More Australian Towns Threatened by Massive Bushfire 

A CFA strike team is seen at a fire near Raglan in Victoria, Friday, February 23, 2024. (AAP)
A CFA strike team is seen at a fire near Raglan in Victoria, Friday, February 23, 2024. (AAP)
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More Australian Towns Threatened by Massive Bushfire 

A CFA strike team is seen at a fire near Raglan in Victoria, Friday, February 23, 2024. (AAP)
A CFA strike team is seen at a fire near Raglan in Victoria, Friday, February 23, 2024. (AAP)

Fresh evacuation warnings were issued on Friday for dozens of rural Australian towns as around 1,000 firefighters battled a bushfire in Victoria state which has destroyed properties, killed livestock and is threatening to spread through towns.

More than 2,000 people on Thursday fled from towns in Victoria's west after emergency evacuation orders were issued to leave while it was still safe and head east to the nearby regional hub of Ballarat, 95 km (59 miles) west of Melbourne.

Firefighters, supported by more than 50 aircraft, battled to contain the massive blaze on Friday. Roughly 11,000 hectares (110 square kms) have been burnt, authorities said.

"We are sadly hearing reports of property loss that are starting to come through," Victoria state Premier Jacinta Allan said during a press briefing.

"Given the active nature of the fire and the difficult terrain in the area, it is going to take some time to assess the full extent of the damage."

At least two schools have been closed and students in four have been relocated to other schools, while around 5,000 properties are without power across Victoria.

Stronger-than-expected winds are spreading fires faster and closer to towns as emergency crews urged residents to take shelter indoors if unable to leave.

A cold front off Australia's south coast moved overnight to the regions in the east battling bushfires, pushing temperatures down but strong winds continued to fan the wildfires.

"Unfortunately, those winds did not drop to where we thought they were going to be and that is what led the fire to accelerate where it did," said Jason Heffernan, chief officer of Victoria state fire department.

Emergency crews would begin taking stock of damages from Friday though early reports indicate significant losses of sheds and livestock as the fire spreads through several farms, Heffernan said. One home has been confirmed lost.



Blood Tests Allow 30-year Estimates of Women's Cardio Risks, New Study Says

A woman jogs in a park in Saint-Sebastien-sur-Loire near Nantes, France January 19, 2024. REUTERS/Stephane Mahe/File Photo Purchase Licensing Rights
A woman jogs in a park in Saint-Sebastien-sur-Loire near Nantes, France January 19, 2024. REUTERS/Stephane Mahe/File Photo Purchase Licensing Rights
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Blood Tests Allow 30-year Estimates of Women's Cardio Risks, New Study Says

A woman jogs in a park in Saint-Sebastien-sur-Loire near Nantes, France January 19, 2024. REUTERS/Stephane Mahe/File Photo Purchase Licensing Rights
A woman jogs in a park in Saint-Sebastien-sur-Loire near Nantes, France January 19, 2024. REUTERS/Stephane Mahe/File Photo Purchase Licensing Rights

Women’s heart disease risks and their need to start taking preventive medications should be evaluated when they are in their 30s rather than well after menopause as is now the practice, said researchers who published a study on Saturday.

Presenting the findings at the European Society of Cardiology annual meeting in London, they said the study showed for the first time that simple blood tests make it possible to estimate a woman’s risk of cardiovascular disease over the next three decades.

"This is good for patients first and foremost, but it is also important information for (manufacturers of) cholesterol lowering drugs, anti-inflammatory drugs, and lipoprotein(a)lowering drugs - the implications for therapy are broad," said study leader Dr. Paul Ridker of Brigham and Women’s Hospital in Boston, Reuters reported.

Current guidelines “suggest to physicians that women should generally not be considered for preventive therapies until their 60s and 70s. These new data... clearly demonstrate that our guidelines need to change,” Ridker said. “We must move beyond discussions of 5 or 10 year risk."

The 27,939 participants in the long-term Women’s Health Initiative study had blood tests between 1992 and 1995 for low density lipoprotein cholesterol (LDL-C or “bad cholesterol”), which are already a part of routine care.

They also had tests for high-sensitivity C-reactive protein (hsCRP) - a marker of blood vessel inflammation - and lipoprotein(a), a genetically determined type of fat.

Compared to risks in women with the lowest levels of each marker, risks for major cardiovascular events like heart attacks or strokes over the next 30 years were 36% higher in women with the highest levels of LDL-C, 70% higher in women with the highest levels of hsCRP, and 33% higher in those with the highest levels of lipoprotein(a).

Women in whom all three markers were in the highest range were 2.6 times more likely to have a major cardiovascular event and 3.7 times more likely to have a stroke over the next three decades, according to a report of the study in The New England Journal of Medicine published to coincide with the presentation at the meeting.

“The three biomarkers are fully independent of each other and tell us about different biologic issues each individual woman faces,” Ridker said.

“The therapies we might use in response to an elevation in each biomarker are markedly different, and physicians can now specifically target the individual person’s biologic problem.”

While drugs that lower LDL-C and hsCRP are widely available - including statins and certain pills for high blood pressure and heart failure - drugs that reduce lipoprotein(a) levels are still in development by companies, including Novartis , Amgen , Eli Lilly and London-based Silence Therapeutics.

In some cases, lifestyle changes such as exercising and quitting smoking can be helpful.

Most of the women in the study were white Americans, but the findings would likely “have even greater impact among Black and Hispanic women for whom there is even a higher prevalence of undetected and untreated inflammation,” Ridker said.

“This is a global problem,” he added. “We need universal screening for hsCRP ... and for lipoprotein(a), just as we already have universal screening for cholesterol.”