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Scientists 3D Print Human Heart Muscles

A human embryonic stem cell line derived at Stanford University. (REUTERS/Julie Baker/Stanford University School of Medicine/California Institute for Regenerative Medicine/Handout)
A human embryonic stem cell line derived at Stanford University. (REUTERS/Julie Baker/Stanford University School of Medicine/California Institute for Regenerative Medicine/Handout)
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Scientists 3D Print Human Heart Muscles

A human embryonic stem cell line derived at Stanford University. (REUTERS/Julie Baker/Stanford University School of Medicine/California Institute for Regenerative Medicine/Handout)
A human embryonic stem cell line derived at Stanford University. (REUTERS/Julie Baker/Stanford University School of Medicine/California Institute for Regenerative Medicine/Handout)

Heart diseases are the leading cause of death in the United States killing more than 600,000 people a year. A team of researchers at the University of Minnesota has 3D printed a functioning human heart pump in the lab, which could help save the lives of thousands of patients.

According to the Science Daily website, the researchers used a type of stem cells with the potential to develop into any type of cell in the body, in addition to a mix of proteins, and the printer's ink.

The heart muscle model is about 1.5 centimeters long and was specifically designed to fit into the abdominal cavity of a mouse for further study, the German News Agency reported.

The team said the new muscle can be used to study the functions of the heart, and the problems that might affect it.

Brenda Ogle from the Department of Biomedical Engineering in the University of Minnesota College, said this is a critical advance in heart research because this new study shows how we were able to 3D print heart muscle cells in a way that the cells could organize and work together.

"We now have a model to track and trace what is happening at the cell and molecular level. We can introduce disease and damage into the model and then study the effects of medicines and other therapeutics," she explained.

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Farmed Production of Some Fish - and Seaweed - is Soaring

Farmed salmon -- like the ones grown in pens here in the Australian island state of Tasmania -- are easier to grow than some other fish species. Gregory PLESSE / AFP/File
Farmed salmon -- like the ones grown in pens here in the Australian island state of Tasmania -- are easier to grow than some other fish species. Gregory PLESSE / AFP/File
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Farmed Production of Some Fish - and Seaweed - is Soaring

Farmed salmon -- like the ones grown in pens here in the Australian island state of Tasmania -- are easier to grow than some other fish species. Gregory PLESSE / AFP/File
Farmed salmon -- like the ones grown in pens here in the Australian island state of Tasmania -- are easier to grow than some other fish species. Gregory PLESSE / AFP/File

The amount of farmed seafood we consume -- as opposed to that taken wild from our waters -- is soaring every year, making aquaculture an ever-more important source for many diets, and a response to overfishing.

According to the UN's Food and Agriculture Organization, nearly 99 million tons of aquatic animals (fish, molluscs like oysters and mussels and crustaceans like prawns) were farmed around the world in 2023, five times more than three decades ago.

Since 2022, the farming of aquatic animals has been steadily overtaking fishing around the world -- but with large disparities from species to species.

Fast-growing species

The two biggest sellers on the market in 2023, carp and tilapia, mainly came from freshwater farming, while other widely-consumed fish, like herring, came just from deep sea fishing

Thierry Laugier, a researcher at Ifremer, France's national institute for ocean science and technology, told AFP that fish farmers choose species that grow quickly and with simple requirements, to be able to control the life cycle.

Sales of the most widely farmed fish in Europe, Atlantic salmon, came to 1.9 million tons in 2023, 99 percent of which were farmed.

"We know how to control the ageing or how to launch a reproduction cycle, through injecting hormones," Laugier said.

Asia main producer
Asia is by far the biggest producer of farmed fish, accounting for 92 percent of the 136 million tons -- of both animal and plant species -- produced under manmade conditions in 2023.

"For carp, it comes down to tradition, it has been farmed for thousands of years on the Asian continent," the Ifremer researcher said.

At the other end of the spectrum, sardines and herring are just fished in the oceans, mainly for profitability reasons as some fish grow very slowly.

"It takes around two years to get an adult-sized sardine," Laugier said.

He said farming of some fish has not yet been started as, "for a long time, we thought the ocean was an inexhaustible resource".

Seaweed

Little known in the West, seaweed nevertheless accounts for almost a third of world aquaculture production.

Almost exclusively from Asia, seaweed production increased by nearly 200 percent in two decades, to 38 million tons. It is mainly used in industry, in jellies, pharmaceuticals and cosmetics, the expert said.

He said seaweed also has the major advantage of absorbing not just CO2 in the oceans, but also nitrogen and certain pollutants.

"And from an ecological point of view it is better to farm macroalgae than salmon," Laugier said.