Iran’s Rare Cheetah Cub Dies of Kidney Failure

In this photo provided by Iranian Students' News Agency, ISNA, Iran's only Asiatic cheetah cub in captivity, Pirouz, looks on at the Pardisan Park in Tehran, Iran, on Dec. 21, 2022. (Iranian Students' News Agency, ISNA via AP)
In this photo provided by Iranian Students' News Agency, ISNA, Iran's only Asiatic cheetah cub in captivity, Pirouz, looks on at the Pardisan Park in Tehran, Iran, on Dec. 21, 2022. (Iranian Students' News Agency, ISNA via AP)
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Iran’s Rare Cheetah Cub Dies of Kidney Failure

In this photo provided by Iranian Students' News Agency, ISNA, Iran's only Asiatic cheetah cub in captivity, Pirouz, looks on at the Pardisan Park in Tehran, Iran, on Dec. 21, 2022. (Iranian Students' News Agency, ISNA via AP)
In this photo provided by Iranian Students' News Agency, ISNA, Iran's only Asiatic cheetah cub in captivity, Pirouz, looks on at the Pardisan Park in Tehran, Iran, on Dec. 21, 2022. (Iranian Students' News Agency, ISNA via AP)

The last survivor of three critically endangered Asiatic cheetah cubs born in captivity in Iran died in hospital Tuesday from kidney failure, state media reported.

"Pirouz who was admitted to the Central Veterinary Hospital due to kidney failure last Thursday, died after undergoing dialysis," the official IRNA news agency said.

"The loss of Pirouz and ineffectiveness of all the efforts made by the treatment team in the past few days to save the animal saddens me and all my colleagues, and we apologize to everyone that we could not keep this animal alive," hospital director Omid Moradi told IRNA.

Pirouz, meaning "victorious" in Persian, had become a source of national pride since its birth in May last year at a wildlife refuge in northeastern Iran.

Two other cubs born with him died that same month, but Pirouz survived at a time when only a dozen members of the species are left in the wild.

The Asiatic cheetah -- Acinonyx jubatus venaticus -- is threatened with "dangerous ongoing decline" and is critically endangered, according to the International Union for Conservation of Nature.

According to a 2017 study referenced by IUCN, the sub-species is confined only to Iran where there were "less than 50 mature individuals."

The world's fastest land animal, capable of reaching speeds of 120 kilometers (74 miles) per hour, cheetahs once stalked habitats from the eastern reaches of India to the Atlantic coast of Senegal.

They are still found in parts of southern Africa but have practically disappeared from North Africa and Asia.

Iran began a United Nations-supported cheetah protection program in 2001.

In January 2022, deputy environment minister Hassan Akbari said Iran was home to only a dozen Asiatic cheetahs -- down from an estimated 100 in 2010.

Iran's environment department had hoped the birth of the cubs in captivity would help increase the cheetah population.



Australian Climber on Record Sea-to-Summit Everest Bid

A member of expedition team stands at Khumbu Icefall in Solukhumbu district, also known as the Everest region, Nepal, April 22, 2026. REUTERS/Purnima Shrestha
A member of expedition team stands at Khumbu Icefall in Solukhumbu district, also known as the Everest region, Nepal, April 22, 2026. REUTERS/Purnima Shrestha
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Australian Climber on Record Sea-to-Summit Everest Bid

A member of expedition team stands at Khumbu Icefall in Solukhumbu district, also known as the Everest region, Nepal, April 22, 2026. REUTERS/Purnima Shrestha
A member of expedition team stands at Khumbu Icefall in Solukhumbu district, also known as the Everest region, Nepal, April 22, 2026. REUTERS/Purnima Shrestha

Among the hundreds of climbers hoping to scale Everest this season, 27-year-old Australian Oliver Foran began his journey far away, cycling and then walking all the way from the sea.

Foran is seeking to break the 67-day "sea-to-summit" record, first pedaling 1,150 kilometers (715 miles) from the warm waves of the Bay of Bengal in India to Nepal and now trekking to the icy 8,849-meter (29,032-foot) peak.

