Remotely Heated Seeds to Treat Brain Tumors

A tumor seen on an MRI scan. (Getty/iStock)
A tumor seen on an MRI scan. (Getty/iStock)
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Remotely Heated Seeds to Treat Brain Tumors

A tumor seen on an MRI scan. (Getty/iStock)
A tumor seen on an MRI scan. (Getty/iStock)

A tiny magnetic seed could hold the key to treating tumors in some of the most inaccessible parts of the body. According to Sky News, minimally invasive image-guided ablation, or "Minima", is a new therapy which sees the 2mm seed guided through the brain to heat and destroy tumors.

Tested on mice, it involves using an MRI scanner to navigate the seed's path to the tumor, before heating it remotely and using this heat to kill off the cancer cells. The technique could mean more effective treatment, reduced recovery times, and less chance of side effects.

It could be used against hard-to-reach glioblastoma - the most common form of brain cancer - as well as prostate cancer and other tumors that would benefit from less invasive treatment. The findings are detailed in a study published in the journal Advanced Science. Senior author, Professor Mark Lythgoe from the UCL Centre for Advanced Biomedical Imaging, told the PA news agency: "By having precise remote control of the seed using the MRI scanner, we can destroy only the cancer cells. This means that we will be able to preserve the healthy tissue.”

"In terms of neurosurgery this means that we will be able to preserve motor function and cognitive function which not only contribute to the quality of life and recovery time but can contribute to the long-term survival of the patient," he added.

Co-author Dr. Lewis Thorne is a consultant neurosurgeon at the National Hospital for Neurology and Neurosurgery who treats patients with glioblastoma.

"Minima can successfully destroy cancer in a mouse and has the potential to extend survival and limit damage to adjacent brain tissues in patients," Lythgoe added.
Professor Mark Emberton, UCL Division of Surgery and Interventional Science - lead cancer clinician in the study, said: "Improving the precision of our cancer treatments is arguably one of the greatest unmet needs we have today. "

One in eight men will be diagnosed with prostate cancer.

"While treatments such as radiotherapy and surgery can be effective, they often cause unwanted and debilitating side effects such as incontinence and impotence. Minima may allow us to precisely target and destroy prostate tumor tissue, reducing harm to normal cells,” Emberton concluded.



Mount Fuji Hikers to be Charged $27 on All Trails

(FILES) A chimney is seen at the Keihin Industrial Zone as Mount Fuji (background L), Japan's highest mountain at 3,776 meters (12,388 feet), looms in the background as viewed from the observation deck of Kawasaki Marien in Kawasaki on January 24, 2022. (Photo by Philip FONG / AFP)
(FILES) A chimney is seen at the Keihin Industrial Zone as Mount Fuji (background L), Japan's highest mountain at 3,776 meters (12,388 feet), looms in the background as viewed from the observation deck of Kawasaki Marien in Kawasaki on January 24, 2022. (Photo by Philip FONG / AFP)
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Mount Fuji Hikers to be Charged $27 on All Trails

(FILES) A chimney is seen at the Keihin Industrial Zone as Mount Fuji (background L), Japan's highest mountain at 3,776 meters (12,388 feet), looms in the background as viewed from the observation deck of Kawasaki Marien in Kawasaki on January 24, 2022. (Photo by Philip FONG / AFP)
(FILES) A chimney is seen at the Keihin Industrial Zone as Mount Fuji (background L), Japan's highest mountain at 3,776 meters (12,388 feet), looms in the background as viewed from the observation deck of Kawasaki Marien in Kawasaki on January 24, 2022. (Photo by Philip FONG / AFP)

Hikers attempting any of Mount Fuji's four main trails will be charged an entry fee of 4,000 yen ($27) from this summer, after local authorities passed a bill on Monday.

A record influx of foreign tourists to Japan has sparked alarm about overcrowding on the nation's highest mountain, a once-peaceful pilgrimage site.

Last year, Yamanashi region -- home to Mount Fuji -- introduced a 2,000 yen ($14) entry fee plus an optional donation for the active volcano's most popular hiking route, the Yoshida Trail.

A cap on daily entries and online reservations were also brought in on that trail by officials concerned about safety and environmental damage on Fuji's majestic slopes.

The Yoshida Trail fee will be doubled for this year's July-September climbing season, while neighboring Shizuoka region passed a bill on Monday to also charge 4,000 yen for its three trails, which were previously free, AFP reported.

Thanks in part to the new restrictions, the number of climbers who tackled Mount Fuji declined to 204,316 last year, from 221,322 in 2023, environment ministry data shows.

Although climber numbers continue to be eclipsed by pre-pandemic levels, "200,000 hikers is still huge", Natsuko Sodeyama, a Shizuoka prefecture official, told AFP.

"There is no other mountain in Japan that attracts that many people in the span of just over two months. So some restrictions are necessary to ensure their safety."

Mount Fuji is covered in snow for most of the year, but during the summer hiking season many trudge up its steep, rocky slopes through the night to see the sunrise.

The symmetrical mountain has been immortalized in countless artworks, including Hokusai's "Great Wave". It last erupted around 300 years ago.