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Weight-Loss Drugs May Lower Cancer Risk in People with Diabetes, a Study Suggests 

A box of Ozempic made by Novo Nordisk is seen at a pharmacy in London, Britain March 8, 2024. (Reuters) 
A box of Ozempic made by Novo Nordisk is seen at a pharmacy in London, Britain March 8, 2024. (Reuters) 
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Weight-Loss Drugs May Lower Cancer Risk in People with Diabetes, a Study Suggests 

A box of Ozempic made by Novo Nordisk is seen at a pharmacy in London, Britain March 8, 2024. (Reuters) 
A box of Ozempic made by Novo Nordisk is seen at a pharmacy in London, Britain March 8, 2024. (Reuters) 

Excess body weight can raise the risk of certain cancers, leading researchers to wonder whether blockbuster drugs like Wegovy, Ozempic and Zepbound could play a role in cancer prevention.

Now, a study of 170,000 patient records suggests there's a slightly lower risk of obesity-related cancers in US adults with diabetes who took these popular medications compared to those who took another class of diabetes drug not associated with weight loss.

This type of study can't prove cause and effect, but the findings hint at a connection worth exploring. More than a dozen cancers are associated with obesity.

“This is a call to scientists and clinical investigators to do more work in this area to really prove or disprove this,” said Dr. Ernest Hawk of MD Anderson Cancer Center in Houston, who was not involved in the study.

The findings were released Thursday by the American Society of Clinical Oncology and will be discussed at its annual meeting in Chicago. The study, funded by the National Institutes of Health, was led by Lucas Mavromatis, a medical student at New York University’s Grossman School of Medicine.

“Chronic disease and chronic disease prevention are some of my passions,” said Mavromatis, a former research fellow with an NIH training program.

GLP-1 receptor agonists are injections used to treat diabetes, and some are also approved to treat obesity. They work by mimicking hormones in the gut and the brain to regulate appetite and feelings of fullness. They don't work for everyone and can produce side effects that include nausea and stomach pain.

In the study, researchers analyzed data from 43 US health systems to compare two groups: people with obesity and diabetes who took GLP-1 drugs and other people with the same conditions who took diabetes drugs like sitagliptin. The two groups were equal in size and matched for other characteristics.

After four years, those who took GLP-1 drugs had a 7% lower risk of developing an obesity-related cancer and an 8% lower risk of death from any cause compared to those who took the other type of diabetes drug. There were 2,501 new cases of obesity-related cancer in the GLP-1 group compared to 2,671 cases in the other group.

The effect was evident in women, but not statistically significant in men. The study couldn't explain that difference, but Mavromatis noted that differences in blood drug concentration, weight loss, metabolism or hormones could be at play.

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Varieties

Heavy Rains Drench Southern California, Spawn Flash Flooding, Mud Flows

A car sits buried in mud after flooding Wednesday, Dec. 24, 2025, in Wrightwood, Calif. (AP)
A car sits buried in mud after flooding Wednesday, Dec. 24, 2025, in Wrightwood, Calif. (AP)
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Heavy Rains Drench Southern California, Spawn Flash Flooding, Mud Flows

A car sits buried in mud after flooding Wednesday, Dec. 24, 2025, in Wrightwood, Calif. (AP)
A car sits buried in mud after flooding Wednesday, Dec. 24, 2025, in Wrightwood, Calif. (AP)

Torrential rains unleashed widespread flash flooding and mud flows across Southern California on Wednesday, as authorities warned motorists to stay off roads while urging residents in flood zones to evacuate or shelter in place.

In the rain-soaked mountain resort of Wrightwood, east of Los Angeles, emergency crews spent much of the day answering dozens of rescue calls and pulling drivers to safety from submerged vehicles, San Bernardino County Fire Department spokesperson Christopher Prater said.

No casualties were reported as ‌of Wednesday night, according ‌to Prater.

Aerial video footage posted online by the fire department ‌showed ⁠rivers of ‌mud coursing through inundated cabin neighborhoods.

