Israeli airstrikes on three houses in the southern Gaza city of Rafah killed at least 22 Palestinians and wounded many others, medics said on Monday.
Israel has regularly carried out airstrikes on Rafah since the start of the war and has threatened to send in ground troops, saying Rafah is the last major Hamas stronghold in the coastal enclave. Over a million Palestinians have sought refuge in the city on the Egyptian border.
An assault on Rafah has been anticipated for weeks but foreign governments and the United Nations have expressed concern that such action could result in a humanitarian disaster given the number of displaced people crammed into the area.
The overnight strikes hit three family homes. The first killed 11 people, including four siblings aged 9 to 27, according to records at the Abu Yousef al-Najjar Hospital, where the bodies were taken. The second strike killed eight people, including a 33-year-old father and his 5-day-old boy, according to hospital records. The third strike killed three siblings, aged 23, 19 and 12.