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Encouraging Trial Results for AstraZeneca's New Weight-Loss Pill

The logo for AstraZeneca is seen outside its North America headquarters in Wilmington, Delaware, US, March 22, 2021. (Reuters)
The logo for AstraZeneca is seen outside its North America headquarters in Wilmington, Delaware, US, March 22, 2021. (Reuters)
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Encouraging Trial Results for AstraZeneca's New Weight-Loss Pill

The logo for AstraZeneca is seen outside its North America headquarters in Wilmington, Delaware, US, March 22, 2021. (Reuters)
The logo for AstraZeneca is seen outside its North America headquarters in Wilmington, Delaware, US, March 22, 2021. (Reuters)

A new pill developed by the British pharma firm AstraZeneca appears to help people lose a similar amount of weight to other GLP-1 oral drugs, trial results showed Monday.

If confirmed by further research, the pill could mark AstraZeneca's entrance into the massively lucrative weight-loss drug market currently dominated by Denmark's Novo Nordisk and American giant Eli Lilly.

The astronomical popularity of the appetite suppressing injectable drugs called GLP-1 agonists has kicked off a race to produce tablet versions that easier to take.

AstraZeneca's new pill, called elecoglipron, resulted in weight loss "comparable to that reported for other oral" GLP-1 drugs, according to phase 2 trial results published in the Lancet medical journal.

Side effects recorded during the randomized trial, which had 310 participants, were also similar to those seen for other GLP-1 pills, with nausea being the most common.

For overweight or obese adults without diabetes, the pill resulted in "average weight reductions of up to 10.5 percent at 26 weeks and 11.8 percent at 36 weeks in the highest-dose group," said Marie Spreckley of the University of Cambridge.

But the weight management researcher -- who was not involved in the study -- emphasized the phase 2 trial was not mainly designed to compare the pill to other anti-obesity drugs.

"Larger and longer phase 3 trials will therefore be needed to confirm the durability of these effects, establish longer-term safety and tolerability, and determine its place within the growing range of obesity and diabetes treatments," she explained.

AstraZeneca will face stiff competition -- Novo Nordisk and Eli Lilly have already developed pill versions of their hugely successful drugs.

The oral form of Eli Lilly's popular Mounjaro GLP-1 drug was approved in April in the United States, where it is sold under the brand name Foundayo.

The pill version of Novo Nordisk's blockbuster drug Wegovy is already available in the US and was given the green light by European Union health authorities last month.

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Corgis Race, Bark and Sniff Their Way to Glory at a Growing International Race

Corgis race during the Corgi Race Vilnius 2026 event in Vilnius, Lithuania, Saturday, Aug. 15, 2026. (AP)
Corgis race during the Corgi Race Vilnius 2026 event in Vilnius, Lithuania, Saturday, Aug. 15, 2026. (AP)
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Corgis Race, Bark and Sniff Their Way to Glory at a Growing International Race

Corgis race during the Corgi Race Vilnius 2026 event in Vilnius, Lithuania, Saturday, Aug. 15, 2026. (AP)
Corgis race during the Corgi Race Vilnius 2026 event in Vilnius, Lithuania, Saturday, Aug. 15, 2026. (AP)

It's not all about short-legged speed when 150 corgis gather for an international race celebrating the little dogs. There's a costume parade, the "smartest nose," and — of course — the loudest bark.

The fifth Corgi Race Vilnius drew dogs and their owners to the Lithuanian capital's Vingis park on Saturday for what organizers said was the biggest edition yet. There were competitors from Lithuania, Latvia, Poland, Estonia, Germany, Ukraine, the Czech Republic, the United States and Britain — the country most closely associated with the breed, famously a favorite of the late Queen Elizabeth II.

“In the first year, we gathered 40 corgis from one city. This year, it’s 150 from nine countries, and for the first time we have a participant from the place where the breed originated,” organizer Edvinas Miskas said.

“We call Vilnius the European capital of corgis, and when people from the breed’s homeland start coming to us rather than the other way around, that title begins to sound a little more serious.”

Ninety-four dogs took part in the main running event, competing in qualifiers, semifinals and the final.

In the final, which pitted corgis against each other over 25 meters (82 feet), the winner was American competitor GG, short for Gustave the Girl Dog. Another US entrant, Mr. Corgington, finished a close second. Lithuania's own Moka, a two-time former champion, was third.

But much of the program dispensed with speed to explore the other skills of the dogs and their owners.

There was a costume parade featuring 38 corgis in diverse outfits including a dinosaur suit, a dress and doggy sports gear. Amigo swept both the four-judge jury and the public Facebook vote for a flawless costume entry with a knight-like look.

In the “smartest nose” challenge, dogs searched for hidden treats. Latvian corgis Tora and Rusty shared the win.