Downpours measuring an inch (2.54 cm) or more of rain an hour in some areas were spawned by the region's latest atmospheric storm, a vast airborne current of dense moisture siphoned from the Pacific and swept inland over the greater Los Angeles area.

The Christmas Eve storm was expected to persist into Friday, posing unsafe driving conditions during what would normally be a busy holiday travel period, according to the US National Weather Service.

"Life-threatening" storm conditions ⁠were expected to persist through Christmas Day over Southern California, "where widespread flash flooding is underway," the weather service said.

A flash-flood ‌warning was posted across much of Los Angeles County until ‍6 p.m. PST, urging motorists: "Do not ‍attempt to travel unless you are fleeing an area, subject to flooding or under ‍an evacuation order."

Los Angeles city officials urged residents to heed evacuation orders issued for about 130 homes considered especially vulnerable to mudslides and debris flows in areas where last year's wildfires ravaged the community of Pacific Palisades.

The San Bernardino County Sheriff's Department issued an evacuation warning for Wrightwood earlier in the day, but elevated the advisory to a shelter-in-place order as flood conditions worsened. The Angeles Crest Highway, a major traffic route through the San ⁠Gabriel Mountains, was closed in two stretches due to flooding

Wednesday's heavy rainfall was accompanied by strong, gusty winds that officials said were downing trees and power lines. In upper elevations of the Sierra mountains, the storm was expected to dump heavy snow.

NWS meteorologist Ariel Cohen said 4 to 8 inches of rain had fallen in some foothill areas by 9 a.m. PST, and the Los Angeles City News Service reported numerous rockslides in the mountains. Forecasts called for more than a foot (30.48 cm) of rain falling over some lower-terrain mountain areas by week's end.

Forecasters even issued a rare tornado warning for a small portion of east-central Los Angeles County due to heavy thunderstorm activity over the community of Alhambra.

As of Wednesday night, ‌rainfall over the region had subsided, but a second wave of the storm system was due to hit on Thursday, forecasters said.

Varieties

China's LandSpace Hopes to Complete Rocket Recovery in Mid-2026

Zhuque-3 rocket by China’s private rocket firm LandSpace, takes off from the Jiuquan Satellite Launch Center, China, December 3, 2025, in this screengrab taken from handout drone footage provided by LandSpace. LandSpace/Handout via REUTERS
Zhuque-3 rocket by China’s private rocket firm LandSpace, takes off from the Jiuquan Satellite Launch Center, China, December 3, 2025, in this screengrab taken from handout drone footage provided by LandSpace. LandSpace/Handout via REUTERS
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China's LandSpace Hopes to Complete Rocket Recovery in Mid-2026

Zhuque-3 rocket by China’s private rocket firm LandSpace, takes off from the Jiuquan Satellite Launch Center, China, December 3, 2025, in this screengrab taken from handout drone footage provided by LandSpace. LandSpace/Handout via REUTERS
Zhuque-3 rocket by China’s private rocket firm LandSpace, takes off from the Jiuquan Satellite Launch Center, China, December 3, 2025, in this screengrab taken from handout drone footage provided by LandSpace. LandSpace/Handout via REUTERS

Chinese rocket developer LandSpace plans to successfully recover a reusable booster in mid-2026, a company executive said in an interview, underscoring the Beijing-based firm's ambition to become China's answer to SpaceX.

The ability to return, recover, and reuse a rocket's engine-packed first stage, or booster, after launch is crucial to reducing costs and making it easier for countries to send satellites into orbit, and to turn space exploration into a commercially viable business similar to civil aviation, Reuters reported.

Earlier this month, privately-owned LandSpace ‌became the first ‌Chinese entity to conduct a full reusable rocket ‌test, when ⁠Zhuque-3 ​blasted off ‌from a remote area in northwest China for its maiden flight, drawing comparisons to US aerospace giant SpaceX.

SECOND ATTEMPT PLANNED

While LandSpace failed to complete the crucial final step of landing and recovering the rocket's engine-packed booster, it hopes to clear this challenge in mid-2026 with a second test flight, Zhuque-3 deputy chief designer Dong Kai told Chinese podcast Tech Early Know in an interview published on Tuesday.

