Could the Omicron Variant Bring Milder Illness?

Syringes with needles are seen in front of a displayed stock graph and words "Omicron SARS-CoV-2" in this illustration taken, November 27, 2021. (Reuters)
Syringes with needles are seen in front of a displayed stock graph and words "Omicron SARS-CoV-2" in this illustration taken, November 27, 2021. (Reuters)
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Could the Omicron Variant Bring Milder Illness?

Syringes with needles are seen in front of a displayed stock graph and words "Omicron SARS-CoV-2" in this illustration taken, November 27, 2021. (Reuters)
Syringes with needles are seen in front of a displayed stock graph and words "Omicron SARS-CoV-2" in this illustration taken, November 27, 2021. (Reuters)

The Omicron variant, spreading now in southern Africa and detected in over 30 other countries, has prompted fears it could significantly undermine the effectiveness of vaccines against COVID-19.

Yet as scientists race to understand the full consequences of Omicron, some are also asking whether this new version of coronavirus might cause milder illness than its predecessors. While they caution that it is far too early to draw conclusions, here is what is known so far:

What do the data show?

Evidence from initial cases of the new variant is limited.

Among 70 cases reported in Europe that included information on disease severity, half of the patients had no symptoms and half had mild symptoms, according to a report on Thursday by the European Center for Disease Prevention and Control.

There were no cases of severe disease, hospitalization, or death. However, the European agency said it would require data on hundreds of cases to accurately assess disease complications, estimating that could take several weeks. In addition, most cases detected in Europe so far have been in younger people who were fully vaccinated, making them less likely to suffer severe illness.

In South Africa, where the daily number of reported COVID-19 cases doubled on Wednesday to 8,561, symptoms for reinfected patients and those infected after vaccination appear to be mild.

"Some evidence from South Africa suggests that it may actually cause more mild illness but ... I caution you that a lot of the patients South Africa initially were among young university students," Dr. Carlos Del Rio, an infectious diseases expert at Emory University in Atlanta, said on Thursday during an online briefing from the Infectious Diseases Society of America.

Is omicron a ‘less fit’ version of coronavirus?

While data on real world infections continues to emerge, scientists are conducting laboratory studies to decipher Omicron. The variant has about 50 mutations not seen in combination before, including more than 30 mutations on the spike protein the coronavirus uses to attach to human cells. Vaccines in current use target that spike protein.

"Typically when viruses accumulate a lot of mutations they lose some fitness," said Dr. John Wherry, director of the Penn Institute for Immunology in Philadelphia. Certain Omicron mutations may impair the ability of the virus to cleave, changing the behavior of the spike protein, he said.

Some scientists have theorized Omicron may have developed over a period of months in an immunocompromised individual, such as an HIV patient in southern Africa. If so, "the virus adapted not to kill that host," Wherry said.

There are competing theories that the latest variant evolved from an animal host.

Will omicron become the dominant variant?

The other central question surrounding Omicron is whether it will overtake the Delta variant, which still accounts for the overwhelming majority of known infections worldwide. If Omicron does become dominant, but causes milder illness, it could mark a turning point toward the virus eventually becoming a seasonal threat, like influenza, said Sumit Chanda, an infectious disease researcher at the Scripps Research Department of Immunology and Microbiology in San Diego.

The European Union's public health agency said on Thursday the Omicron variant could be responsible for more than half of all COVID-19 infections in Europe within a few months.

While the research into Omicron is underway, disease experts say people must remain vigilant against the coronavirus by getting either initial vaccinations or booster shots, as well as wearing masks in indoor or crowded settings, ventilating rooms and washing hands.



Sidelined by Trump, Macron Tries to Rally Europe on Ukraine. But Divisions Run Deep

French President Emmanuel Macron welcomes Germany's Chancellor Olaf Scholz before an informal summit of European leaders to discuss the situation in Ukraine and European security at the Élysée Presidential Palace in Paris on February 17, 2025. (AFP)
French President Emmanuel Macron welcomes Germany's Chancellor Olaf Scholz before an informal summit of European leaders to discuss the situation in Ukraine and European security at the Élysée Presidential Palace in Paris on February 17, 2025. (AFP)
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Sidelined by Trump, Macron Tries to Rally Europe on Ukraine. But Divisions Run Deep

French President Emmanuel Macron welcomes Germany's Chancellor Olaf Scholz before an informal summit of European leaders to discuss the situation in Ukraine and European security at the Élysée Presidential Palace in Paris on February 17, 2025. (AFP)
French President Emmanuel Macron welcomes Germany's Chancellor Olaf Scholz before an informal summit of European leaders to discuss the situation in Ukraine and European security at the Élysée Presidential Palace in Paris on February 17, 2025. (AFP)

French President Emmanuel Macron painted a veneer of European unity by inviting a small number of handpicked European leaders to the Élysée Palace, while the Trump administration sidelined the continent by moving ahead with direct negotiations on Tuesday with Russia on the war in Ukraine. But beneath the diplomatic pageantry, cracks in European consensus were hard to ignore.