"I always wanted to climb Mount Everest, but I wanted to do it in a special way," Foran told AFP by telephone on a break from his long hike upwards to Everest Base Camp, and then to the highest place on Earth.

It is also a deeply personal journey, with Foran raising funds for youth mental health.

The former real estate agent climbed his first major mountain, Nepal's 6,189-meter (20,305-foot) Island Peak, in 2024.

He then summited 6,812-meter (22,349-foot) Ama Dablam last year.

He hopes Everest will be his first 8,000-meter mountain.

He has been training -- cycling, exercising and working on his breathing -- for the past six months to build endurance for the altitude.

The sea-to-summit is a rare feat, first completed by another Australian, Tim Macartney-Snape, in 1990. Macartney-Snape spent three months walking from sea level to the Everest summit, and it was his documentary that sparked the idea for Foran.

The current record is held by South Korean climber Kim Chang-ho, who walked and then kayaked the Ganges river, cycled to Nepal and then trekked up to the base camp in 2013, five years before his death on another mountain.

Foran aims to slash a week off that record and reach the summit in 60 days.

"It is a challenging task and a unique one," said Gelje Sherpa, his lead guide and expedition organizer at AGA Adventures.

"There are so many facilities and options to summit Everest in a record time now, but he is using only his own human power. That is big."

Foran cycled across India and Nepal in the first 16 days, navigating sweltering hot plains before steep, relentless hills.

He said he is driven by "something bigger" than himself, the memory of his teenage grief when his mother died of brain cancer.

"I didn't know how to process it... Life on the outside looked pretty good, but inside I was just emptier than ever," he said.

The unresolved grief reached a breaking point seven years later.

Foran said he had "made up my mind that that was it" -- but a call to a friend proved life-saving.

"I made the decision then that... if I ever got the opportunity to stop somebody else from getting to that point or to give them another way, I would," he said.

That commitment underlines his Everest expedition.

Foran is partnering with Australian organization Youturn with a target to raise $200,000 to build a youth mental health support center back home.

Aaron Minton, a director at Youturn, said it would be a "youth-focused mental health and well-being hub".

Foran hopes his journey can offer both awareness and inspiration, sharing the good parts and the struggles of his journey through his social media.

"What's really motivating me is, hopefully, having an inspiration on some of these younger people -- that might be a little bit stuck with where they are right now in their lives," he said.

"Also, I'm doing it for my mum, because she can't, and I want to make her proud."

As he continues his ascent, an unexpected source of comfort that accompanies him is the Madonna song "Like a Prayer".

"My mum used to listen to it. And it now holds a special place in my heart," he said.

"So that's what I'm going to be whistling to myself when I'm walking up to the summit."


Germany Approves New Rescue Bid for Stranded Whale

People stand close to a stranded humpback whale in the Wismarer Bucht bay of the Baltic Sea off the island of Poel, northern Germany, close to the village of Faehrdorf-Hof, on April 28, 2026. (AFP)
People stand close to a stranded humpback whale in the Wismarer Bucht bay of the Baltic Sea off the island of Poel, northern Germany, close to the village of Faehrdorf-Hof, on April 28, 2026. (AFP)
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Germany Approves New Rescue Bid for Stranded Whale

People stand close to a stranded humpback whale in the Wismarer Bucht bay of the Baltic Sea off the island of Poel, northern Germany, close to the village of Faehrdorf-Hof, on April 28, 2026. (AFP)
People stand close to a stranded humpback whale in the Wismarer Bucht bay of the Baltic Sea off the island of Poel, northern Germany, close to the village of Faehrdorf-Hof, on April 28, 2026. (AFP)

German officials Tuesday gave the green light for a fresh rescue attempt for a humpback whale which has been stranded off the country's Baltic Sea coast for over a month.

The 13-metre (over 40 foot) whale and its struggle for survival have gripped Germany since the sea mammal beached on a sandbank near the city of Luebeck, far from its natural habitat.

After several initial attempts failed, two entrepreneurs came forward to finance a new rescue bid which will involve loading the cetacean onto a special barge and carrying it out to deeper waters.

