Iran’s Supreme Leader Opens Door to Negotiations with US over Tehran’s Nuclear Program

A handout photo made available by the supreme leader office shows Iranian Supreme Leader Ali Khamenei (L) speaking as Iranian President Masoud Pezeshkian looks on, during a meeting with the new Iranian government in Tehran, Iran, 27 August 2024. (EPA/Iranian Supreme Leader Office Handout)
A handout photo made available by the supreme leader office shows Iranian Supreme Leader Ali Khamenei (L) speaking as Iranian President Masoud Pezeshkian looks on, during a meeting with the new Iranian government in Tehran, Iran, 27 August 2024. (EPA/Iranian Supreme Leader Office Handout)
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Iran’s Supreme Leader Opens Door to Negotiations with US over Tehran’s Nuclear Program

A handout photo made available by the supreme leader office shows Iranian Supreme Leader Ali Khamenei (L) speaking as Iranian President Masoud Pezeshkian looks on, during a meeting with the new Iranian government in Tehran, Iran, 27 August 2024. (EPA/Iranian Supreme Leader Office Handout)
A handout photo made available by the supreme leader office shows Iranian Supreme Leader Ali Khamenei (L) speaking as Iranian President Masoud Pezeshkian looks on, during a meeting with the new Iranian government in Tehran, Iran, 27 August 2024. (EPA/Iranian Supreme Leader Office Handout)

Iran's supreme leader opened the door Tuesday to renewed negotiations with the United States over his country's rapidly advancing nuclear program, telling its civilian government there was “no harm" in engaging with its “enemy.”

Ali Khamenei's remarks set clear red lines for any talks taking place under the government of reformist President Masoud Pezeshkian and renewed his warnings that Washington wasn't to be trusted.

But his comments mirror those around the time of Iran's 2015 nuclear deal with world powers, which saw Tehran's nuclear program greatly curtailed in exchange for the lifting of economic sanctions. Yet it remains unclear just how much room Pezeshkian will have to maneuver, particularly as tensions remain high in the wider Middle East over the Israel-Hamas war and as the US prepares for a presidential election in November.

“This does not mean that we cannot interact with the same enemy in certain situations,” Khamenei said, according to a transcript on his official website. "There is no harm in that, but do not place your hopes in them.”

Khamenei, who has the final say on all state matters, also warned Pezeshkian's Cabinet, “Do not trust the enemy.”

Khamenei, 85, has occasionally urged talks or dismissed them with Washington after then-President Donald Trump unilaterally withdrew the United States from the deal in 2018.

There have been indirect talks between Iran and the US in recent years mediated by Oman and Qatar, two of the United States' Middle East interlocutors when it comes to Iran. Khamenei's remarks came a day after Qatar's prime minister visited the country.

Asked for comment, the US State Department told The Associated Press: “We will judge Iran’s leadership by their actions, not their words.”

“We have long said that we ultimately view diplomacy as the best way to achieve an effective, sustainable solution with regard to Iran’s nuclear program,” it said. “However, we are far away from anything like that right now given Iran’s escalations across the board, including its nuclear escalations and its failure to cooperate" with the International Atomic Energy Agency, the United Nations nuclear watchdog.

“If Iran wants to demonstrate seriousness or a new approach, they should stop nuclear escalations and start meaningfully cooperating with the IAEA,” it said.

Since the deal's collapse, Iran has abandoned all limits that the deal put on its program, and enriches uranium to up to 60% purity — near weapons-grade levels of 90%.

Surveillance cameras installed by the IAEA have been disrupted, while Iran has barred some of the Vienna-based agency’s most experienced inspectors. Iranian officials also have increasingly threatened that they could pursue atomic weapons.

Meanwhile, tensions between Iran and Israel have hit a new high during the Israel-Hamas war in the Gaza Strip. Tehran launched an unprecedented drone-and-missile attack on Israel in April after years of a shadow war between the two countries reached a climax with Israel’s apparent attack on an Iranian consular building in Syria that killed two Iranian generals and others.

The assassination in Tehran of Hamas leader Ismail Haniyeh also prompted Iran to threaten to retaliate against Israel.

Pezeshkian, a former lawmaker who won the presidency after a May helicopter crash killed hard-line President Ebrahim Raisi, campaigned in part on a promise to reengage the West with negotiations.

Khamenei's remarks as Iran's paramount leader could provide him with the political cover to do so. Pezeshkian's new foreign minister, Abbas Araghchi, was deeply involved in negotiations on the 2015 deal.

