عربي English Türkçe اردو فارسى
Logo
Latest News
Varieties

Artificial Pancreas to Change Life of Diabetic Children

A patient receives a test for diabetes during the Care Harbor LA free medical clinic in Los Angeles, on September 11, 2014. Mario Anzuoni/Reuters
A patient receives a test for diabetes during the Care Harbor LA free medical clinic in Los Angeles, on September 11, 2014. Mario Anzuoni/Reuters
TT
TT

Artificial Pancreas to Change Life of Diabetic Children

A patient receives a test for diabetes during the Care Harbor LA free medical clinic in Los Angeles, on September 11, 2014. Mario Anzuoni/Reuters
A patient receives a test for diabetes during the Care Harbor LA free medical clinic in Los Angeles, on September 11, 2014. Mario Anzuoni/Reuters

An artificial pancreas developed by a team of Cambridge researchers is helping protect very young children with type 1 diabetes at a particularly vulnerable time of their lives.

A study published on Jan. 20 in the New England Journal of Medicine, found that it is both safe to use and more effective at managing their blood sugar levels than current technology.

Management of type 1 diabetes is challenging in very young children, because of a number of factors including the high variability in levels of insulin required and in how individual children respond to treatment, and their unpredictable eating and activity patterns. Children are particularly at risk of dangerously low blood sugar levels (hypoglycaemia) and high blood sugar levels (hyperglycaemia).

To manage children's glucose levels, doctors increasingly turn to devices that continuously monitor glucose levels and deliver insulin via a pump, which administers insulin through a cannula inserted into the skin. These devices have proved successful to an extent in older children, but not in very young children.

Current technology -- sensor-augmented pump therapy -- requires parents to review their child's glucose levels using a monitor and then manually adjust the amount of insulin administered by the pump.

Professor Roman Hovorka from the Wellcome-MRC Institute of Metabolic Science at the University of Cambridge has developed an app -- CamAPS FX -- which, combined with a glucose monitor and insulin pump, acts as an artificial pancreas, automatically adjusting the amount of insulin it delivers based on predicted or real-time glucose levels. It is a 'hybrid closed loop system', meaning that the child's caregiver will have to administer insulin at mealtimes, but at all other times the algorithm works by itself. There are no commercially available versions of fully closed loop systems yet.

Working across seven centers in the UK and Europe, Professor Hovorka and an international team of researchers recruited 74 children with type 1 diabetes, aged one to seven years, to take part in their trial.

The trial compared the safety and efficacy of hybrid closed-loop therapy with sensor-augmented pump therapy. All children used the CamAPS FX hybrid closed-loop system for 16 weeks, and then used the control treatment (sensor-augmented pump therapy) for 16 weeks.

Most Viewed

 
 
Varieties

Jimmy Carter's Woodworking, Painting and Poetry Reveal an Introspective Renaissance Man

(FILES) Former President Jimmy Carter waves to the crowd at the Democratic National Convention 2008 at the Pepsi Center in Denver, Colorado, on August 25, 2008. (Photo by Robyn BECK / AFP)
(FILES) Former President Jimmy Carter waves to the crowd at the Democratic National Convention 2008 at the Pepsi Center in Denver, Colorado, on August 25, 2008. (Photo by Robyn BECK / AFP)
TT
TT

Jimmy Carter's Woodworking, Painting and Poetry Reveal an Introspective Renaissance Man

(FILES) Former President Jimmy Carter waves to the crowd at the Democratic National Convention 2008 at the Pepsi Center in Denver, Colorado, on August 25, 2008. (Photo by Robyn BECK / AFP)
(FILES) Former President Jimmy Carter waves to the crowd at the Democratic National Convention 2008 at the Pepsi Center in Denver, Colorado, on August 25, 2008. (Photo by Robyn BECK / AFP)

