Magical Effects of Psychedelics Can Transform Psychiatry

Illustrative Ecstasy pills. (AP)
Illustrative Ecstasy pills. (AP)
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Magical Effects of Psychedelics Can Transform Psychiatry

Illustrative Ecstasy pills. (AP)
Illustrative Ecstasy pills. (AP)

Imagine a medicine that could help people process disturbing memories, sparking behavioral changes rather than merely burying and suppressing symptoms and trauma. For the millions suffering with post-traumatic stress disorder (PTSD) and depression, such remedies for their daily struggles could be on the horizon. Psychiatry is rapidly heading towards a new frontier – and it's all thanks to psychedelics, The Guardian reported.

In an advanced phase trial published in Nature in May, patients in the US, Israel and Canada who received doses of the psychedelic stimulant Ecstasy (MDMA), alongside care from a therapist, were more than twice as likely as the placebo group to no longer have PTSD - for which there is currently no effective treatment - months later.

The researchers concluded that the findings, which reflected those of six earlier-stage trials, cemented the treatment as a startlingly successful potential breakthrough therapy. There are now hopes that MDMA therapy could receive approval for certain treatments from US regulators by 2023, or perhaps even earlier – with psilocybin, the active ingredient of magic mushrooms, not far behind in the process. A small study at Johns Hopkins University, published last year, suggested it could be four times more effective than traditional antidepressants.

You could say interest in psychedelics is mushrooming. Last month, in a first for psychedelics since the war on drugs was launched in the 1970s, US federal funding was granted for a psilocybin study to treat tobacco addiction following pressure by lawmakers, including Alexandria Ocasio-Cortez.

This marks a jaw-dropping turnaround for hallucinogenic drugs. Even 10 years ago, they were effectively taboo in many academic fields and halls of power. But as the intellectual rationale behind the war on drugs has become increasingly untenable, hundreds of millions of dollars have been pumped into psychedelic pharmaceutical research.



US Moves to Protect All Species of Pangolin, World’s Most Trafficked Mammal

A Malaysian pangolin walks past cages containing 45 others as a wildlife officer watches in Kuala Lumpur August 8, 2002. (Reuters)
A Malaysian pangolin walks past cages containing 45 others as a wildlife officer watches in Kuala Lumpur August 8, 2002. (Reuters)
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US Moves to Protect All Species of Pangolin, World’s Most Trafficked Mammal

A Malaysian pangolin walks past cages containing 45 others as a wildlife officer watches in Kuala Lumpur August 8, 2002. (Reuters)
A Malaysian pangolin walks past cages containing 45 others as a wildlife officer watches in Kuala Lumpur August 8, 2002. (Reuters)

The United States on Monday moved to extend federal protections to all species of pangolins -- a step that would tighten trade restrictions and highlight the urgent conservation plight of the world's only scaly mammals.

Found in the forests, woodlands, and savannas of Africa and Asia, pangolins are small, nocturnal creatures known for their distinctive appearance, slow and peaceful demeanor, and habit of curling into a ball when threatened.

Often likened to a walking pinecone, they use long, sticky tongues to feast on ants and termites, give birth to a single pup each year -- and are the most heavily trafficked mammals on Earth. Their keratin scales are coveted in traditional medicine, and their meat is also considered a delicacy in some regions.

Despite steep population declines driven by poaching, habitat loss, and inbreeding, only one species -- Temminck's pangolin of Africa -- is currently protected under the US Endangered Species Act. Monday's proposal by the US Fish and Wildlife Service would extend that status to all eight known species.

In a statement, the agency said it intends to list the four Asian species -- Chinese, Indian, Sunda, and Philippine -- as well as the three other African species: white-bellied, black-bellied, and giant pangolins.

"I'm delighted the United States is doing its part to save these adorably odd creatures," said Sarah Uhlemann, international program director at the Center for Biological Diversity.

"Pangolins are on the razor's edge of extinction, and we need to completely shut down any US market for their scales. There's no good reason for anybody to ingest any part of a pangolin."

Pangolins are currently protected under the Convention on International Trade in Endangered Species of Wild Fauna and Flora (CITES), which prohibits international trade for commercial purposes and allows it only under exceptional circumstances.

Still, the illegal trade persists.

In April, Nigerian authorities seized nearly four tons of trafficked pangolin scales, representing the slaughter of some 2,000 animals. In November 2024, Indonesian officials intercepted another 1.2 tons.

US demand remains a factor. Between 2016 and 2020, border officials intercepted 76 shipments of pangolin parts, including scales and products marketed for traditional medicine, according to public data.