Till Backhaus, environment minister for the state of Mecklenburg-Western Pomerania, said that two vets had examined the whale and believed it was "fit to be transported."

After his announcement, rescuers in diving suits could be seen next to the whale, standing in shallow waters near the island of Poel, with the barge close by.

The creature, dubbed "Timmy" by some of the German press, was first spotted stuck on a sandbank on March 23 near Luebeck before freeing itself and then becoming stuck again several times.

At the start of April officials gave up on the animal, saying they believed it could not be saved.

But this triggered an outcry and authorities were persuaded to let the entrepreneurs come up with a rescue plan.

Some scientists have strongly criticized the decision to allow further rescue bids, believing they will be too risky for the whale and estimating the chances of success as low.

Backhaus however insisted it was his "absolute priority" that the mammal be rescued alive, and he was trying to "do everything possible to help" the creature.

The saga has sparked a media frenzy -- with non-stop coverage from TV channels, online outlets and social media influencers -- but has also led to angry spats and conspiracy theories.


New Treatment Brings Hope to Children with Cancer

Researchers have developed a new targeted cancer therapy that can precisely seek out and destroy tumor cells. (UBC)
Researchers have developed a new targeted cancer therapy that can precisely seek out and destroy tumor cells. (UBC)
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New Treatment Brings Hope to Children with Cancer

Researchers have developed a new targeted cancer therapy that can precisely seek out and destroy tumor cells. (UBC)
Researchers have developed a new targeted cancer therapy that can precisely seek out and destroy tumor cells. (UBC)

Researchers at the University of British Columbia (UBC) Faculty of Medicine in Canada have developed a new targeted cancer therapy that can precisely seek out and destroy tumor cells, showing strong results in preclinical studies that bring the breakthrough closer to human clinical trials.

The findings were published last Monday in the Cancer Discovery Journal.

The therapy targets a protein called IL1RAP, which is found on the surface of certain cancer cells, but is largely absent from normal tissues.

By linking a cancer-killing drug to an antibody that recognizes this protein, the team created an antibody-drug conjugate that delivers treatment directly to cancer cells while sparing healthy tissues.

In multiple models of Ewing sarcoma — a rare and aggressive cancer affecting children and young adults — the treatment eliminated established tumors and dramatically reduced the spread of cancer.

Similar effects were seen in other cancers, including lymphoma and tumors driven by specific genetic alterations (NTRK fusions).

“This is exactly the kind of target we look for, something that’s present on cancer cells but largely absent from normal tissues,” said senior author Dr Poul Sorensen, professor of pathology and laboratory medicine at UBC’s Faculty of Medicine and a distinguished scientist at BC Cancer. “It allows us to deliver treatment with a high degree of precision.”

“This isn’t a distant possibility,” said Sorensen, who also holds the Johal Endowed Chair in Childhood Cancer Research. “The data position this for clinical trials in the very near future, pending the next steps in development and regulatory approval.”

The approach builds on earlier work by Sorensen and his team, including first author Dr Haifeng Zhang from the Sorensen laboratory, which identified IL1RAP as a key protein that helps cancer cells survive in the bloodstream and spread to other parts of the body.

When cancer cells break away from a primary tumor, they must endure a hostile environment in the circulatory system before establishing new tumors elsewhere. IL1RAP appears to help them adapt and survive during this process.

Metastatic disease, which occurs when cancer spreads throughout the body, is the single most powerful predictor of poor outcome for cancer patients of all ages and has been a difficult process for researchers to study or for clinicians to target.

“We think of this protein almost like a protective shield,” said Zhang, a scientist in the Sorensen Lab. “It helps cancer cells withstand the stresses of travelling through the body and forming metastases. What we’ve done here is turn that shield into a target, using it to deliver a drug directly into those cells.”

Crucially, the therapy demonstrated a strong safety profile in preclinical testing, supporting its readiness for clinical development — an important step toward human trials.

The findings highlight a promising new strategy for targeting cancers driven by specific genetic alterations that expresses the IL1RAP protein, potentially opening the door to more precise, effective treatments for both pediatric and adult patients.