The world knew Jimmy Carter as a president and humanitarian, but he also was a woodworker, painter and poet, creating a body of artistic work that reflects deeply personal views of the global community — and himself.
His portfolio illuminates his closest relationships, his spartan sensibilities and his place in the evolution of American race relations. And it continues to improve the finances of The Carter Center, his enduring legacy, The Associated Press said.
Creating art provided “the rare opportunity for privacy” in his otherwise public life, Carter said. “These times of solitude are like being in another very pleasant world.”
‘One of the best gifts of my life' Mourners at Carter’s hometown funeral will see the altar cross he carved in maple and collection plates he turned on his lathe. Great-grandchildren in the front pews at Maranatha Baptist Church slept as infants in cradles he fashioned.
The former president measured himself a “fairly proficient” craftsman. Chris Bagby, an Atlanta woodworker whose shop Carter frequented, elevated that assessment to “rather accomplished.”
Carter gleaned the basics on his father’s farm, where the Great Depression meant being a jack-of-all-trades. He learned more in shop class and with Future Farmers of America. “I made a miniature of the White House,” he recalled, insisting it was not about his ambitions.
During his Navy years, Jimmy and Rosalynn Carter chose unfurnished military housing to stretch his $300 monthly wage, and he built their furniture himself in a shop on base.
As president, Carter nurtured woodworking rather than his golf game, spending hours in a wood shop at Camp David to make small presents for family and friends. And when he left the White House, West Wing aides and Cabinet members pooled money for a shopping spree at Sears, Roebuck & Co. so he could finally assemble a full-scale home woodshop.
“One of the best gifts of my life,” Carter said.
Working in their converted garage, he previewed decades of Habitat for Humanity work by refurbishing their one-story house in Plains. He also improved his fine woodworking skills, joining wood without nails or screws. He also bought Japanese carving tools, and fashioned a chess set later owned by a Saudi prince.
Not just any customer Carter frequented Atlanta’s Highland Woodworking, a shop replete with a library of how-to books and hard-to-find tools, and recruited the world’s preeminent handmade furniture maker, Tage Frid, as an instructor, Bagby said.
Still hanging near the store entrance is a picture of Frid, who died in 2004, teaching students including a smiling former president at the front of the class.
“He was like a regular customer,” Bagby said, other than the “Secret Service agents who came with him.”
Carter built four ladder-back chairs out of hickory in 1983, and Sotheby’s auctioned them for $21,000 each at the time, the first of many sales of Carter paintings and furniture that raised millions to benefit The Carter Center.
It was rarely about the money, though. Jill Stuckey, a longtime friend who would have the Carters over to her home in Plains, recalled seeing the former president carrying out one of her chairs.
“I said, ‘What are you doing?’” she recalled. “He said, ‘It’s broken. I’m going to take it home and fix it.’”
He was at her back door at 7:30 the next morning, holding her repaired chair.
Carter compared woodworking to the results of his labor as a Navy engineer, or as a boy on the farm: “I like to see what I have done, what I have made.”
‘No special talent,' but his paintings drive auctions Carter employed a folk-art style as a late-in-life amateur painter and claimed “no special talent,” but a 2020 Carter Center auction drew $340,000 for his painting titled “Cardinals," and his oil-on-canvas of an eagle sold for $225,000 in 2023, months after he entered hospice care.
Carter’s work hangs throughout the center’s campus. A room where he met with dignitaries is encircled with birds he painted after he and Rosalynn took on bird watching as a hobby.
Near the executive offices are a self-portrait and a painting of Rosalynn in their early post-presidential years, hanging across from a trio of Andy Warhol prints showing Carter in office.
Carter’s earliest years predominate, with boyhood farm scenes and portraits of influential figures like his father James Earl Carter Sr., whose death in 1953 led him to abandon a Navy career and eventually enter politics in Georgia.
Some of his subjects, including both of his parents, are looking away. Carter's likeness of his mother shows “Miss Lillian” as a 70-year-old Peace Corps volunteer in India. Jason Carter said the piece was particularly meaningful to his grandfather, who lost reelection at a relatively youthful 56.
“When he got out of the White House, she was standing there saying, ’Well, I turned 70 in the Peace Corps. What are you going to do?” Jason Carter said.
One Carter subject who meets his gaze is a young Rosalynn — they married when she was 18 and he was 21. He described her as “remarkably beautiful, almost painfully shy, obviously intelligent, and yet unrestrained in our discussions.”
Another who doesn’t look away is Rachel Clark, a Black sharecropper who had hosted the future president after they worked in the fields. “Except for my parents, Rachel Clark was the person closest to me,” Carter wrote of his childhood.
'Just a word of praise' Carter wrote more than 30 books — even a novel — but was most introspective in poetry.
On his first real recognition of Jim Crow segregation: “A silent line was drawn between friend and friend, race and race.”
On his Cold War submarine’s delicate dance with enemies: “We wanted them to understand ... to share our love of solitude ... the peace we yearned to keep.”
Rosalynn’s smile, he gushed, silenced the birds, “or may be I failed to hear their song.”
Perhaps Carter’s most revealing poem, “I Wanted to Share My Father’s World,” concerns the man who never got to see his namesake son’s achievements. He wrote that he despised Earl’s discipline, and swallowed hunger for “just a word of praise.”
Only when he brought his own sons to visit his dying father did he “put aside the past resentments of the boy” and see “the father who will never cease to be alive in me.”