Iran’s Supreme Leader Rejects Direct Nuclear Talks with US as European Negotiations Remain Unmoved 

Iranians walk next to Iran's national flags in Tehran, Iran, 20 September 2025. (EPA)
Iranians walk next to Iran's national flags in Tehran, Iran, 20 September 2025. (EPA)
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Iran’s Supreme Leader Rejects Direct Nuclear Talks with US as European Negotiations Remain Unmoved 

Iranians walk next to Iran's national flags in Tehran, Iran, 20 September 2025. (EPA)
Iranians walk next to Iran's national flags in Tehran, Iran, 20 September 2025. (EPA)

Iran's supreme leader on Tuesday rejected direct negotiations with the United States over his country's nuclear program, likely slamming the door shut on a last-ditch effort to halt the reimposition of United Nations sanctions on Tehran. 

Ali Khamenei's remarks, aired on Iranian state television, likely constrain any possible outreach to the US by Iranian President Masoud Pezeshkian, who is in New York for the UN General Assembly. Separately, Iranian Foreign Minister Abbas Araghchi held meetings there with diplomats from France, Germany and Britain over the reimposition of the sanctions, set to take effect Sunday. 

Talks with the US represent "a sheer dead end," Khamenei said. 

"The US has announced the results of the talks in advance," he added. "The result is the closure of nuclear activities and enrichment. This is not a negotiation. It is a diktat, an imposition." 

The German Foreign Office, in comments posted on X after the meeting with Araghchi, said that France, Germany, Britain and the EU urged Iran to take steps within days, "if not hours," to address concerns over its nuclear program. It should resume direct talks with the US and provide the International Atomic Energy Agency with access to all its nuclear sites, "in line with its obligations," the statement said. 

The three European countries, known as the E3, triggered the so-called "snapback" mechanism to reinstate sanctions — barring a last-minute accord — over Iran's failure to comply with conditions of a 2015 nuclear deal aimed at preventing Tehran from developing nuclear weapons. 

The meeting Tuesday did not appear to move closer to a resolution before Saturday’s deadline. But a French diplomat said that the European leaders plan to make "full use" of the remaining time. The diplomat spoke on condition of anonymity because they were not authorized to publicly discuss the private meeting. 

The German Foreign Office said "diplomatic engagement" would continue even if sanctions are reimposed Sunday. 

Earlier, Germany’s Foreign Minister Johann Wadephul had described the chance of reaching an agreement with Iran by the weekend "extremely slim," the German news agency dpa had reported, even before Khamenei’s comments. 

In his speech late Tuesday, French President Emmanuel Macron said the Middle East region can only be at peace if Iran’s nuclear program "is once again fully under control." 

"The next steps to come will be decisive," he said, adding that he’s willing to meet with Iran’s president this week to secure a deal. 

Iran has stopped inspectors, refused US talks  

Amid a flurry of diplomatic engagements, Araghchi on Monday also met with Rafael Grossi, the International Atomic Energy Agency (IAEA) director-general, in New York. 

Earlier this month, the UN nuclear watchdog and Iran signed an agreement mediated by Egypt to pave the way for resuming cooperation, including on ways of relaunching inspections of Iran’s nuclear facilities. However, that agreement has yet to fully take hold. 

In July, Pezeshkian signed a law adopted by his country’s parliament suspending all cooperation with the UN nuclear watchdog. That followed Israel’s 12-day war with Iran in June, during which Israel and the US bombed Iranian nuclear sites. 

France, Germany and the UK began the process of reimposing sanctions on Iran at the end of August. 

The process — termed a "snapback" by the diplomats who negotiated it into Iran’s 2015 nuclear deal with world powers — was designed to be veto-proof at the UN. It started a 30-day clock ticking for the resumption of sanctions unless the West and Iran reach a diplomatic agreement. 

European nations have said they would be willing to extend the deadline if Iran resumes direct negotiations with the US over its nuclear program, allows UN nuclear inspectors access to its nuclear sites, and accounts for the more than 400 kilograms (880 pounds) of highly enriched uranium the UN watchdog says it has. Iran is the only nation in the world that enriches uranium up to 60%, a short, technical step from weapons-grade levels, that does not have a weapons program. 

