At least seven people have died from a cholera outbreak over the past three weeks in the southeastern Blu Nile province in Sudan, said the Health Ministry on Monday.
Dozens have also been infected, it added.
No cases have been reported in other provinces.
Authorities said 16 of Sudan's 18 provinces have been affected by heavy rains and flash floods in late August, the worst since 2013.
The World Health Organization announced new malaria cases have also been reported in several Sudanese provinces.
Naeema Al Gasseer, the WHO representative in Sudan, had recently warned of a risk of cholera and other intestinal diseases spreading if there's "no immediate response interventions."