One question loomed: Could Europe take charge of its own security, or would it remain reactive to US and Russian decisions?

From Macron’s push for European-led defense to Keir Starmer’s “third way” diplomacy, Giorgia Meloni’s balancing act between Brussels and Washington, and Olaf Scholz’s resistance to breaking with NATO, Europe remains divided on its next move.

France – Macron seeks to take the lead

By hosting the Monday summit in his Parisian palace, Macron reinforced his image of the imperial French “Sun King” and his bid to become the dominant voice on Ukraine and European security. With Germany’s Scholz politically weakened, the UK outside the EU, and Italy leaning toward Trump, Macron has emerged as the bloc’s most vocal advocate for strategic autonomy.

With a presidential mandate until 2027 and France’s nuclear arsenal making it Europe’s only atomic power, Macron has positioned himself as the only leader with both the ambition and authority to act. His proposal for a European-led security force in Ukraine, even in a limited training and logistics role, fits into his broader push for a continent less dependent on Washington.

But forging consensus is proving difficult: Germany is resisting, key frontline EU nations were left out of the summit, and Trump’s unpredictability clouds Europe’s security outlook.

“Since his first term, Macron has sought to impose himself as Europe’s strongman,” said French political analyst Jean-Yves Camus. “He has always presented himself as the natural leader of liberals against nationalist populists. One cannot say that this has worked well.”

While Macron is setting the stage, the question remains: Is Europe ready to follow?

United Kingdom – Starmer’s ‘third way’ strategy

Keir Starmer is charting a different course, positioning himself as Europe’s key link to Washington — while maintaining a firm pro-Ukraine stance.

Having met Trump before the election —“I like him a lot,” the US president said — the British prime minister is set to travel to Washington next week in what some see as an effort to bridge the US-Europe divide, and a hallmark of the “special relationship.”

While Trump moves toward de-escalation in Ukraine, Starmer is doubling down on support for Kyiv, stating the UK is “ready and willing” to send British troops if necessary. This stance stands in contrast to Macron and Scholz’s more cautious approach.

Starmer’s surprising decision not to sign a key international declaration on the future of AI last week — aligning with the US rather than the EU — has raised questions about whether Britain is shifting closer to Washington on broader geopolitical issues.

“The UK is unique in that it’s practically the only major ally that Trump hasn’t purposefully antagonized since his inauguration,” said Anand Sundar, a special advisor at the European Council on Foreign Relations. “The Starmer government is doing everything it can to not put a target on its back.”

Some analysts suggest Starmer is positioning himself as Trump’s European “whisperer,” able to influence the White House while staying in step with Europe.

Italy – Meloni’s balancing act

Giorgia Meloni, the only leader of a major European economy to attend Trump’s inauguration in January, arrived late to the Paris summit and left without making a public statement - moves observers saw as signs of skepticism toward the meeting.

According to Italian news agency ANSA, Meloni questioned why the summit was held in Paris rather than Brussels, the EU’s natural decision-making hub, and criticized the exclusion of frontline states such as the Baltic nations, Sweden, and Finland.

At the summit, she pushed back against deploying European troops to Ukraine, calling it “the most complex and least effective option” - especially without firm security guarantees for Kyiv.

Observers noted that Meloni echoed some of US Vice President JD Vance’s criticism of Europe’s reliance on US protection. “We shouldn’t be asking what the Americans can do for us, but what we must do for ourselves,” she said, according to ANSA.

Despite her skepticism, Meloni still engaged in the talks, bringing Italy’s concerns over long-term European military commitments to the table.

Hungary – Orban’s absence

Notably absent from the Paris talks was Hungarian Prime Minister Viktor Orbán, a close Trump ally and frequent critic of EU policies.

While no official reason was given for his exclusion, some observers saw it as a pointed message from Paris and its European allies about the limits of engagement with leaders seen as too closely aligned with Trump’s worldview.

Germany – Scholz’s irritation

If Macron is stepping forward, Scholz is pushing back.

At the summit, the German Chancellor rejected Macron’s proposal for a European-led security force in Ukraine, calling it “completely premature” and “highly inappropriate” given the ongoing war.

Scholz didn’t hide his frustration, saying he was “a little irritated” that peacekeeping forces were even being discussed “at the wrong time.” He insisted NATO—not an independent European force—must remain the foundation of security.

Due to its historical legacy from the world wars, some argue that Germany has always been willing to cede European security leadership to France, a role the French have pursued since President Charle de Gaulle.

At the same time, the debate over military spending is intensifying, as NATO officials stress the alliance’s 2% GDP target is now a baseline rather than a cap.