Portals to History and Conflict: The Gates of Jerusalem's Old City

People are seen near Damascus Gate in Jerusalem's Old City October 7, 2019. (Reuters)
People are seen near Damascus Gate in Jerusalem's Old City October 7, 2019. (Reuters)
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Portals to History and Conflict: The Gates of Jerusalem's Old City

People are seen near Damascus Gate in Jerusalem's Old City October 7, 2019. (Reuters)
People are seen near Damascus Gate in Jerusalem's Old City October 7, 2019. (Reuters)

Muslims, Christians and Jews pass daily through the gates of Jerusalem’s Old City, on their way to and from prayers or simply to go about their everyday business in one of the most politically sensitive spots on earth.

There are eight gates - seven are open and one is sealed - along the Old City walls that were built in the 16th century by Turkish sultan Suleiman the Magnificent.

It’s always busy at Damascus Gate, the main entrance to the Muslim quarter, and at Jaffa Gate, facing west toward the Mediterranean, where local residents and tourists mix in markets lining stone alleyways, said Reuters.

Lion’s Gate - two pairs of heraldic lions are carved on the archway - is also known as St. Stephen’s Gate. It faces east, toward ancient Jericho. It is often crowded with Muslim worshippers after prayers at al-Aqsa mosque, Islam’s third holiest shrine.

Many Jewish worshippers take another route to Judaism’s nearby Western Wall. They pass through the Dung Gate, the closest entrance to the holy place, and Jewish families on their way to celebrate a 13-year-old son’s Bar Mitzvah can be spotted making their way to the wall.

Security is always tight in a volatile area at the heart of the Israeli-Palestinian conflict. Israeli police patrol and closed-circuit TV cameras monitor the passageways of the Old City.

Palestinians want East Jerusalem, where the Old City is located, as the capital of a state they seek to establish in the occupied West Bank and Gaza Strip.

Israel views all of Jerusalem, including the walled Old City that it captured in the 1967 Middle East war, as its “eternal and indivisible” capital.



Axsome's Alzheimer's-related Drug Shows Mixed Results in Late-stage Studies

The human brain. Illustration: AFP
The human brain. Illustration: AFP
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Axsome's Alzheimer's-related Drug Shows Mixed Results in Late-stage Studies

The human brain. Illustration: AFP
The human brain. Illustration: AFP

Axsome Therapeutics said on Monday its experimental drug to treat agitation related to Alzheimer's disease succeeded in one of the two late-stage studies and failed to meet the main goal of the second trial.

Shares of the drug developer, which was testing the treatment, AXS-05, dropped 12% in premarket trading, Reuters reported.

The agitation is a symptom that causes emotional distress as well as verbal and physical aggressiveness.

The treatment significantly delayed the time to relapse in agitation as measured on a disease severity scale in one study, but did not demonstrate statistical significance in delaying agitation in another late-stage trial.

AXS-05 was safe and well tolerated in both the studies, the company said.