“After doing everything we can, a tactical retreat might sometimes be necessary, but we should not abandon our goals or opinions at the first sign of difficulty,” Khameini also said Tuesday, the second time in recent days he's referred to a “tactical retreat” amid the tensions.

However, it's not just Iran that's facing a new presidency. The US will hold a presidential election on Nov. 5, with Vice President Kamala Harris and Trump as the leading candidates. Iran has been concerned about Trump’s return to power.

While the US engaged in indirect talks with Iran under President Joe Biden, it remains unclear how that would carry over to a possible Harris administration. Harris, in a speech to the Democratic National Convention last week, said: “I will never hesitate to take whatever action is necessary to defend our forces and our interests against Iran and Iran-backed terrorists.”

The RANE Network, a risk-intelligence firm, said if Harris wins, “the likelihood of a deal will rise as the Israel-Hamas war winds down.”

“Once negotiations begin, Iran will likely demand more protections regarding a potential US withdrawal from a new deal after the United States walked away from the previous deal in 2018,” RANE said in an analysis Tuesday.

“Because of concerns about the sustainability of any new deal, Iran is also less likely to offer as many nuclear concessions, like the dismantling of more advanced centrifuges, since Iran would want to be able to spin up its nuclear program as fast as possible in the event of another US exit from the new deal.”

Tuesday's meeting between Khamenei and Pezeshkian's Cabinet included an appearance by former Foreign Minister Mohammad Javad Zarif, who helped Iran reach the 2015 deal. After the meeting, Zarif said in an online message that he would continue to serve as a vice president in Pezeshkian's administration after earlier publicly resigning over the makeup of the Cabinet.



Turkish FM to Attend Trump’s Board of Peace Meeting in Washington, Italy as ‘Observer’ 

28 November 2025, Berlin: Turkish Foreign Minister Hakan Fidan during a joint press conference with German Foreign Minister Wadephul. (dpa)
28 November 2025, Berlin: Turkish Foreign Minister Hakan Fidan during a joint press conference with German Foreign Minister Wadephul. (dpa)
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Turkish FM to Attend Trump’s Board of Peace Meeting in Washington, Italy as ‘Observer’ 

28 November 2025, Berlin: Turkish Foreign Minister Hakan Fidan during a joint press conference with German Foreign Minister Wadephul. (dpa)
28 November 2025, Berlin: Turkish Foreign Minister Hakan Fidan during a joint press conference with German Foreign Minister Wadephul. (dpa)

‌Turkish Foreign Minister Hakan Fidan will travel to Washington in lieu of President Recep Tayyip Erdogan for the inaugural meeting of US President Donald Trump's "Board of Peace" on Thursday, the foreign ministry said on Wednesday.

A Turkish diplomatic source told Reuters ‌that Fidan, during the ‌talks, would call ‌for ⁠determined steps to ⁠resolve the Palestinian issue and emphasize that Israel must end actions to hinder the flow of aid into Gaza and stop its ceasefire violations.

Fidan ⁠will also reiterate Türkiye's ‌readiness ‌to contribute to Gaza's reconstruction and its ‌desire to help protect Palestinians ‌and ensure their security, the source said.

He will also call for urgent action against Israel's "illegal ‌settlement activities and settler violence in the West Bank", ⁠the ⁠source added.

According to a readout from Erdogan's office, the president separately told reporters on Wednesday that he hoped the Board of Peace would help achieve "the lasting stability, ceasefire, and eventually peace that Gaza has longed for", and would focus on bringing about a two-state solution.

The board, of which Trump is the chairman, was initially designed to oversee the Gaza truce and the territory's reconstruction after the war between Hamas and Israel.

Meanwhile, Italy will be present at the meeting as an "observer", Italian Foreign Minister Antonio Tajani said Wednesday.

"I will go to Washington to represent Italy as an observer to this first meeting of the Board of Peace, to be present when talks occur and decisions are made for the reconstruction of Gaza and the future of Palestine," Tajani said according to ANSA news agency.

Italy cannot be present as anything more than an observer as the country's constitutional rules do not allow it to join an organization led by a single foreign leader.

But Tajani said it was key for Rome to be "at the forefront, listening to what is being done".

Since Trump launched the Board of Peace at the World Economic Forum in Davos in January, at least 19 countries have signed its founding charter.


