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Discovery of Prostate Cancer Linked-Bacteria Could Pave Way for Treatment

Scientists work at a laboratory south of Cambridge, Britain, March 12, 2021. (Reuters)
Scientists work at a laboratory south of Cambridge, Britain, March 12, 2021. (Reuters)
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Discovery of Prostate Cancer Linked-Bacteria Could Pave Way for Treatment

Scientists work at a laboratory south of Cambridge, Britain, March 12, 2021. (Reuters)
Scientists work at a laboratory south of Cambridge, Britain, March 12, 2021. (Reuters)

Scientists have discovered bacteria linked to aggressive prostate cancer in work hailed as a potential revolution for the prevention and treatment of the disease, reported The Guardian.

Researchers led by the University of East Anglia performed sophisticated genetic analyses on the urine and prostate tissue of more than 600 men with and without prostate cancer and found five species of bacteria linked to rapid progression of the disease.

The study does not prove that the bacteria drive or exacerbate prostate cancer, but if work now under way confirms their role, researchers can develop tests to identify men most at risk and potentially find antibiotics to prevent the cancer from claiming thousands of lives each year.

“This is an exciting discovery that has the potential to truly revolutionize treatment for men,” said Dr. Hayley Luxton of Prostate Cancer UK, which co-funded the research.

Writing in the journal European Urology Oncology, the scientists describe how their genetic investigations found five species of bacteria – three new to science – that were associated with advanced prostate cancer. Men who had one or more of the species in their urine, prostate or tumor tissue were 2.6 times more likely to see their early-stage cancer progress to advanced disease than men who did not.

Lead scientist Colin Cooper, a professor of cancer genetics at the University of East Anglia, said it was possible the bacteria are not involved in the disease. For example, men with more aggressive prostate cancer may have immune system deficiencies that allow certain bacteria to thrive.

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'It's a Bird! It's a Plane!' it's Both, with Pilot Tossing Turkeys to Rural Alaska Homes

This image taken from video provided by Mountain Mind Media/Alaska Gear Company shows a plane from Alaska Turkey Bomb, which was started by Esther Keim to air drop frozen turkeys for Thanksgiving to people living in remote rural Alaska, flying in November 2024, in Alaska. (Mountain Mind Media/Alaska Gear Company via AP)
This image taken from video provided by Mountain Mind Media/Alaska Gear Company shows a plane from Alaska Turkey Bomb, which was started by Esther Keim to air drop frozen turkeys for Thanksgiving to people living in remote rural Alaska, flying in November 2024, in Alaska. (Mountain Mind Media/Alaska Gear Company via AP)
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'It's a Bird! It's a Plane!' it's Both, with Pilot Tossing Turkeys to Rural Alaska Homes

This image taken from video provided by Mountain Mind Media/Alaska Gear Company shows a plane from Alaska Turkey Bomb, which was started by Esther Keim to air drop frozen turkeys for Thanksgiving to people living in remote rural Alaska, flying in November 2024, in Alaska. (Mountain Mind Media/Alaska Gear Company via AP)
This image taken from video provided by Mountain Mind Media/Alaska Gear Company shows a plane from Alaska Turkey Bomb, which was started by Esther Keim to air drop frozen turkeys for Thanksgiving to people living in remote rural Alaska, flying in November 2024, in Alaska. (Mountain Mind Media/Alaska Gear Company via AP)

In the remotest reaches of Alaska, there’s no relying on DoorDash to have Thanksgiving dinner — or any dinner — delivered. But some residents living well off the grid nevertheless have turkeys this holiday, thanks to the Alaska Turkey Bomb, The Associated Press reported.
For the third straight year, a resident named Esther Keim has been flying low and slow in a small plane over rural parts of south-central Alaska, dropping frozen turkeys to those who can't simply run out to the grocery store.
Alaska is mostly wilderness, with only about 20% of it accessible by road. In winter, many who live in remote areas rely on small planes or snowmobiles to travel any distance, and frozen rivers can act as makeshift roads.
When Keim was growing up on an Alaska homestead, a family friend would airdrop turkeys to her family and others nearby for the holidays. Other times, the pilot would deliver newspapers, sometimes with a pack of gum inside for Keim.
Her family moved to more urban Alaska nearly 25 years ago but still has the homestead. Using a small plane she had rebuilt with her father, Keim launched her turkey delivery mission a few years back after learning of a family living off the land nearby who had little for Thanksgiving dinner.
“They were telling me that a squirrel for dinner did not split very far between three people," Keim recalled. “At that moment, I thought ... ‘I’m going to airdrop them a turkey.'”
She decided not to stop there. Her effort has grown by word of mouth and by social media posts. This year, she's delivering 32 frozen turkeys to people living year-round in cabins where there are no roads.
All but two had been delivered by Tuesday, with delivery plans for the last two birds thwarted by Alaska’s unpredictable weather.
Among the beneficiaries are Dave and Christina Luce, who live on the Yentna River about 45 miles (72 kilometers) northwest of Anchorage. They have stunning mountain views in every direction, including North America's tallest mountain, Denali, directly to the north. But in the winter it's a 90-minute snowmobile ride to the nearest town, which they do about once a month.
“I’m 80 years old now, so we make fewer and fewer trips," Dave Luce said. “The adventure has sort of gone out of it.”
They've known Keim since she was little. The 12-pound (5.44-kilogram) turkey she delivered will provide more than enough for them and a few neighbors.
“It makes a great Thanksgiving,” Dave Luce said. “She’s been a real sweetheart, and she’s been a real good friend.”
Keim makes 30 to 40 turkey deliveries yearly, flying as far as 100 miles (161 kilometers) from her base north of Anchorage toward Denali's foothills.
Sometimes she enlists the help of a “turkey dropper” to ride along and toss the birds out. Other times, she’s the one dropping turkeys while her friend Heidi Hastings pilots her own plane.
Keim buys about 20 turkeys at a time, with the help of donations, usually by people reaching out to her through Facebook. She wraps them in plastic garbage bags and lets them sit in the bed of her pickup until she can arrange a flight.
“Luckily it’s cold in Alaska, so I don’t have to worry about freezers,” she said.
She contacts families on social media to let them know of impending deliveries, and then they buzz the house so the homeowners will come outside.
“We won’t drop the turkey until we see them come out of the house or the cabin, because if they don’t see it fall, they’re not going to know where to look,” she said.
It can be especially difficult to find the turkey if there’s deep snow. A turkey was once missing for five days before it was found, but the only casualty so far has been a lost ham, AP quoted Keim as saying.
Keim prefers to drop the turkey on a frozen lake if possible so it's easy to locate.
“As far as precision and hitting our target, I am definitely not the best aim,” she joked. “I’ve gotten better, but I have never hit a house, a building, person or dog.”
Her reward is the great responses she gets from families, some who record her dropping the turkeys and send her videos and texts of appreciation.
“They just think it’s so awesome that we throw these things out of the plane,” Keim said.
Ultimately, she hopes to set up a nonprofit organization to solicit more donations and reach people across a bigger swath of the state. And it doesn’t have to stop at turkeys.
“There’s so many kids out in the villages," she said. “It would be cool to maybe add a stuffed animal or something they can hold.”