Study: AstraZeneca Vaccine Booster Works Against Omicron

People pose with syringe with needle in front of displayed AstraZeneca logo in this illustration taken, December 11, 2021. REUTERS/Dado Ruvic/Illustration
People pose with syringe with needle in front of displayed AstraZeneca logo in this illustration taken, December 11, 2021. REUTERS/Dado Ruvic/Illustration
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Study: AstraZeneca Vaccine Booster Works Against Omicron

People pose with syringe with needle in front of displayed AstraZeneca logo in this illustration taken, December 11, 2021. REUTERS/Dado Ruvic/Illustration
People pose with syringe with needle in front of displayed AstraZeneca logo in this illustration taken, December 11, 2021. REUTERS/Dado Ruvic/Illustration

A three-dose course of AstraZeneca's COVID-19 vaccine is effective against the rapidly-spreading Omicron coronavirus variant, the pharmaceutical company said on Thursday, citing data from an Oxford University lab.

Findings from the study, yet to be published in a peer-reviewed medical journal, match those from rivals Pfizer-BioNTech and Moderna which have also found a third dose of their shots works against Omicron, Reuters reported.

The study on AstraZeneca's vaccine, Vaxzevria, showed that after a three-dose course of the vaccine, neutralizing levels against Omicron were broadly similar to those against the virus's Delta variant after two doses.

The London-listed company said researchers at Oxford University who carried out the study were independent from those who worked on the vaccine with AstraZeneca.

"As we better understand Omicron, we believe we will find that T-cell response provides durable protection against severe disease and hospitalizations," Mene Pangalos, the head of AstraZeneca's biopharmaceuticals R&D said, referring to a critical component of the immune system that respond to fight infection.

Antibody levels against Omicron after the booster shot were higher than antibodies in people who had been infected with and recovered naturally from COVID-19, the Anglo-Swedish drugmaker added.

Although the early data is positive for the company, AstraZeneca said on Tuesday it was working with its partner Oxford University to produce a vaccine tailored for Omicron, joining similar efforts from other vaccine-makers.

The Oxford study analyzed blood samples from those infected with COVID-19, those vaccinated with two doses and a booster, and those previously infected with other variants of concern. It included samples from 41 people given three doses of Vaxzevria.

Scientists and governments are scrambling to bolster defenses against Omicron with shots and therapies, as the variant threatens to become dominant globally and has prompted renewed curbs ahead of the holidays to contain infections.

Britain earlier this month backed the use of boosters after it found that a third dose significantly restored protection against mild disease caused by Omicron, in part reversing an otherwise steep drop in vaccine effectiveness.



Iran Says 5 Inmates at Evin Prison Were Killed in Israel's Airstrike on Tehran

Evin Prison (File photo: Reuters)
Evin Prison (File photo: Reuters)
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Iran Says 5 Inmates at Evin Prison Were Killed in Israel's Airstrike on Tehran

Evin Prison (File photo: Reuters)
Evin Prison (File photo: Reuters)

An Israeli airstrike on Iran's capital last month killed five inmates at Evin prison and resulted in the escape of several others, Iranian media reported Saturday.

The semi-official ILNA news agency and other Iranian media quoted a spokesman for Iran’s judiciary that the five inmates killed in the June 23 strike had been convicted on financial offences. The spokesman didn't name the victims or give any further details.

The judiciary’s own news website, Mizanonline quoted spokesman Asghar Jahangir as saying only that “small number" of inmates were killed. He added that an “insignificant number of inmates” had also escaped and that authorities would soon bring them back into custody, AFP reported.

Jahangir said no one serving time at Evin prison for working with Israel's spy agency Mossad was injured in the attack.

Iranian authorities last month put the death toll from the airstrike at 71. But Iranian media later raised that number to 80 including staff, soldiers, inmates and visiting family members.

It's unclear why Israel targeted the prison. The Israeli Defense Ministry had said on the day of the airstrikes that 50 aircraft dropped 100 munitions on military targets “based on high-quality and accurate intelligence from the Intelligence Branch.”

The New York-based Center for Human Rights had criticized Israel for striking the prison - seen as a symbol of repression of any opposition - saying it violated the principle of distinction between civilian and military targets.

The 12-day air war left more than 1,060 dead in Iran and 28 dead in Israel.