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Milk May Exacerbate Multiple Sclerosis Symptoms, New Study Suggests

Bottles of milk are seen on a milk float during the morning delivery round in the town of Sawbridgeworth, Britain, April 22, 2020. REUTERS/Hannah McKay
Bottles of milk are seen on a milk float during the morning delivery round in the town of Sawbridgeworth, Britain, April 22, 2020. REUTERS/Hannah McKay
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Milk May Exacerbate Multiple Sclerosis Symptoms, New Study Suggests

Bottles of milk are seen on a milk float during the morning delivery round in the town of Sawbridgeworth, Britain, April 22, 2020. REUTERS/Hannah McKay
Bottles of milk are seen on a milk float during the morning delivery round in the town of Sawbridgeworth, Britain, April 22, 2020. REUTERS/Hannah McKay

Researchers at the University of Bonn have found a link between the consumption of dairy products and more severe multiple sclerosis (MS) symptoms in MS patients.

Multiple sclerosis sufferers often complain of more severe disease symptoms after consuming dairy products. Researchers have now found a possible cause for this and reported it in a paper published in the journal Proceedings of the National Academy of Sciences (PNAS).

According to the study, a protein in cow's milk can trigger inflammation that targets the 'insulating layer' around nerve cells. The study was able to demonstrate this link in mice, but also found evidence of a similar mechanism in humans. The researchers therefore recommend that certain groups of sufferers avoid dairy products.

During the study, lead author Stefanie Kürten from the Institute of Anatomy at University Hospital Bonn, injected mice with different proteins from cow's milk, to find out if there was a constituent that they were responding to with symptoms of disease. And the researchers did indeed find what they were looking for: When they administered the cow's milk constituent casein to the animals, the mice went on to develop neurological disorders. Electron microscopy showed damage to the insulating layer around the nerve fibers, the myelin.

In multiple sclerosis, the body's immune system destroys the myelin sheath. The consequences range from paresthesia and vision problems to movement disorders. In extreme cases, patients need a wheelchair. The insulating sheath was also massively perforated in the mice -- apparently triggered by casein administration.

“Casein is a key protein in cow’s milk, so I don’t know how easy its elimination can be to make an alternative suitable for those patients. However, we are currently studying whether a specific type of casein is the culprit behind the aggravated symptoms. In this case, we can only eliminate this type to address the problem,” Kürten told Asharq Al-Awsat.

“But, for now, we recommend MS patients to consume non-dairy substitutes like soy milk, oat milk, and almond milk,” she added.

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Scientists Seek Miracle Pill to Stop Methane Cow Burps

A cow that's part of study on reducing methane emitted by cow burps stands in an exclosure at UC Davis in Davis, California on October 23, 2024. (AFP)
A cow that's part of study on reducing methane emitted by cow burps stands in an exclosure at UC Davis in Davis, California on October 23, 2024. (AFP)
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Scientists Seek Miracle Pill to Stop Methane Cow Burps

A cow that's part of study on reducing methane emitted by cow burps stands in an exclosure at UC Davis in Davis, California on October 23, 2024. (AFP)
A cow that's part of study on reducing methane emitted by cow burps stands in an exclosure at UC Davis in Davis, California on October 23, 2024. (AFP)

A scientist guides a long tube into the mouth and down to the stomach of Thing 1, a two-month-old calf that is part of a research project aiming to prevent cows from burping methane, a potent greenhouse gas.

Paulo de Meo Filho, a postdoctoral researcher at University of California, Davis, is part of an ambitious experiment aiming to develop a pill to transform cow gut bacteria so it emits less or no methane.

While the fossil fuel industry and some natural sources emit methane, cattle farming has become a major climate concern due to the sheer volume of the cows' emissions.

"Almost half of the increase in (global) temperature that we've had so far, it's been because of methane," said Ermias Kebreab, an animal science professor at UC Davis.

Methane, the second largest contributor to climate change after carbon dioxide, breaks down faster than CO2 but is more potent.

"Methane lives in the atmosphere for about 12 years" unlike carbon dioxide which persists for centuries, Kebreab said.

"If you start reducing methane now, we can actually see the effect on the temperature very quickly."

Filho uses the tube to extract liquid from Thing 1's rumen -- the first stomach compartment containing partially digested food.

Using the rumen liquid samples, the scientists are studying the microbes that convert hydrogen into methane, which is not digested by the cow but instead burped out.

A single cow will burp roughly 220 pounds (100 kilograms) of the gas annually.

- 'Social critters' -

Thing 1 and other calves receive a seaweed-supplemented diet to reduce methane production.

Scientists hope to achieve similar results by introducing genetically modified microbes that soak up hydrogen, starving methane-producing bacteria at the source.

However, the team proceeds cautiously.

"We can't just simply cut down methane production by removing" methane-making bacteria, as hydrogen could accumulate to the point of harming the animal, warned Matthias Hess, who runs the UC Davis lab.

"Microbes are kind of social critters. They really like to live together," he said.

"The way they interact and affect each other impacts the overall function of the ecosystem."

Hess's students test different formulas in bioreactors, vessels that reproduce microorganisms' living conditions in a stomach from movements to temperature.

- More productive cows -

The project is being carried out at UC Davis as well as UC Berkeley's Innovative Genomics Institute (IGI).

IGI scientists are trying to identify the right microbe -- the one they hope to genetically alter to supplant methane-producing microbes.

The modified microorganisms will then be tested at UC Davis in the lab and in the animals.

"Not only are we trying to reduce methane emissions, but you also increase the feed efficiency," said Kebreab.

"Hydrogen and methane, they are both energy, and so if you reduce that energy and redirect it to something else... we have a better productivity and lower emissions at the same time."

The ultimate goal is a single-dose treatment administered early in life, since most cattle graze freely and can't receive daily supplements.

The three research teams have been given $70 million and seven years to achieve a breakthrough.

Kebreab has long studied sustainable livestock practices and pushes back against calls to reduce meat consumption to save the planet.

While acknowledging this might work for healthy adults in developed nations, he pointed to countries like Indonesia, where the government is seeking to increase meat and dairy production because 20 percent of children under five suffer from stunted growth.

"We can't tell them to not eat meat," he said.