"If the second flight's recovery (stage) succeeds, we ⁠plan that on the fourth flight we will use a reused first stage to launch," Dong said.

So far, ‌the only company that has mastered reusable rocket technology is ‍SpaceX, founded by the world's richest ‍person Elon Musk. SpaceX's Falcon 9 launches around 150 times a year, or roughly ‍three times per week, with its booster reused dozens of times if necessary.

Musk said in October that LandSpace's Zhuque-3 design could allow it to beat the Falcon 9, but went on to state that the Chinese challenger's launch cadence would take more than five years to ​reach that of SpaceX's workhorse model, at which point the US firm would have transitioned to its heavier, new-generation model Starship and "doing over ⁠100 times the annual payload to orbit of Falcon".

INITIAL PUBLIC OFFERING

LandSpace's Dong said that, while the company was already building an engine for a future Starship-like model, he was not optimistic that in five years Falcon 9's work rate could be surpassed, noting that all rocket models in China combined this year totalled only around 100 launches.

"It's very difficult for a single company to reach that kind of frequency. It requires the support of an entire ecosystem," Dong said, adding that LandSpace had 10 launches planned next year for all its models.

Other executives have previously said that the financial cost of a high-frequency testing and launch regimen was crucial to SpaceX's success, and that LandSpace's only ‌hope of amassing enough funds to sustain a similar programme would be by tapping China's capital markets, pointing to plans for an initial public offering next year.

 

 

Varieties

Russia Plans a Nuclear Power Plant on the Moon within a Decade

November's full moon, also known as Beaver Moon, rises over Fort-de-France in the French overseas island of Martinique, on November 5, 2025. (AFP)
November's full moon, also known as Beaver Moon, rises over Fort-de-France in the French overseas island of Martinique, on November 5, 2025. (AFP)
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Russia Plans a Nuclear Power Plant on the Moon within a Decade

November's full moon, also known as Beaver Moon, rises over Fort-de-France in the French overseas island of Martinique, on November 5, 2025. (AFP)
November's full moon, also known as Beaver Moon, rises over Fort-de-France in the French overseas island of Martinique, on November 5, 2025. (AFP)

Russia plans to put ​a nuclear power plant on the moon in the next decade to supply its lunar space program and a joint Russian-Chinese research station as major powers rush to explore the earth's only natural satellite.

Ever since Soviet cosmonaut Yuri Gagarin became the first human to go into space in 1961, Russia has prided itself as ‌a leading power in ‌space exploration, but in recent ‌decades ⁠it ​has fallen ‌behind the United States and increasingly China.

Russia's ambitions suffered a massive blow in August 2023 when its unmanned Luna-25 mission smashed into the surface of the moon while attempting to land, and Elon Musk has revolutionized the launch of space vehicles - once a Russian specialty.

Russia's state space corporation, Roscosmos, ⁠said in a statement that it planned to build a lunar power ‌plant by 2036 and signed a contract ‍with the Lavochkin Association ‍aerospace company to do it.

Roscosmos said the purpose of ‍the plant was to power Russia's lunar program, including rovers, an observatory and the infrastructure of the joint Russian-Chinese International Lunar Research Station.

"The project is an important step towards the creation of ​a permanently functioning scientific lunar station and the transition from one-time missions to a long-term lunar exploration program," ⁠Roscosmos said.

Roscosmos did not say explicitly that the plant would be nuclear but it said the participants included Russian state nuclear corporation Rosatom and the Kurchatov Institute, Russia's leading nuclear research institute.

The head of Roscosmos, Dmitry Bakanov, said in June that one of the corporation's aims was to put a nuclear power plant on the moon and to explore Venus, known as earth's "sister" planet.

The moon, which is 384,400 km (238,855 miles) from our planet, moderates the earth's wobble ‌on its axis, which ensures a more stable climate. It also causes tides in the world's oceans.