Scientists Develop 'Space Bricks' for Construction on Mars

An illustration of NASA’s “Perseverance” rover casting off its spacecraft’s cruise stage, minutes before entering the Martian atmosphere, photo obtained on Feb. 15, 2021. (NASA Handout via AFP)
An illustration of NASA’s “Perseverance” rover casting off its spacecraft’s cruise stage, minutes before entering the Martian atmosphere, photo obtained on Feb. 15, 2021. (NASA Handout via AFP)
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Scientists Develop 'Space Bricks' for Construction on Mars

An illustration of NASA’s “Perseverance” rover casting off its spacecraft’s cruise stage, minutes before entering the Martian atmosphere, photo obtained on Feb. 15, 2021. (NASA Handout via AFP)
An illustration of NASA’s “Perseverance” rover casting off its spacecraft’s cruise stage, minutes before entering the Martian atmosphere, photo obtained on Feb. 15, 2021. (NASA Handout via AFP)

In collaboration with the Indian Space Research Organization (ISRO), a team of researchers from the Indian Institute of Science (IISc) has developed a sustainable method for making bricks out of Martian soil, using bacteria and urea.

These “space bricks” can be used to construct building-like structures on Mars that could facilitate human settlement on the red planet.

The method for making these space bricks has been outlined in a study published in the journal PLOS One.

A slurry is first created by mixing Martian soil with guar gum, a bacterium called Sporosarcina pasteurii, urea and nickel chloride (NiCl2). This slurry can be poured into molds of any desired shape, and over a few days the bacteria convert the urea into crystals of calcium carbonate. These crystals, along with biopolymers secreted by the microbes, act as cement holding the soil particles together.

An advantage of this method is the reduced porosity of the bricks, which has been a problem with other methods used to consolidate Martian soil into bricks, says Aloke Kumar, associate professor in the Department of Mechanical Engineering at IISc, one of the senior authors of the paper.

The research group had previously worked on making bricks out of lunar soil, using a similar method. However, the previous method could only produce cylindrical bricks, while the current slurry-casting method can also produce bricks of complex shapes.

The slurry-casting method was developed with the help of Koushik Viswanathan, assistant professor in the Department of Mechanical Engineering, IISc, whose lab works on advanced manufacturing processes. In addition, extending the method to Martian soil proved challenging.

“Martian soil contains a lot of iron, which causes toxicity to organisms. In the beginning, our bacteria did not grow at all. Adding nickel chloride was the key step in making the soil hospitable to the bacteria,” explains Kumar.

The group plans to investigate the effect of Mars’ atmosphere and low gravity on the strength of the space bricks. The Martian atmosphere is 100 times thinner than Earth’s atmosphere, and contains over 95% carbon dioxide, which may significantly affect bacterial growth.

The researchers have constructed a device called MARS (Martian AtmospheRe Simulator), which consists of a chamber that reproduces the atmospheric conditions found on Mars in the lab. The team has also developed a lab-on-a-chip device that aims to measure bacterial activity in micro-gravity conditions.

“The device is being developed keeping in mind our intention to perform experiments in micro-gravity conditions in the near future. With ISRO’s help, the team plans to send such devices into space, so that they can study the effect of low gravity on the bacterial growth,” explains Rashmi Dikshit, a co-author of the study.

“I'm so excited that many researchers across the world are thinking about colonizing other planets. It may not happen quickly, but people are actively working on it,” says Kumar.



Blood Tests Allow 30-year Estimates of Women's Cardio Risks, New Study Says

A woman jogs in a park in Saint-Sebastien-sur-Loire near Nantes, France January 19, 2024. REUTERS/Stephane Mahe/File Photo Purchase Licensing Rights
A woman jogs in a park in Saint-Sebastien-sur-Loire near Nantes, France January 19, 2024. REUTERS/Stephane Mahe/File Photo Purchase Licensing Rights
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Blood Tests Allow 30-year Estimates of Women's Cardio Risks, New Study Says

A woman jogs in a park in Saint-Sebastien-sur-Loire near Nantes, France January 19, 2024. REUTERS/Stephane Mahe/File Photo Purchase Licensing Rights
A woman jogs in a park in Saint-Sebastien-sur-Loire near Nantes, France January 19, 2024. REUTERS/Stephane Mahe/File Photo Purchase Licensing Rights

Women’s heart disease risks and their need to start taking preventive medications should be evaluated when they are in their 30s rather than well after menopause as is now the practice, said researchers who published a study on Saturday.

Presenting the findings at the European Society of Cardiology annual meeting in London, they said the study showed for the first time that simple blood tests make it possible to estimate a woman’s risk of cardiovascular disease over the next three decades.

"This is good for patients first and foremost, but it is also important information for (manufacturers of) cholesterol lowering drugs, anti-inflammatory drugs, and lipoprotein(a)lowering drugs - the implications for therapy are broad," said study leader Dr. Paul Ridker of Brigham and Women’s Hospital in Boston, Reuters reported.

Current guidelines “suggest to physicians that women should generally not be considered for preventive therapies until their 60s and 70s. These new data... clearly demonstrate that our guidelines need to change,” Ridker said. “We must move beyond discussions of 5 or 10 year risk."

The 27,939 participants in the long-term Women’s Health Initiative study had blood tests between 1992 and 1995 for low density lipoprotein cholesterol (LDL-C or “bad cholesterol”), which are already a part of routine care.

They also had tests for high-sensitivity C-reactive protein (hsCRP) - a marker of blood vessel inflammation - and lipoprotein(a), a genetically determined type of fat.

Compared to risks in women with the lowest levels of each marker, risks for major cardiovascular events like heart attacks or strokes over the next 30 years were 36% higher in women with the highest levels of LDL-C, 70% higher in women with the highest levels of hsCRP, and 33% higher in those with the highest levels of lipoprotein(a).

Women in whom all three markers were in the highest range were 2.6 times more likely to have a major cardiovascular event and 3.7 times more likely to have a stroke over the next three decades, according to a report of the study in The New England Journal of Medicine published to coincide with the presentation at the meeting.

“The three biomarkers are fully independent of each other and tell us about different biologic issues each individual woman faces,” Ridker said.

“The therapies we might use in response to an elevation in each biomarker are markedly different, and physicians can now specifically target the individual person’s biologic problem.”

While drugs that lower LDL-C and hsCRP are widely available - including statins and certain pills for high blood pressure and heart failure - drugs that reduce lipoprotein(a) levels are still in development by companies, including Novartis , Amgen , Eli Lilly and London-based Silence Therapeutics.

In some cases, lifestyle changes such as exercising and quitting smoking can be helpful.

Most of the women in the study were white Americans, but the findings would likely “have even greater impact among Black and Hispanic women for whom there is even a higher prevalence of undetected and untreated inflammation,” Ridker said.

“This is a global problem,” he added. “We need universal screening for hsCRP ... and for lipoprotein(a), just as we already have universal screening for cholesterol.”