And then there was the loudest bark competition. The first British competitor, 12-year-old Pembroke Welsh corgi Duke from Sedbergh in northwest England, didn't participate in the main race because of his stately age but was a hopeful in the barking stakes after, as his owner put it, training for his whole life.

It was Mr. Corgington who won the loudest bark contest, though.

He was one of the most traveled competitors. The final race offered him a rematch after he finished second against GG at a major race at Emerald Downs in Auburn, Washington — her second consecutive win there.

Half of the corgis registered in Vilnius this year were taking part for the first time. But six veterans — costume winner Amigo, Foksas, Foksis, Madeira, Bulka and Dziugas — have attended every edition.

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Belgium’s Biggest Wildfire on Record Heads Towards Germany

This aerial photograph shows a wildfire burning in the Hautes Fagnes (High Fens) nature reserve in Waimes on August 15, 2026. (AFP)
This aerial photograph shows a wildfire burning in the Hautes Fagnes (High Fens) nature reserve in Waimes on August 15, 2026. (AFP)
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Belgium’s Biggest Wildfire on Record Heads Towards Germany

This aerial photograph shows a wildfire burning in the Hautes Fagnes (High Fens) nature reserve in Waimes on August 15, 2026. (AFP)
This aerial photograph shows a wildfire burning in the Hautes Fagnes (High Fens) nature reserve in Waimes on August 15, 2026. (AFP)

Firefighters worked through the night to battle Belgium's biggest wildfire on record, which by Sunday morning had burned 3,000 hectares of land and was heading towards the German border, local authorities said.

The blaze in the High Fens, a nature reserve in the east of the country, has been burning since Friday and firefighters from across Belgium and neighboring Germany and Luxembourg have sought ‌to contain it, ‌as have the army and ‌farmers.

Responders ⁠on Sunday were ⁠focused on the front line of the fire moving towards Germany and were hopeful that cooler, more humid weather would support efforts to contain it, Stephanie Ernoux, spokesperson for the administration of the Belgian region of Wallonia, told Reuters.

The fire is ⁠more than double the size of ‌a blaze in ‌2011 that burned close to 1,400 hectares, data from the ‌European Forest Fire Information System showed.

The EU deployed ‌three helicopters and two water bomber aircraft from around Europe on Saturday after Belgium requested emergency reinforcements.

Local authorities said the defensive line protecting evacuated villages from the fire ‌was holding on Sunday, though residents who had been evacuated on Saturday were ⁠told ⁠they should not yet return to their homes.

"No homes have been affected at this stage, although the fire remains close and smoke levels are significant," the office of the governor of Liege said in an update.

The blaze ignited as European countries including Belgium suffered their fifth heatwave of the summer this week.

Scientists say that human-caused climate change has increased the likelihood of the hot and dry conditions that allow wildfires to spread faster and burn longer.

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Firefighters Battle Second Day of Blaze on Greek Island

A burnt vehicle after a fire that broke out in the summer resort of Siviri, Chalkidiki, northern Greece, 14 August 2026. (EPA)
A burnt vehicle after a fire that broke out in the summer resort of Siviri, Chalkidiki, northern Greece, 14 August 2026. (EPA)
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Firefighters Battle Second Day of Blaze on Greek Island

A burnt vehicle after a fire that broke out in the summer resort of Siviri, Chalkidiki, northern Greece, 14 August 2026. (EPA)
A burnt vehicle after a fire that broke out in the summer resort of Siviri, Chalkidiki, northern Greece, 14 August 2026. (EPA)

Firefighters battled for a second day on Sunday to contain a forest fire on the Greek Aegean island of Skyros, as the local mayor voiced hope it could soon be brought under control.

"Within the day I believe the fire will be fully extinguished," Skyros mayor Kyriakos Antonopoulos told state TV ERT.

The fire, which broke out on Saturday, prompted the evacuation of two small communities, but Antonopoulos said no inhabited areas were under threat on Sunday.

Reinforcements to the island of some 3,000 have been rushed in from neighboring areas.

After largely escaping the heatwave temperatures that blanketed much of Europe earlier this summer, Greece has been hit with several major wildfires since late July, fueled by unusually strong winds.

Five firefighters have died so far, including a Danish pilot killed in a mid-air collision between two Bell helicopters while battling a blaze near Athens earlier this month.

There was another scare last week when about 500 tourists were evacuated from beaches on the Halkidiki peninsula in northern Greece as a forest fire threatened two popular resorts.

Some 20,000 hectares of forest and agricultural land have burned this year in major fires near Athens and on the islands of Crete and Paros.

Greece is hit by wildfires every year. Experts say the risk is growing because of human-fueled climate change, which has made droughts and other extreme weather events more severe.