If no diplomatic deal is found this week, the sanctions will automatically "snapback" on Sunday. That would again freeze Iranian assets abroad, halt arms deals with Tehran and penalize any development of Iran’s ballistic missile program, among other measures, further squeezing the country’s reeling economy. 

Khamenei made a point in his roughly half-hour speech to say his comments focused only on America, not on Europe. 

Iran maintains its atomic program is peaceful Iran has long insisted its program is peaceful, though Western nations and the IAEA assess that Tehran had an active nuclear weapons program until 2003. Khamenei again pledged that Iran does not seek atomic bombs. 

"We do not have a nuclear bomb and we will not have one, and we do not plan to use nuclear weapon," he said. 

US President Donald Trump, who unilaterally withdrew America from the Iran nuclear deal in 2018, made a point to reference Tehran in his speech before the UN on Tuesday. He recounted writing a letter to Khamenei seeking talks. US and Iranian negotiators met five times before the 12-day war in June. 

"There is no more serious danger to our planet today than the most powerful and destructive weapons ever devised by man, of which the United States, as you know, has many," Trump said. "I’ve made containing these threats a top priority, starting with (the) nation of Iran." 

However, Khamenei stressed that Israeli and American attacks would not destroy the nuclear knowledge gained by Iran over the decades over the crisis surrounding the program. 

"Science will not be demolished by threats and bombing," he vowed. 



Russia Says It Hopes for New Round of Ukraine Talks with US as Soon as Conditions Allow

FILE PHOTO: Kremlin spokesman Dmitry Peskov looks on as Russia's President Vladimir Putin (not pictured) and Togo's President of the Council of Ministers Faure Gnassingbe (not pictured) meet at the Kremlin in Moscow, Russia November 19, 2025. REUTERS/Ramil Sitdikov/Pool/File Photo
FILE PHOTO: Kremlin spokesman Dmitry Peskov looks on as Russia's President Vladimir Putin (not pictured) and Togo's President of the Council of Ministers Faure Gnassingbe (not pictured) meet at the Kremlin in Moscow, Russia November 19, 2025. REUTERS/Ramil Sitdikov/Pool/File Photo
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Russia Says It Hopes for New Round of Ukraine Talks with US as Soon as Conditions Allow

FILE PHOTO: Kremlin spokesman Dmitry Peskov looks on as Russia's President Vladimir Putin (not pictured) and Togo's President of the Council of Ministers Faure Gnassingbe (not pictured) meet at the Kremlin in Moscow, Russia November 19, 2025. REUTERS/Ramil Sitdikov/Pool/File Photo
FILE PHOTO: Kremlin spokesman Dmitry Peskov looks on as Russia's President Vladimir Putin (not pictured) and Togo's President of the Council of Ministers Faure Gnassingbe (not pictured) meet at the Kremlin in Moscow, Russia November 19, 2025. REUTERS/Ramil Sitdikov/Pool/File Photo

Russia is in contact with the United States about a new round of talks on a Ukraine peace settlement as soon as conditions allow, the Kremlin said on Thursday.

"We remain open, we are in contact with the Americans, and we are counting on holding the next round of talks as soon ‌as circumstances permit," ‌Kremlin spokesman Dmitry Peskov said.

Peskov rejected ‌the ⁠thesis of a ⁠New York Times opinion piece that said the Iran war had caused President Vladimir Putin to lose interest in negotiating an end to the Ukraine conflict, Reuters reported.

"This is an absolutely false invention that does not correspond to reality. During the rounds of trilateral talks that ⁠have taken place, some progress was made ‌toward a settlement," Peskov told ‌reporters.

Peskov said Russia had not lost interest in peace ‌talks but added that key issues - including territory - had ‌yet to be settled.

The NYT opinion piece, by Russian journalist Mikhail Zygar, said Russia's economy had been faltering earlier this year, prompting Putin at that point to take negotiations on ‌a Ukraine settlement more seriously.

However, Zygar said the Iran war had reversed those dynamics by ⁠boosting ⁠oil prices, easing the economic pressure on Moscow and reducing the US focus on Ukraine, weakening any incentive for the Kremlin to seek a settlement.

Earlier this week, Kremlin aide Yuri Ushakov said the US had briefed Russia about Washington's latest round of talks with a Ukrainian delegation in Florida, which took place last Saturday.

