BioNTech Produces 10 Times More Antibodies than China's Sinovac: Study

Pfizer said an early peek at its vaccine data suggests the shots may be 90% effective at preventing COVID-19. (Reuters)
Pfizer said an early peek at its vaccine data suggests the shots may be 90% effective at preventing COVID-19. (Reuters)
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BioNTech Produces 10 Times More Antibodies than China's Sinovac: Study

Pfizer said an early peek at its vaccine data suggests the shots may be 90% effective at preventing COVID-19. (Reuters)
Pfizer said an early peek at its vaccine data suggests the shots may be 90% effective at preventing COVID-19. (Reuters)

People who received BioNTech's coronavirus vaccine had ten times the amount of antibodies than those given China's Sinovac, a Hong Kong study has shown, adding to growing data on different jabs' effectiveness.

The University of Hong Kong (HKU) research, based on a study of 1,442 healthcare workers, was published in Lancet Microbe on Thursday.

Researchers said antibodies are not the only measure of a vaccine's success at fighting a particular disease.

But they warned that "the difference in concentrations of neutralizing antibodies identified in our study could translate into substantial differences in vaccine effectiveness".

Those who received Sinovac had "similar or lower" levels of antibodies to those seen in patients who caught and successfully fought off the disease.

The study adds to the growing body of evidence that vaccines using pioneering mRNA technology -- such as BioNTech and Moderna -- offer better protection against the coronavirus and its variants that those developed by more traditional methods such as using inactivated virus parts.

Traditional vaccines are cheaper to produce and less complicated to transport and store, making them a vital tool for fighting the pandemic in less wealthy countries.

- 'Many lives still saved' -
Epidemiologist Ben Cowling, one of the report's authors, said people should still get vaccinated with Sinovac if there was no other option because some protection was always better than none.

"Don't let the perfect be the enemy of the good," he told AFP.

"It is clearly better to go and get vaccinated with an inactivated vaccine than to wait and not get vaccinated," he added.

"Many, many lives have been saved by the inactivated vaccine."

The researchers said their data suggested "alternative strategies" such as earlier booster shots might be needed to increase protection for those who have received Sinovac.

Cowling said when to give booster shots would be the next phase of their ongoing studies.

"The priority would be boosters for people who received Sinovac while boosters for people who initially received BioNTech might not be so urgent," he said.

- Politics -
Hong Kong has been a world leader in studying coronaviruses ever since a SARS outbreak which began in southern China swept through the city in 2003.

The city currently offers both German-made BioNTech shots and Sinovac.

Despite ample supplies, take-up has been slow, with only 28 percent of the city's 7.5 million residents fully vaccinated with two shots.

So far some 2.6 million BioNTech doses have been administered compared to 1.8 million Sinovac shots.

The rollout has been caught up in Hong Kong's febrile politics, as China cracks down on dissent in the city in response to huge and often violent democracy protests two years ago.

At the start of the vaccination campaign Hong Kong's pro-Beijing leaders very visibly and near unanimously opted for Sinovac.

One doctor's clinic that recommended BioNTech over Sinovac was kicked out of the city's vaccination program.

Many of the city's leading epidemiologists have gone with BioNTech, and said publicly that it is their preferred shot.



Australian Man Dies from Bat Bite

Fruit bats are known to carry Australian bat lyssavirus, but it is not known what species delivered the fatal bite. JOHN WILSON / AFP/File
Fruit bats are known to carry Australian bat lyssavirus, but it is not known what species delivered the fatal bite. JOHN WILSON / AFP/File
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Australian Man Dies from Bat Bite

Fruit bats are known to carry Australian bat lyssavirus, but it is not known what species delivered the fatal bite. JOHN WILSON / AFP/File
Fruit bats are known to carry Australian bat lyssavirus, but it is not known what species delivered the fatal bite. JOHN WILSON / AFP/File

An Australian man has died from an "extremely rare" rabies-like infection transmitted by a bat bite, health officials said Thursday.

The man in his 50s was bitten by a bat carrying Australian bat lyssavirus several months ago, the health service in New South Wales said.

"We express our sincere condolences to the man's family and friends for their tragic loss," NSW Health said in a statement.

"While it is extremely rare to see a case of Australian bat lyssavirus, there is no effective treatment for it."

The man from northern New South Wales, who has not been identified, was this week listed as being in a "critical condition" in hospital, said AFP.

The virus -- a close relative to rabies, which does not exist in Australia -- is transmitted when bat saliva enters the human body through a bite or scratch.

First symptoms can take days or years to appear.

Early signs of the disease are flu-like -- a headache, fever and fatigue, the health service said.

The victim's condition rapidly deteriorates, leading to paralysis, delirium, convulsions and death.

There were only three previous cases of human infection by Australian bat lyssavirus since it was first identified in 1996 -- all of them fatal.

People should avoid touching or handling bats, as any bat in Australia could carry lyssavirus, the New South Wales health service said.

"If you or someone you know is bitten or scratched by a bat, you need to wash the wound thoroughly for 15 minutes right away with soap and water and apply an antiseptic with anti-virus action," it said.

"Patients then require treatment with rabies immunoglobulin and rabies vaccine."

The virus has been found in species of flying foxes and insect-eating microbats, NSW Health said.

The type of bat involved in the latest fatality has not been identified.