Nobel Prize in Medicine Honors Two Americans for Discovery of MicroRNA

Nobel Committee Secretary General Thomas Perlmann speaks to the media in front of a picture of this year's laureates Victor Ambros and Gary Ruvkum during the announcement of the winners of the 2024 Nobel Prize in Physiology or Medicine at the Karolinska Institute in Stockholm on October 7, 2024. (AFP)
Nobel Committee Secretary General Thomas Perlmann speaks to the media in front of a picture of this year's laureates Victor Ambros and Gary Ruvkum during the announcement of the winners of the 2024 Nobel Prize in Physiology or Medicine at the Karolinska Institute in Stockholm on October 7, 2024. (AFP)
TT

Nobel Prize in Medicine Honors Two Americans for Discovery of MicroRNA

Nobel Committee Secretary General Thomas Perlmann speaks to the media in front of a picture of this year's laureates Victor Ambros and Gary Ruvkum during the announcement of the winners of the 2024 Nobel Prize in Physiology or Medicine at the Karolinska Institute in Stockholm on October 7, 2024. (AFP)
Nobel Committee Secretary General Thomas Perlmann speaks to the media in front of a picture of this year's laureates Victor Ambros and Gary Ruvkum during the announcement of the winners of the 2024 Nobel Prize in Physiology or Medicine at the Karolinska Institute in Stockholm on October 7, 2024. (AFP)

The Nobel Prize in medicine was awarded Monday to Americans Victor Ambros and Gary Ruvkun for their discovery of microRNA, a fundamental principle governing how gene activity is regulated.

The Nobel Assembly said that their discovery is “proving to be fundamentally important for how organisms develop and function.”

Ambrose performed the research that led to his prize at Harvard University. He is currently a professor of natural science at the University of Massachusetts Medical School. Rackham’s research was performed at Massachusetts General Hospital and the Harvard Medical School, where he’s a professor of genetics, said Thomas Perlmann, Secretary-General of the Nobel Committee.

Last year, the Nobel Prize in Physiology or Medicine went to Hungarian-American Katalin Karikó and American Drew Weissman for discoveries that enabled the creation of mRNA vaccines against COVID-19 that were critical in slowing the pandemic.

The prize carries a cash award of 11 million Swedish kronor ($1 million) from a bequest left by the prize’s creator, Swedish inventor Alfred Nobel.

The announcement launched this year’s Nobel prizes award season.

Nobel announcements continue with the physics prize on Tuesday, chemistry on Wednesday and literature on Thursday. The Nobel Peace Prize will be announced Friday and the Nobel Memorial Prize in Economic Sciences on Oct. 14.

The laureates are invited to receive their awards at ceremonies on Dec. 10, the anniversary of Nobel’s death.



Strongest Winds in Over a Decade Could Increase Fire Risk to Southern California

FILE - Flags fly under heavy winds before sunset as a plume of smoke from the Franklin Fire rises over the ocean Tuesday, Dec. 10, 2024, in Malibu, Calif. (AP Photo/Damian Dovarganes,File)
FILE - Flags fly under heavy winds before sunset as a plume of smoke from the Franklin Fire rises over the ocean Tuesday, Dec. 10, 2024, in Malibu, Calif. (AP Photo/Damian Dovarganes,File)
TT

Strongest Winds in Over a Decade Could Increase Fire Risk to Southern California

FILE - Flags fly under heavy winds before sunset as a plume of smoke from the Franklin Fire rises over the ocean Tuesday, Dec. 10, 2024, in Malibu, Calif. (AP Photo/Damian Dovarganes,File)
FILE - Flags fly under heavy winds before sunset as a plume of smoke from the Franklin Fire rises over the ocean Tuesday, Dec. 10, 2024, in Malibu, Calif. (AP Photo/Damian Dovarganes,File)

The strongest winds in more than a decade could hit Southern California on Tuesday, potentially causing structural damage and bringing extreme fire risk to areas that haven't seen substantial rain in months.

Beginning Tuesday afternoon, the windstorm will affect Los Angeles and Ventura counties and peak in the early hours of Wednesday, when gusts could reach 80 mph (129 kph), the National Weather Service said Monday.

Isolated gusts could top 100 mph (160 kph) in mountains and foothills, The Associated Press reported.

The weather service warned of downed trees and knocked over big rigs, trailers, and motorhomes. Powerful offshore gusts will also bring dangerous conditions off the coasts of Orange County and LA, including Catalina Island, and potential delays and turbulence could arise at local airports.
Public safety power shutoffs are being considered for nearly 300,000 customers across the region, according to Southern California Edison’s website.

The upcoming winds will act as an “atmospheric blow-dryer” for vegetation, bringing a long period of fire risk that could extend into the more populated lower hills and valleys, according to Daniel Swain, a climate scientist with the University of California, Los Angeles and the National Center for Atmospheric Research.

“We really haven't seen a season as dry as this one follow a season as wet as the previous one,” Swain said during a Monday livestream. “All of that extra abundant growth of grass and vegetation followed immediately by a wind event of this magnitude while it's still so incredibly dry," elevates the risk.
Recent dry winds, including the notorious Santa Anas, have contributed to warmer-than-average temperatures in Southern California, where there’s been very little rain so far this season.
Southern California hasn’t seen more than 0.1 inches (0.25 centimeters) of rain since early May. Much of the region has fallen into moderate drought conditions, according to the U.S. Drought Monitor. Meanwhile, up north, there have been multiple drenching storms.
Areas where gusts could create extreme fire conditions include the charred footprint of last month’s wind-driven Franklin Fire, which damaged or destroyed 48 structures, mostly homes, in and around Malibu.
The blaze was one of nearly 8,000 wildfires that added up to scorch more than 1,560 square miles (more than 4,040 square kilometers) in the Golden State last year.
The last wind event of this magnitude occurred in November 2011, according to the NWS, during which more than 400,000 customers throughout LA County lost power, the Los Angeles Times reported. At night, normally bustling streets were dim and left without traffic signals.
Planned power shutoffs for the public's safety, if deemed necessary, are projected to happen Tuesday and Wednesday, according to Southern California Edison.
“The grid is built to withstand strong winds,” said Jeff Monford, a spokesperson for the utility. “The issue here is the possibility of debris becoming airborne and hitting wires ... or a tree coming down.”