Energy Secretary: US to Stop Iran's Nuclear Ambitions 'One Way or the Other'

US Secretary of Energy Chris Wright speaks during a press conference after a meeting with Venezuela's acting president Delcy Rodriguez at the Miraflores Presidential Palace in Caracas on February 11, 2026. (Photo by Juan BARRETO / AFP)
US Secretary of Energy Chris Wright speaks during a press conference after a meeting with Venezuela's acting president Delcy Rodriguez at the Miraflores Presidential Palace in Caracas on February 11, 2026. (Photo by Juan BARRETO / AFP)
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Energy Secretary: US to Stop Iran's Nuclear Ambitions 'One Way or the Other'

US Secretary of Energy Chris Wright speaks during a press conference after a meeting with Venezuela's acting president Delcy Rodriguez at the Miraflores Presidential Palace in Caracas on February 11, 2026. (Photo by Juan BARRETO / AFP)
US Secretary of Energy Chris Wright speaks during a press conference after a meeting with Venezuela's acting president Delcy Rodriguez at the Miraflores Presidential Palace in Caracas on February 11, 2026. (Photo by Juan BARRETO / AFP)

The United States will deter Iran from acquiring nuclear weapons "one way or the other", US Energy Secretary Chris Wright warned on Wednesday.

"They've been very clear about what they would do with nuclear weapons. It's entirely unacceptable," Wright told reporters in Paris on the sidelines of meetings of the International Energy Agency.

"So one way or the other, we are going to end, deter Iran's march towards a nuclear weapon," Wright said.

US and Iranian officials held talks in Geneva on Tuesday aimed at averting the possibility of US military intervention to curb Tehran's nuclear program.

Iran said following the talks that they had agreed on "guiding principles" for a deal to avoid conflict.

US Vice President JD Vance, however, said Tehran had not yet acknowledged all of Washington's red lines.


Iran, Russia to Conduct Joint Drills in the Sea of Oman 

This handout photo released by Iran's Revolutionary Guards Corps (IRGC)'s official website Sepanews on February 17, 2026, shows boats maneuvering around a tanker vessel during a military exercise by members of the IRGC and navy in the Strait of Hormuz. (Sepahnews / AFP)
This handout photo released by Iran's Revolutionary Guards Corps (IRGC)'s official website Sepanews on February 17, 2026, shows boats maneuvering around a tanker vessel during a military exercise by members of the IRGC and navy in the Strait of Hormuz. (Sepahnews / AFP)
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Iran, Russia to Conduct Joint Drills in the Sea of Oman 

This handout photo released by Iran's Revolutionary Guards Corps (IRGC)'s official website Sepanews on February 17, 2026, shows boats maneuvering around a tanker vessel during a military exercise by members of the IRGC and navy in the Strait of Hormuz. (Sepahnews / AFP)
This handout photo released by Iran's Revolutionary Guards Corps (IRGC)'s official website Sepanews on February 17, 2026, shows boats maneuvering around a tanker vessel during a military exercise by members of the IRGC and navy in the Strait of Hormuz. (Sepahnews / AFP)

Iran and Russia will conduct naval maneuvers in the Sea of Oman on Thursday, following the latest round of talks between Tehran and Washington in Geneva, Iranian media reported.

On Monday, the Revolutionary Guards, the ideological arm of Iran's military, also launched exercises in the strategic Strait of Hormuz, a challenge to US naval forces deployed in the region.

"The joint naval exercise of Iran and Russia will take place tomorrow (Thursday) in the Sea of Oman and in the northern Indian Ocean," the ISNA agency reported, citing drill spokesman, Rear Admiral Hassan Maghsoudloo.

"The aim is to strengthen maritime security and to deepen relations between the navies of the two countries," he said, without specifying the duration of the drill.

The war games come as Iran struck an upbeat tone following the second round of Oman-mediated negotiations in Geneva on Tuesday.

Previous talks between the two foes collapsed following the unprecedented Israeli strike on Iran in June 2025, which sparked a 12-day war that the United States briefly joined.

US President Donald Trump has deployed a significant naval force in the region, which he has described as an "armada."

Iranian officials have repeatedly threatened to block the Strait of Hormuz, particularly during periods of tension with the United States, but it has never been closed.

A key passageway for global shipments of oil and liquefied natural gas, the Strait of Hormuz has been the scene of several incidents in the past and has returned to the spotlight as pressure has ratcheted amid the US-Iran talks.

Iran announced on Tuesday that it would partially close it for a few hours for "security" reasons during its own drills in the strait.