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BioNTech Produces 10 Times More Antibodies than China's Sinovac: Study

Pfizer said an early peek at its vaccine data suggests the shots may be 90% effective at preventing COVID-19. (Reuters)
Pfizer said an early peek at its vaccine data suggests the shots may be 90% effective at preventing COVID-19. (Reuters)
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BioNTech Produces 10 Times More Antibodies than China's Sinovac: Study

Pfizer said an early peek at its vaccine data suggests the shots may be 90% effective at preventing COVID-19. (Reuters)
Pfizer said an early peek at its vaccine data suggests the shots may be 90% effective at preventing COVID-19. (Reuters)

People who received BioNTech's coronavirus vaccine had ten times the amount of antibodies than those given China's Sinovac, a Hong Kong study has shown, adding to growing data on different jabs' effectiveness.

The University of Hong Kong (HKU) research, based on a study of 1,442 healthcare workers, was published in Lancet Microbe on Thursday.

Researchers said antibodies are not the only measure of a vaccine's success at fighting a particular disease.

But they warned that "the difference in concentrations of neutralizing antibodies identified in our study could translate into substantial differences in vaccine effectiveness".

Those who received Sinovac had "similar or lower" levels of antibodies to those seen in patients who caught and successfully fought off the disease.

The study adds to the growing body of evidence that vaccines using pioneering mRNA technology -- such as BioNTech and Moderna -- offer better protection against the coronavirus and its variants that those developed by more traditional methods such as using inactivated virus parts.

Traditional vaccines are cheaper to produce and less complicated to transport and store, making them a vital tool for fighting the pandemic in less wealthy countries.

- 'Many lives still saved' -
Epidemiologist Ben Cowling, one of the report's authors, said people should still get vaccinated with Sinovac if there was no other option because some protection was always better than none.

"Don't let the perfect be the enemy of the good," he told AFP.

"It is clearly better to go and get vaccinated with an inactivated vaccine than to wait and not get vaccinated," he added.

"Many, many lives have been saved by the inactivated vaccine."

The researchers said their data suggested "alternative strategies" such as earlier booster shots might be needed to increase protection for those who have received Sinovac.

Cowling said when to give booster shots would be the next phase of their ongoing studies.

"The priority would be boosters for people who received Sinovac while boosters for people who initially received BioNTech might not be so urgent," he said.

- Politics -
Hong Kong has been a world leader in studying coronaviruses ever since a SARS outbreak which began in southern China swept through the city in 2003.

The city currently offers both German-made BioNTech shots and Sinovac.

Despite ample supplies, take-up has been slow, with only 28 percent of the city's 7.5 million residents fully vaccinated with two shots.

So far some 2.6 million BioNTech doses have been administered compared to 1.8 million Sinovac shots.

The rollout has been caught up in Hong Kong's febrile politics, as China cracks down on dissent in the city in response to huge and often violent democracy protests two years ago.

At the start of the vaccination campaign Hong Kong's pro-Beijing leaders very visibly and near unanimously opted for Sinovac.

One doctor's clinic that recommended BioNTech over Sinovac was kicked out of the city's vaccination program.

Many of the city's leading epidemiologists have gone with BioNTech, and said publicly that it is their preferred shot.

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Varieties

Coffee Regions Hit by Extra Days of Extreme Heat, Say Scientists 

17 April 2012, North Rhine-Westphalia, Vluyn: A general view of Arabica Coffee beans. (dpa)
17 April 2012, North Rhine-Westphalia, Vluyn: A general view of Arabica Coffee beans. (dpa)
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Coffee Regions Hit by Extra Days of Extreme Heat, Say Scientists 

17 April 2012, North Rhine-Westphalia, Vluyn: A general view of Arabica Coffee beans. (dpa)
17 April 2012, North Rhine-Westphalia, Vluyn: A general view of Arabica Coffee beans. (dpa)

The world's main coffee-growing regions are roasting under additional days of climate change-driven heat every year, threatening harvests and contributing to higher prices, researchers said Wednesday.

