Nobel Prize in Medicine Honors Two Americans for Discovery of MicroRNA

Nobel Committee Secretary General Thomas Perlmann speaks to the media in front of a picture of this year's laureates Victor Ambros and Gary Ruvkum during the announcement of the winners of the 2024 Nobel Prize in Physiology or Medicine at the Karolinska Institute in Stockholm on October 7, 2024. (AFP)
Nobel Committee Secretary General Thomas Perlmann speaks to the media in front of a picture of this year's laureates Victor Ambros and Gary Ruvkum during the announcement of the winners of the 2024 Nobel Prize in Physiology or Medicine at the Karolinska Institute in Stockholm on October 7, 2024. (AFP)
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Nobel Prize in Medicine Honors Two Americans for Discovery of MicroRNA

Nobel Committee Secretary General Thomas Perlmann speaks to the media in front of a picture of this year's laureates Victor Ambros and Gary Ruvkum during the announcement of the winners of the 2024 Nobel Prize in Physiology or Medicine at the Karolinska Institute in Stockholm on October 7, 2024. (AFP)
Nobel Committee Secretary General Thomas Perlmann speaks to the media in front of a picture of this year's laureates Victor Ambros and Gary Ruvkum during the announcement of the winners of the 2024 Nobel Prize in Physiology or Medicine at the Karolinska Institute in Stockholm on October 7, 2024. (AFP)

The Nobel Prize in medicine was awarded Monday to Americans Victor Ambros and Gary Ruvkun for their discovery of microRNA, a fundamental principle governing how gene activity is regulated.

The Nobel Assembly said that their discovery is “proving to be fundamentally important for how organisms develop and function.”

Ambrose performed the research that led to his prize at Harvard University. He is currently a professor of natural science at the University of Massachusetts Medical School. Rackham’s research was performed at Massachusetts General Hospital and the Harvard Medical School, where he’s a professor of genetics, said Thomas Perlmann, Secretary-General of the Nobel Committee.

Last year, the Nobel Prize in Physiology or Medicine went to Hungarian-American Katalin Karikó and American Drew Weissman for discoveries that enabled the creation of mRNA vaccines against COVID-19 that were critical in slowing the pandemic.

The prize carries a cash award of 11 million Swedish kronor ($1 million) from a bequest left by the prize’s creator, Swedish inventor Alfred Nobel.

The announcement launched this year’s Nobel prizes award season.

Nobel announcements continue with the physics prize on Tuesday, chemistry on Wednesday and literature on Thursday. The Nobel Peace Prize will be announced Friday and the Nobel Memorial Prize in Economic Sciences on Oct. 14.

The laureates are invited to receive their awards at ceremonies on Dec. 10, the anniversary of Nobel’s death.



Tropical Storm Milton Forms in Gulf of Mexico and Could Intensify to Hurricane threatening Florida

This GOES-16 GeoColor satellite image taken at 4:50 p.m. EDT and provided by National Oceanic and Atmospheric Administration (NOAA) shows Tropical Storm Milton, center, off the coast of Mexico in the Gulf of Mexico, Saturday, Oct. 5, 2024. (NOAA via AP)
This GOES-16 GeoColor satellite image taken at 4:50 p.m. EDT and provided by National Oceanic and Atmospheric Administration (NOAA) shows Tropical Storm Milton, center, off the coast of Mexico in the Gulf of Mexico, Saturday, Oct. 5, 2024. (NOAA via AP)
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Tropical Storm Milton Forms in Gulf of Mexico and Could Intensify to Hurricane threatening Florida

This GOES-16 GeoColor satellite image taken at 4:50 p.m. EDT and provided by National Oceanic and Atmospheric Administration (NOAA) shows Tropical Storm Milton, center, off the coast of Mexico in the Gulf of Mexico, Saturday, Oct. 5, 2024. (NOAA via AP)
This GOES-16 GeoColor satellite image taken at 4:50 p.m. EDT and provided by National Oceanic and Atmospheric Administration (NOAA) shows Tropical Storm Milton, center, off the coast of Mexico in the Gulf of Mexico, Saturday, Oct. 5, 2024. (NOAA via AP)

A storm system that was brewing in the Gulf of Mexico strengthened into Tropical Storm Milton on Saturday and forecasters warned it could intensify into a hurricane and slam into the west coast of Florida later this week.

Tropical Storm Milton was about 355 miles (565 kilometers) west-northwest of Progreso, Mexico, and about 845 miles (1,360 kilometers) west-southwest of Tampa, Florida, with maximum sustained winds of 50 mph (80 kph) while heading east at 5 mph (8 kph), the National Hurricane Center in Miami said early Sunday, The AP reported.

“Milton moving slowly but expected to strengthen rapidly,” the center said, noting a “risk of life-threatening impacts increasing for portions of the Florida west coast.”

Florida Gov. Ron DeSantis declared a state of emergency in 35 counties ahead of the storm's potential landfall. Since many of those counties are still recovering from Hurricane Helene, DeSantis asked the Florida Division of Emergency Management and the Florida Department of Transportation to coordinate all available resources and personnel to supplement local communities as they expedite debris removal.

Though no coastal watches or warnings were in effect, the hurricane center said the Florida Peninsula, the Florida Keys, Mexico's Yucatan peninsula and the northwestern Bahamas should monitor the system’s progress.

The storm is forecast to strengthen and bring the risk of life-threatening impacts to parts of Florida, with hurricane and storm-surge watches likely in effect from Sunday. Parts of the state are expected to have heavy rainfall beginning that day, threatening flash, urban, and areal flooding, along with some river flooding.

“There is an increasing risk of life-threatening storm surge and wind impacts for portions of the west coast of the Florida Peninsula beginning late Tuesday or Wednesday. Residents in these areas should ensure they have their hurricane plan in place, follow any advice given by local officials, and check back for updates to the forecast,” the center said.

Meanwhile, Hurricane Kirk remained a Category 4 major hurricane about 1,345 miles (2,165 kilometers) west-southwest of the Azores with maximum sustained winds of 115 mph (185 kph) late Saturday night, the center said.

Large swells from the storm causing “life-threatening surf and rip current conditions” were affecting the Leeward Islands, Bermuda, the Greater Antilles, the Bahamas and the US. East Coast. The swells were expected to move north along the US East Coast and Canada's Atlantic Coast on Sunday and to the Azores on Monday, the center said.

Hurricane Leslie was moving northwest over the open Atlantic without posing a threat to land, forecasters said late Saturday.

The storm was located about 855 miles (1,375 kilometers) west of the southernmost Cabo Verde Islands with maximum sustained winds of 80 mph (128 kph). There were no coastal watches or warnings in effect.

The storms churned as rescuers in the US Southeast searched for people unaccounted for after Hurricane Helene struck last week, leaving behind a trail of death and catastrophic damage.