British Scientists Plan to Expand Genomic Sequencing from COVID to Flu 

A computer image created by Nexu Science Communication together with Trinity College in Dublin, shows a model structurally representative of a betacoronavirus which is the type of virus linked to COVID-19, shared with Reuters on February 18, 2020. (NEXU Science Communication/via Reuters)
A computer image created by Nexu Science Communication together with Trinity College in Dublin, shows a model structurally representative of a betacoronavirus which is the type of virus linked to COVID-19, shared with Reuters on February 18, 2020. (NEXU Science Communication/via Reuters)
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British Scientists Plan to Expand Genomic Sequencing from COVID to Flu 

A computer image created by Nexu Science Communication together with Trinity College in Dublin, shows a model structurally representative of a betacoronavirus which is the type of virus linked to COVID-19, shared with Reuters on February 18, 2020. (NEXU Science Communication/via Reuters)
A computer image created by Nexu Science Communication together with Trinity College in Dublin, shows a model structurally representative of a betacoronavirus which is the type of virus linked to COVID-19, shared with Reuters on February 18, 2020. (NEXU Science Communication/via Reuters)

Genomic sequencing allowed the world to track new coronavirus variants throughout the pandemic. Now British researchers plan to use it to better understand a host of other respiratory pathogens, from influenza to respiratory syncytial virus (RSV). 

The work is aimed at shedding more light on known threats and, potentially, emerging ones, the team at the Wellcome Sanger Institute, working with the UK Health Security Agency, said. 

The world has never had access to the kind of real-time information for these viruses that scientists obtained on SARS-CoV-2 through sequencing millions of genomes, Ewan Harrison, head of the new Respiratory Virus and Microbiome Initiative, told reporters on Monday. 

That includes granular detail on how they transmit as well as how they evolve in the face of the human immune response. 

"We hope that by expanding our ability to sequence these viruses routinely, we can build upon the work that's going on COVID, and hopefully supercharge research efforts to understand the transmission of these viruses, but also to help develop new treatments and vaccines," Harrison said. 

The aim is to make genomic surveillance of this type the norm, to inform public health responses and act as a blueprint for other countries that want to do the same thing, he said. 

The work will begin later this year by using leftover material from swabs taken for COVID-19 diagnostic purposes, sequencing SARS-CoV-2, influenza, RSV and other common respiratory viruses in a combined process. 

While some of the viruses targeted typically cause mild, cold-like symptoms, others can cause serious illness, particularly in vulnerable populations. 

Cases of COVID-19, flu and RSV have all surged this winter in the northern hemisphere in a so-called "tripledemic" that is putting serious pressure on hospitals in a number of countries. 

The team said that, in future, the initiative could answer questions about outbreaks like this. 

It also aims to sequence everything found in a single nose swab, including the viral, bacterial and fungal species present and how they change during infection. 

The five-year initiative aims to begin work from spring this year and is funded by Wellcome. 



German Backpacker Escapes Australian Bush Ordeal by 'Sheer Luck'

German backpacker Carolina Wilga lost hope of rescue after 11 nights in the Australian bush. Handout / WESTERN AUSTRALIAN POLICE FORCE/AFP
German backpacker Carolina Wilga lost hope of rescue after 11 nights in the Australian bush. Handout / WESTERN AUSTRALIAN POLICE FORCE/AFP
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German Backpacker Escapes Australian Bush Ordeal by 'Sheer Luck'

German backpacker Carolina Wilga lost hope of rescue after 11 nights in the Australian bush. Handout / WESTERN AUSTRALIAN POLICE FORCE/AFP
German backpacker Carolina Wilga lost hope of rescue after 11 nights in the Australian bush. Handout / WESTERN AUSTRALIAN POLICE FORCE/AFP

German backpacker Carolina Wilga lost hope of rescue after 11 nights in the Australian bush, and only made it out by "sheer luck", police said Saturday.

The 26-year-old walked "confused and disoriented" 24 kilometers (15 miles) away from her van after it got stuck in remote bushland in Western Australia, AFP reported.

As police searched for her by air, the backpacker's ordeal ended Friday when she managed to flag down a woman driving by who took her to police.

"She is still in disbelief that she was able to survive. In her mind, she had convinced herself that she was not going to be located," said Jessica Securo, acting inspector for the Western Australia police.

The rescue was down to "sheer luck".

"I actually spoke to Carolina this morning, so she confirmed that she was very confused and disorientated," Securo told a news conference.

"She basically looked at the direction of the sun and tried to head west, thinking that that would be her best bet of coming across someone or a road."

Wilga had been last seen on June 29 arriving in the van at a general store in the small agricultural community of Beacon, northeast of Perth.

Police found the van on Thursday, abandoned after getting stuck in dense bushland north of Beacon, with plastic orange traction tracks placed beneath the rear wheels.

"It appears that she has somewhat lost control of the vehicle, and then it's become mechanically unsound, and bogged," Securo said.

- 'Overwhelmed' -

She stayed with the van for one day before leaving the vehicle through "panic", hoping to find help.

Wilga was found "exhausted, dehydrated and hungry", suffering from cuts and bruises, but "overwhelmed" to have found someone to help her.

"She had minimal food and minimal water. From speaking to her, she has said she could have planned better."

The terrain "can be quite dangerous", Securo added.

Wilga remained in a Perth hospital and was not expected to be released on Saturday, still needing "emotional support" and treatment for some injuries.

"She's had a good night's sleep. She's had a shower. We've got her some food, which was a massive relief for her. So she's just taking it one day at a time at the moment."

The backpacker is now in "frequent communication" with her family who are relieved and thankful the Western Australian community came together to "throw every resource at locating their daughter", Securo said.

The family had no plans at this stage to travel to Australia.

Police say Wilga had spent two years backpacking around the country, and was working at mine sites in Western Australia while staying mostly at hostels.

"Carolina has told me that she loves Australia. She still has so much travel to do here. She hasn't made it over to the east coast yet, so that's still on her bucket list."