Process?

Does Human Growth Hormone Slow the Aging Process?

Q. I haven't heard much about human growth hormone lately. Is there any new evidence to support its use in helping older men?

A. The pituitary gland in the brain makes and secretes natural growth hormone. In combination with other hormones, such as IGF-1 (insulin growth factor 1), it is responsible for body development early in life.

Throughout your life, growth hormone continues to play a role in protein production and helps the body use fat for energy. Children deficient in growth hormone do not grow to their full potential height and have short stature. The FDA approved a synthetic human growth hormone (HGH) as a replacement in these children, which helps them grow taller.

In the early 1980s, synthetic HGH became a popular but illegal performance-enhancing drug. The hype around HGH and superior athletic performance has always been greater than the reality. In fact, multiple clinical trials comparing HGH to a placebo have never shown an athletic advantage for people who use it.

As we age, the amount of growth hormone secreted by our pituitary gland naturally declines. By age 55, blood levels of growth hormone are about one-third lower than they are in people ages 18 to 35. This drop also coincides with the reduced muscle mass and increased body fat that happens with aging.

It's easy to see why HGH was touted as an "anti-aging" supplement. But does it make you feel and look 10 years younger, as some would suggest? We do know that healthy adults who take HGH can increase muscle by about 6% and reduce body fat by about the same amount. Strength also improves in some muscle groups, but not in all.

But there are downsides to using HGH. It can cause insulin to be less effective, which can raise blood sugar levels and increase the risk of diabetes. HGH also can lead to joint and muscle pain, breast enlargement, fluid retention, high blood pressure, and carpal tunnel syndrome. And then there is this: animal studies suggest that lower levels of growth hormone activity may lead to longer life. So, theoretically, HGH injections might actually shorten life span, challenging the notion that HGH is anti-aging.

The FDA has approved HGH in adults only for a few uncommon conditions, such as documented growth hormone deficiency. Synthetic human growth hormone is a prescription drug and cannot be obtained legally without a doctor's approval. To have any effect, it must be injected. Don't waste your money on pills containing HGH. The active ingredient is not absorbed when taken by mouth.

You can slow the tick of the clock with the time-tested formula of eating a healthy diet with enough protein and pursuing a regular program of aerobic and resistance exercise. This approach is better than any drug for enhancing your vigor and enjoyment of life.

by Howard LeWine, M.D.
Editor in Chief, Harvard Men's Health Watch



Vietnam Scraps Two-Child Limit as Birth Rate Declines 

A grandfather talks to his grandchild inside a kindergarten in Hanoi on June 4, 2025. (AFP)
A grandfather talks to his grandchild inside a kindergarten in Hanoi on June 4, 2025. (AFP)
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Vietnam Scraps Two-Child Limit as Birth Rate Declines 

A grandfather talks to his grandchild inside a kindergarten in Hanoi on June 4, 2025. (AFP)
A grandfather talks to his grandchild inside a kindergarten in Hanoi on June 4, 2025. (AFP)

Vietnam's communist government has scrapped its long-standing policy of limiting families to two children, state media said Wednesday, as the country battles to reverse a declining birth rate.

The country banned couples from having more than two children in 1988, but a family's size is now a decision for each individual couple, Vietnam News Agency said.

The country has experienced historically low birth rates in the last three years. The total fertility rate dropped to 1.91 children per woman in 2024, below replacement level, the ministry of health said this year.

Birth rates have fallen from 2.11 children per woman in 2021, to 2.01 in 2022 and 1.96 in 2023.

This trend is most pronounced in urbanized, economically developed regions, especially in big cities such as Hanoi and Ho Chi Minh City as the cost of living rises.

Tran Minh Huong, a 22-year-old office worker, told AFP that the government regulation mattered little to her as she had no plans to have children.

"Even though I am an Asian, with social norms that say women need to get married and have kids, it's too costly to raise a child."

Deputy Health Minister Nguyen Thi Lien Huong, speaking at a conference earlier this year, warned it was increasingly difficult to encourage families to have more children, despite policy adjustments and public campaigns.

She emphasized that the declining birth rate poses challenges to long-term socio-economic development, including an aging population and workforce shortages.

She urged society to shift its mindset from focusing solely on family planning to a broader perspective of population and development.

Vietnam is also grappling with sex imbalances due to a historic preference for boys. On Tuesday the ministry of health proposed tripling the current fine to $3,800 "to curb fetal gender selection", according to state media.

It is forbidden to inform parents of the sex of their baby before birth in Vietnam, as well as to perform an abortion for sex-selection reasons, with penalties imposed on clinics who break the law.

The sex ratio at birth, though improved, remains skewed at 112 boys for every 100 girls.

Hoang Thi Oanh, 45, has three children but received fewer benefits after the birth of her youngest, due to the two-child policy.

"It's good that at last the authorities removed this ban," she said, but added that "raising more than two kids nowadays is too hard and costly."

"Only brave couples and those better-off would do so. I think the authorities will even have to give bonuses to encourage people to have more than two children."

Vietnam's neighbor China ended its own strict "one-child policy", imposed in the 1980s due to fears of overpopulation, in 2016 and in 2021 permitted couples to have three children.

But as in many countries, the soaring cost of living has proved a drag on birth rates and the moves have failed to reverse China's demographic decline -- its population fell for the third year in a row in 2024.