An analysis found that there were 47 extra days of harmful heat per year on average in 25 countries representing nearly all global coffee production between 2021 and 2025, according to independent research group Climate Central.

Brazil, Vietnam, Colombia, Ethiopia and Indonesia -- which supply 75 percent of the world's coffee -- experienced on average 57 additional days of temperatures exceeding the threshold of 30C.

"Climate change is coming for our coffee. Nearly every major coffee-producing country is now experiencing more days of extreme heat that can harm coffee plants, reduce yields, and affect quality," said Kristina Dahl, Climate Central's vice president for science.

"In time, these impacts may ripple outward from farms to consumers, right into the quality and cost of your daily brew," Dahl said in a statement.

US tariffs on imports from Brazil, which supplies a third of coffee consumed in the United States, contributed to higher prices this past year, Climate Central said.

But extreme weather in the world's coffee-growing regions is "at least partly to blame" for the recent surge in prices, it added.

Coffee cultivation needs optimal temperatures and rainfall to thrive.

Temperatures above 30C are "extremely harmful" to arabica coffee plants and "suboptimal" for the robusta variety, Climate Central said. Those two plant species produce the majority of the global coffee supply.

For its analysis, Climate Central estimated how many days each year would have stayed below 30C in a world without carbon pollution but instead exceeded that level in reality -- revealing the number of hot days added by climate change.

The last three years have been the hottest on record, according to climate monitors.

Varieties

Dog Gives Olympics Organizers Paws for Thought

A dog wanders on the ski trail during the women's team cross country free sprint qualification event of the Milano Cortina 2026 Winter Olympic Games at Tesero Cross-Country Skiing Stadium in Lago di Tesero (Val di Fiemme), on February 18, 2026. (Photo by Anne-Christine POUJOULAT / AFP)
A dog wanders on the ski trail during the women's team cross country free sprint qualification event of the Milano Cortina 2026 Winter Olympic Games at Tesero Cross-Country Skiing Stadium in Lago di Tesero (Val di Fiemme), on February 18, 2026. (Photo by Anne-Christine POUJOULAT / AFP)
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Dog Gives Olympics Organizers Paws for Thought

A dog wanders on the ski trail during the women's team cross country free sprint qualification event of the Milano Cortina 2026 Winter Olympic Games at Tesero Cross-Country Skiing Stadium in Lago di Tesero (Val di Fiemme), on February 18, 2026. (Photo by Anne-Christine POUJOULAT / AFP)
A dog wanders on the ski trail during the women's team cross country free sprint qualification event of the Milano Cortina 2026 Winter Olympic Games at Tesero Cross-Country Skiing Stadium in Lago di Tesero (Val di Fiemme), on February 18, 2026. (Photo by Anne-Christine POUJOULAT / AFP)

A dog decided he would bid for an unlikely Olympic medal on Wednesday as he joined the women's cross country team free sprint in the Milan-Cortina Games.

The dog ran onto the piste in Tesero in northern Italy and gamely, even without skis, ran behind two of the competitors, Greece's Konstantina Charalampidou and Tena Hadzic of Croatia.

He crossed the finishing line, his moment of glory curtailed as he was collared by the organizers and led away -- his owner no doubt will have a bone to pick with him when they are reunited.

Varieties

Olives, Opera and a Climate-Neutral Goal: How a Mural in Greece Won ‘Best in the World’ 

A building with the mural entitled “Kalamata” depicting opera legend Maria Callas by artist Kleomenis Kostopoulos is seen in Kalamata town, about 240 kilometers (150 miles) southwest of Athens, Monday, Feb. 9, 2026. (AP) 
A building with the mural entitled “Kalamata” depicting opera legend Maria Callas by artist Kleomenis Kostopoulos is seen in Kalamata town, about 240 kilometers (150 miles) southwest of Athens, Monday, Feb. 9, 2026. (AP) 
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Olives, Opera and a Climate-Neutral Goal: How a Mural in Greece Won ‘Best in the World’ 

