Moderna Says Next-generation COVID Vaccine Efficacy Non-inferior to Current Shot

Boxes containing the Moderna Covid-19 vaccine are prepared to be shipped at the McKesson distribution center in Olive Branch, Mississippi, on December 20, 2020. (AFP)
Boxes containing the Moderna Covid-19 vaccine are prepared to be shipped at the McKesson distribution center in Olive Branch, Mississippi, on December 20, 2020. (AFP)
TT

Moderna Says Next-generation COVID Vaccine Efficacy Non-inferior to Current Shot

Boxes containing the Moderna Covid-19 vaccine are prepared to be shipped at the McKesson distribution center in Olive Branch, Mississippi, on December 20, 2020. (AFP)
Boxes containing the Moderna Covid-19 vaccine are prepared to be shipped at the McKesson distribution center in Olive Branch, Mississippi, on December 20, 2020. (AFP)

Moderna said on Thursday its next-generation COVID-19 vaccine candidate showed it was not inferior in efficacy compared to its approved shot in a late-stage study.

The experimental vaccine, which met the main trial goal, was being tested in more than 11,000 people aged 12 years and older. The shot showed superior efficacy in adults than the current vaccine sold under the brand Spikevax.

Moderna had designed the next-generation vaccine to offer a longer shelf life and the ability to store and ship in refrigerators instead of freezers, potentially alleviating a major hurdle for its distribution, especially in developing countries, Reuters reported.

The new findings build on data released in March, which showed the vaccine had elicited a stronger immune response against both the Omicron BA.4/BA.5 variant and original strains of the coronavirus compared with Spikevax.

Moderna has been working on multiple new messenger RNA vaccines, including the recently approved RSV vaccine, mRESVIA, and other experimental shots, to tackle waning demand for COVID vaccines.

The company will present the clinical data at a conference, as well as engage with regulators on the next steps for the next-generation COVID vaccine.

The new COVID vaccine is also being tested as a combination shot with Moderna's flu shot.

On Monday, the company said the combination vaccine generated a stronger immune response in adults aged 50 and over in a late-stage trial when compared to separate shots.

The drugmaker hopes to launch the combination shot for the autumn respiratory disease season next year, Moderna President Stephen Hoge had then said.

"If not 2025, then 2026."



Riyadh Hosts International Chemistry Olympiad 2024

Riyadh hosts the 56th edition of the International Chemistry Olympiad 2024 (IChO 2024) from July 21 to 30. (SPA)
Riyadh hosts the 56th edition of the International Chemistry Olympiad 2024 (IChO 2024) from July 21 to 30. (SPA)
TT

Riyadh Hosts International Chemistry Olympiad 2024

Riyadh hosts the 56th edition of the International Chemistry Olympiad 2024 (IChO 2024) from July 21 to 30. (SPA)
Riyadh hosts the 56th edition of the International Chemistry Olympiad 2024 (IChO 2024) from July 21 to 30. (SPA)

Riyadh hosts the 56th edition of the International Chemistry Olympiad 2024 (IChO 2024) from July 21 to 30, the Saudi Press Agency said on Sunday.
The event is organized by the King Abdulaziz and his Companions Foundation for Giftedness and Creativity "Mawhiba”, in strategic partnership with the Ministry of Education and King Saud University (KSU), which will host the competition.
The IChO 2024, exclusively sponsored by Saudi Basic Industries Corporation (SABIC), will feature 333 students from 90 countries, with oversight, evaluation, and judging by 260 chemistry experts.
Students will compete for 10 honorary certificates, 110 bronze medals, 70 silver medals, and 35 gold medals. The final results will be announced on July 28 at 11 PM.
This annual scientific competition is the largest international chemistry contest for general education students.
Since its establishment in Prague, Czechoslovakia, in 1968, the competition has been held annually over ten days, with a different host country each year.
The Kingdom of Saudi Arabia participated as an observer in 2004 and 2005, then with students in 2006 and 2007. The Kingdom returned to participate as an observer in 2008, 2009, and 2010, and has since participated with students from 2011 up to present.
The Kingdom’s hosting of the IChO 2024 reflects the excellence of Saudi students on the international stage and enhances the Kingdom's status as a leading global destination in various scientific fields.