The last three-way peace talks between Russia, Ukraine and the US took place last month, before the Trump administration and Israel began airstrikes against Iran on February 28.


Pentagon Reportedly Weighs Diverting Ukraine Military Aid to the Middle East

FILE - The Pentagon and the surrounding area is seen in this aerial view in Washington, Jan. 26, 2020. (AP Photo/Pablo Martinez Monsivais, File)
FILE - The Pentagon and the surrounding area is seen in this aerial view in Washington, Jan. 26, 2020. (AP Photo/Pablo Martinez Monsivais, File)
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Pentagon Reportedly Weighs Diverting Ukraine Military Aid to the Middle East

FILE - The Pentagon and the surrounding area is seen in this aerial view in Washington, Jan. 26, 2020. (AP Photo/Pablo Martinez Monsivais, File)
FILE - The Pentagon and the surrounding area is seen in this aerial view in Washington, Jan. 26, 2020. (AP Photo/Pablo Martinez Monsivais, File)

The Pentagon is weighing whether to redirect weapons originally meant for Ukraine to the Middle East, as the war in Iran strains supplies of some of the US military's most critical munitions, the Washington Post reported Thursday, citing three people familiar with the matter.

The weapons that could be redirected include air defense interceptor missiles purchased through a NATO initiative launched last year, under which ⁠partner countries buy ⁠US arms for Kyiv, the report said.

The consideration comes as US operations in the region intensify. Admiral Brad Cooper, the Central Command chief leading US forces in the Middle East, on Wednesday said the US had hit ⁠over 10,000 targets inside Iran and was on track to limit Iran's ability to project power outside its borders.

A Pentagon spokesperson told the newspaper that the Defense Department would "ensure that US forces and those of our allies and partners have what they need to fight and win."

In response to a query about the report, a NATO official said members of ⁠the ⁠alliance and its partners continue to contribute to its Prioritized Ukraine Requirements List (PURL) program that funds the supply of US arms for Kyiv.

"Equipment is continuously flowing into Ukraine," the official added. "The amount pledged to PURL so far is of several billion US dollars and we expect more contributions to follow."

The Pentagon and the US State Department did not immediately respond to Reuters' requests for comment.


Israel Defense Minister Says Iran Guards Navy Commander Killed in Strike

(FILES) This handout photo provided by Iran's Revolutionary Guard Corps (IRGC) official website Sepah News on February 1, 2025, shows navy commander Admiral Alireza Tangsiri. (Photo by SEPAH NEWS / AFP)
(FILES) This handout photo provided by Iran's Revolutionary Guard Corps (IRGC) official website Sepah News on February 1, 2025, shows navy commander Admiral Alireza Tangsiri. (Photo by SEPAH NEWS / AFP)
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Israel Defense Minister Says Iran Guards Navy Commander Killed in Strike

(FILES) This handout photo provided by Iran's Revolutionary Guard Corps (IRGC) official website Sepah News on February 1, 2025, shows navy commander Admiral Alireza Tangsiri. (Photo by SEPAH NEWS / AFP)
(FILES) This handout photo provided by Iran's Revolutionary Guard Corps (IRGC) official website Sepah News on February 1, 2025, shows navy commander Admiral Alireza Tangsiri. (Photo by SEPAH NEWS / AFP)

Defense Minister Israel Katz announced on Thursday that an Israeli airstrike had killed Alireza Tangsiri, commander of the Iranian Revolutionary Guards' navy.

"Last night, in a precise and lethal operation, the IDF eliminated the commander of the Revolutionary Guards' navy, Tangsiri, along with senior officers of the naval command," Katz said in a video statement.

"The man who was directly responsible for the terrorist operation of mining and blocking the Strait of Hormuz to shipping was blown up and eliminated."

Since the start of the joint US-Israeli attacks on Iran on February 28, Israel has announced the killing of several top Iranian officials, including supreme leader Ali Khamenei and the security chief, Ali Larijani.

In recent days, Israeli forces have carried out several strikes targeting the naval assets of Iran.

Last week, Israeli airstrikes hit several Iranian naval ships in the Caspian Sea, including ones equipped with missile systems, support vessels and patrol craft.