A building with the mural entitled “Kalamata” depicting opera legend Maria Callas by artist Kleomenis Kostopoulos is seen in Kalamata town, about 240 kilometers (150 miles) southwest of Athens, Monday, Feb. 9, 2026. (AP) 
A building with the mural entitled “Kalamata” depicting opera legend Maria Callas by artist Kleomenis Kostopoulos is seen in Kalamata town, about 240 kilometers (150 miles) southwest of Athens, Monday, Feb. 9, 2026. (AP) 

Long known for its olives and seaside charm, the southern Greek city of Kalamata has found itself in the spotlight thanks to a towering mural that reimagines legendary soprano Maria Callas as an allegory for the city itself.

The massive artwork on the side of a prominent building in the city center has been named 2025’s “Best Mural of the World” by Street Art Cities, a global platform celebrating street art.

Residents of Kalamata, approximately 240 kilometers (150 miles) southwest of Athens, cultivate the world-renowned olives, figs and grapes that feature prominently on the mural.

That was precisely the point.

Vassilis Papaefstathiou, deputy mayor of strategic planning and climate neutrality, explained Kalamata is one of the few Greek cities with the ambitious goal of becoming climate-neutral by 2030. He and other city leaders wanted a way to make abstract concepts, including sustainable development, agri-food initiatives, and local economic growth, more tangible for the city’s nearly 73,000 residents.

That’s how the idea of a massive mural in a public space was born.

“We wanted it to reflect a very clear and distinct message of what sustainable development means for a regional city such as Kalamata,” Papaefstathiou said. “We wanted to create an image that combines the humble products of the land, such as olives and olive oil — which, let’s be honest, are famous all over the world and have put Kalamata on the map — with the high-level art.”

“By bringing together what is very elevated with ... the humbleness of the land, our aim was to empower the people and, in doing so, strengthen their identity. We want them to be proud to be Kalamatians.”

Southern Greece has faced heatwaves, droughts and wildfires in recent years, all of which affect the olive groves on which the region’s economy is hugely dependent.

The image chosen to represent the city was Maria Callas, widely hailed as one of the greatest opera singers of the 20th century and revered in Greece as a national cultural symbol. She may have been born in New York to Greek immigrant parents, but her father came from a village south of Kalamata. For locals, she is one of their own.

This connection is also reflected in practice: the alumni association at Kalamata’s music school is named for Callas, and the cultural center houses an exhibition dedicated to her, which includes letters from her personal archive.

Artist Kleomenis Kostopoulos, 52, said the mural “is not actually called ‘Maria Callas,’ but ‘Kalamata’ and my attempt was to paint Kalamata (the city) allegorically.”

Rather than portraying a stylized image of the diva, Kostopoulos said he aimed for a more grounded and human depiction. He incorporated elements that connect the people to their land: tree branches — which he considers the above-ground extension of roots — birds native to the area, and the well-known agricultural products.

“The dress I create on Maria Callas in ‘Kalamata’ is essentially all of this, all of this bloom, all of this fruition,” he said. “The blessed land that Kalamata itself has ... is where all of these elements of nature come from.”

Creating the mural was no small feat. Kostopoulos said it took around two weeks of actual work spread over a month due to bad weather. He primarily used brushes but also incorporated spray paint and a cherry-picker to reach all edges of the massive wall.

Papaefstathiou, the deputy mayor, said the mural has become a focal point.

“We believe this mural has helped us significantly in many ways, including in strengthening the city’s promotion as a tourist destination,” he said.

Beyond tourism, the mural has sparked conversations about art in public spaces. More building owners in Kalamata have already expressed interest in hosting murals.

“All of us — residents, and I personally — feel immense pride,” said tourism educator Dimitra Kourmouli.

Kostopoulos said he hopes the award will have a wider impact on the art community and make public art more visible in Greece.

“We see that such modern interventions in public space bring tremendous cultural, social, educational and economic benefits to a place,” he said. “These are good springboards to start nice conversations that I hope someday will happen in our country, as well.”